SE7500793L - - Google Patents

Info

Publication number
SE7500793L
SE7500793L SE7500793A SE7500793A SE7500793L SE 7500793 L SE7500793 L SE 7500793L SE 7500793 A SE7500793 A SE 7500793A SE 7500793 A SE7500793 A SE 7500793A SE 7500793 L SE7500793 L SE 7500793L
Authority
SE
Sweden
Prior art keywords
formula
compound
nhr1
radical
reacting
Prior art date
Application number
SE7500793A
Other versions
SE421617B (en
Inventor
G Agato
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SE7500793L publication Critical patent/SE7500793L/xx
Publication of SE421617B publication Critical patent/SE421617B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/121Heterocyclic compounds containing oxygen or sulfur as hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/116Heterocyclic compounds
    • A23K20/137Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C07D333/80Seven-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Feed For Specific Animals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The novel compounds correspond to the formula: <IMAGE> in which X, Y, Z, R1, R2, R3 and U have the meanings given in Claim 1. They are prepared by a) reacting one mol equivalent of a compound of the formula I or II, in which the -NR1-CX-NHR1 radical is replaced, or its acid addition salts with 1 to 1.5 mol equivalents of R2NCX or b) reacting one mol equivalent of an acid addition salt of a compound of the formula I or II, in which R2 and R3 denotes hydrogen and the -NR1-CX-NHR2 radical is replaced by -NHR1, with 1 to 1.5 mol equivalents of a compound of the formula MeNCX, in which Me denotes sodium or potassium, and isolating the product. The reaction (a) is carried out in water or an inert organic solvent at 0 to 100 DEG C. The reaction (b) is carried out in aqueous medium at pH = 5 to 7 and 10 to 80 DEG C. The novel compounds of the formulae I and II are administered orally to warm-blooded animals to improve the extent of the feed effect and to increase the growth rate. A supplementary feed for increasing the growth rate of poultry, fur-bearing animals and agricultural productive animals contains 70 to 99% by weight of an edible carrier and, as the remainder, a novel compound of the formula I or II.
SE7500793A 1974-01-25 1975-01-24 CYCLOAL ALKANO (B) TIENYLCARBAMIDE ASSOCIATIONS WITH ANIMAL GROWTH PROMOTIONAL EFFECTS SE421617B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43682774A 1974-01-25 1974-01-25
US43682674A 1974-01-25 1974-01-25

Publications (2)

Publication Number Publication Date
SE7500793L true SE7500793L (en) 1975-07-28
SE421617B SE421617B (en) 1982-01-18

Family

ID=27031116

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7500793A SE421617B (en) 1974-01-25 1975-01-24 CYCLOAL ALKANO (B) TIENYLCARBAMIDE ASSOCIATIONS WITH ANIMAL GROWTH PROMOTIONAL EFFECTS

Country Status (21)

Country Link
JP (1) JPS51125069A (en)
AT (1) AT353590B (en)
CA (1) CA1060899A (en)
CH (4) CH619703A5 (en)
CS (1) CS195276B2 (en)
DD (4) DD125213A5 (en)
DE (1) DE2501788C2 (en)
DK (1) DK22775A (en)
ES (1) ES434095A1 (en)
FR (1) FR2333801A1 (en)
GB (1) GB1499582A (en)
IE (1) IE42039B1 (en)
IL (1) IL46375A (en)
IN (1) IN141050B (en)
IT (1) IT1035548B (en)
LU (1) LU71711A1 (en)
NL (1) NL7500845A (en)
PH (1) PH14544A (en)
SE (1) SE421617B (en)
TR (1) TR18381A (en)
YU (1) YU36721B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994924A (en) * 1975-11-04 1976-11-30 American Cyanamid Company 4,5,6,7-Tetra hydro-7-oxobenzo(B)thien-4-yl isocyanate and isothiocyanate
FR2430231A1 (en) * 1978-07-04 1980-02-01 American Cyanamid Co 4,5,6,7-Tetra:hydro-benzo(b)thienyl-4 urea and 7-oxo deriv. compsn. - used for increasing growth of wool and ratio of sec. to prim. follicles in sheep, goats, llamas, rabbits and chinchilla
JPS6169772A (en) * 1984-12-04 1986-04-10 アメリカン サイアナミッド カンパニ− Tetrahydrobenzo(b)thiophene derivative, manufacture and animal growth acceleration
EP1801098A1 (en) 2005-12-16 2007-06-27 Merck Sante 2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors

Also Published As

Publication number Publication date
DD125212A5 (en) 1977-04-06
DK22775A (en) 1975-09-15
YU36721B (en) 1984-08-31
AT353590B (en) 1979-11-26
IT1035548B (en) 1979-10-20
YU17275A (en) 1982-06-18
IL46375A (en) 1982-04-30
CS195276B2 (en) 1980-01-31
TR18381A (en) 1977-05-01
ATA42675A (en) 1979-04-15
IN141050B (en) 1977-01-15
CH619949A5 (en) