SE7510196L - Sett att framstella nya 2,3-dihydro-1-bensotiepin-4-karboxylsyraamider - Google Patents

Sett att framstella nya 2,3-dihydro-1-bensotiepin-4-karboxylsyraamider

Info

Publication number
SE7510196L
SE7510196L SE7510196A SE7510196A SE7510196L SE 7510196 L SE7510196 L SE 7510196L SE 7510196 A SE7510196 A SE 7510196A SE 7510196 A SE7510196 A SE 7510196A SE 7510196 L SE7510196 L SE 7510196L
Authority
SE
Sweden
Prior art keywords
dihydro
benzotiepine
carboxylic acid
acid amides
making new
Prior art date
Application number
SE7510196A
Other languages
English (en)
Other versions
SE420725B (sv
Inventor
M H Rosen
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE7510196L publication Critical patent/SE7510196L/sv
Publication of SE420725B publication Critical patent/SE420725B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7510196A 1974-09-26 1975-09-12 Sett att framstella 2,3-dihydro-1-benstiepin-4-karboxylsyraamider SE420725B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US50952474A 1974-09-26 1974-09-26
US58514775A 1975-06-09 1975-06-09
US74320876A 1976-11-18 1976-11-18
US05/854,176 US4185109A (en) 1974-09-26 1977-11-23 1-Benzothiepin-4-carboxamides

Publications (2)

Publication Number Publication Date
SE7510196L true SE7510196L (sv) 1976-03-29
SE420725B SE420725B (sv) 1981-10-26

Family

ID=27504481

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7510196A SE420725B (sv) 1974-09-26 1975-09-12 Sett att framstella 2,3-dihydro-1-benstiepin-4-karboxylsyraamider

Country Status (10)

Country Link
US (1) US4185109A (sv)
AT (1) AT346338B (sv)
AU (1) AU496764B2 (sv)
BE (1) BE833787A (sv)
CA (1) CA1066279A (sv)
CH (3) CH617433A5 (sv)
DE (1) DE2542329C2 (sv)
FR (1) FR2285872A1 (sv)
NL (1) NL7511316A (sv)
SE (1) SE420725B (sv)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242266A (en) * 1974-09-26 1980-12-30 Ciba-Geigy Corporation 1-Benzothiepin-4-carboxylic acid derivatives
US4277484A (en) * 1978-09-20 1981-07-07 Ciba-Geigy Corporation 1-Benzothiepin-4-carboxamides
US4582850A (en) * 1985-02-28 1986-04-15 Ciba-Geigy Corporation Topical and systemic treatment of psoriasis using 7-chloro-N-(3,4-dichlorophenyl)-2,3-dihydro-5-hydroxy-1-benzothiepin-4-carboxamide 1,1-dioxide and pharmaceutically acceptable salts thereof
US4803197A (en) * 1987-01-12 1989-02-07 Ciba-Geigy Corporation 2,1-benzothiazepine-2,2-dioxide-5-carboxylic acid derivatives
US6268392B1 (en) 1994-09-13 2001-07-31 G. D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
US6642268B2 (en) 1994-09-13 2003-11-04 G.D. Searle & Co. Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
US6262277B1 (en) 1994-09-13 2001-07-17 G.D. Searle And Company Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US6221897B1 (en) * 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
EP1140185B1 (en) 1998-12-23 2003-06-04 G.D. Searle LLC. Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
US6462091B1 (en) 1998-12-23 2002-10-08 G.D. Searle & Co. Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications
AU779264B2 (en) * 1998-12-23 2005-01-13 G.D. Searle Llc Combinations for cardiovascular indications
HUP0104793A2 (en) 1998-12-23 2002-06-29 Searle Llc Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
CA2356157C (en) 1998-12-23 2008-04-01 G.D. Searle Llc Combinations of cholesteryl ester transfer protein inhibitors and fibric acid derivatives for cardiovascular indications
CZ20012345A3 (cs) * 1998-12-23 2001-12-12 G. D. Searle Llc Corporate Patent Department Kombinace inhibitorů transportu kyčelní ľlučové kyseliny a činidel pro sekvenci ľlučové kyseliny pro kardiovaskulární indikace
DK1140188T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af ileale galdesyretransporthæmmere og cholesterylestere tranferproteinhæmmere til cardiovaskulære indikationer
DK1140184T3 (da) 1998-12-23 2003-09-29 Searle Llc Kombinationer af cholesterylestertransferproteinhæmmere og nikotinsyrederivater til hjertekar indikationer
AU2001247331A1 (en) * 2000-03-10 2001-09-24 Pharmacia Corporation Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
US6794544B2 (en) 2000-03-10 2004-09-21 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20040077625A1 (en) * 2001-07-25 2004-04-22 Tremont Samuel J. Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
CA2464685A1 (en) * 2001-11-02 2003-05-15 G.D. Searle Llc Novel mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (asbt) and taurocholate uptake
AU2003207431A1 (en) 2002-01-17 2003-09-02 Pharmacia Corporation Novel alkyl/aryl hydroxy or keto thiepines.
PL2771003T3 (pl) 2011-10-28 2017-10-31 Lumena Pharmaceuticals Llc Inhibitory ponownego wykorzystania kwasów żółciowych do leczenia pediatrycznych cholestatycznych chorób wątroby

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3287368A (en) * 1965-06-08 1966-11-22 Mcneilab Inc Dihydrobenzothiepin-5(2h)-one oximes
US3287370A (en) * 1965-06-08 1966-11-22 Mcneilab Inc Tetrahydrobenzothiepins
US3389144A (en) * 1965-06-08 1968-06-18 Mcneilab Inc 5-pyridyl-2, 3, 4, 5-tetrahydrobenzothiepin-5-ols
US3444176A (en) * 1967-04-28 1969-05-13 Mcneilab Inc Certain 4-diloweralkylamino-lower alkyl - 5 - pyridyl (or phenyl)-2,3-dihydro - 1 - benzothiepins and derivatives thereof
US3505355A (en) * 1968-08-12 1970-04-07 Mcneilab Inc Certain dihydrobenzo-thiepin-5(2h)-ones
DE2264938A1 (de) * 1971-07-15 1975-06-12 Warner Lambert Co 3-arylaminocarbonyl-4-hydroxy-benzo eckige klammer auf b eckige klammer zu thiacyclohex(3)en-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US3769292A (en) * 1972-04-28 1973-10-30 Warner Lambert Co N-(pyridyl)2h 1-benzothiopyran-3-carboxamide-4-hydroxy 1,1-dioxides
US3828055A (en) * 1972-04-28 1974-08-06 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2h-1-benzothiopyran-3-carboxylic acid 1,1-dioxide
US3826791A (en) * 1972-04-28 1974-07-30 Warner Lambert Co Heterocyclic amides of 4-hydroxy-2h-1-benzothiopyran-3-carboxylic acid 1,1-dioxide and process for their production
US3962261A (en) * 1974-02-04 1976-06-08 Warner-Lambert Company 2,3,4,5-tetra hydro-5-oxo-1-benzothiepi n-4-carboxamide 1,1-dioxides

Also Published As

Publication number Publication date
AU496764B2 (en) 1978-10-26
CH617433A5 (sv) 1980-05-30
FR2285872B1 (sv) 1978-11-10
ATA734175A (de) 1978-03-15
NL7511316A (nl) 1976-03-30
US4185109A (en) 1980-01-22
BE833787A (fr) 1976-03-25
DE2542329A1 (de) 1976-04-15
CH623581A5 (sv) 1981-06-15
SE420725B (sv) 1981-10-26
DE2542329C2 (de) 1984-05-24
AU8514875A (en) 1977-03-31
FR2285872A1 (fr) 1976-04-23
AT346338B (de) 1978-11-10
CA1066279A (en) 1979-11-13
CH623580A5 (sv) 1981-06-15

Similar Documents

Publication Publication Date Title
SE7510196L (sv) Sett att framstella nya 2,3-dihydro-1-bensotiepin-4-karboxylsyraamider
AR205196A1 (es) Procedimiento de preparacion de derivados de acidos n n'-bis(triiodocarbamoil - amino - benzoil)-diamino-alcanoicos
SE416298B (sv) Forfarande for framstellning av nya bensimidazolinon derivat
IT1066280B (it) Procedimento per la produzione di tetraidro 1.4 ossazine n sostituite
SE7705143L (sv) Nya omega-aminokarboxylsyraamider jemte sett for deras framstellning
BE835268A (fr) Derives de l'acide furannehydroxyamique
GB1471847A (en) Dibenzofuran derivatives
IT1041201B (it) Procedimento per la produzione di 2 metil tetraidro pirimidine i sostituite
DK137533C (da) Analogifremgangsmaade til fremstilling af 2-carbalkoxyaminobenzimidazolyl-5(6)-sulfonsyrephenylestere
IT1061249B (it) Procedimento per la fabbricazione di 3 5 diterz butil 4 idrossibenzal deide mediante formilazione di 2 6 diterz butilfenolo
SE7506674L (sv) Forfarande for framstellning av arylalkansyror innehallande dihydrofuran- eller dihydropyranringar
IT1026236B (it) Procedimento per la produzione di 3 amminopirazoli
IT1044498B (it) Procedimento per la produzione di ditionito di sodio
SU624570A3 (ru) Способ получени аминов или их солей
SE7512746L (sv) Sett att framstella nya 7,7-difenyl-hexahydro-1,4-oxazepiner
DK209275A (da) Fremgangsmade til fremstilling af 2,3-polymethylen-5-sulfamoylbenzoesyreforbindelser
SE7505272L (sv) Nya, kvevehaltiga, polycykliska foreningar jemte sett for deras framstellning.
FR2313021A1 (fr) Derives de l'acide prostenoique
DK519975A (da) Fremgangsmade til fremstilling af 6', 2-(2'-arylkromonyl)-propionsyrer
BE830469A (fr) Procede de preparation d'acetoxybutanal
SU660588A3 (ru) Способ получени бензиламиноалкановых кислот или их солей
SE7504509L (sv) Nya aminoacylforeningar.
AR210330A1 (es) Peocedimiento para la produccion de compuestos de 1 o 7-(-1)-hidroxialquilaxantina
SU521251A1 (ru) Способ получени дибензоилнафталиндикарбоновой кислоты
SU499852A2 (ru) Установка дл формировани скирд

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7510196-4

Effective date: 19891002

Format of ref document f/p: F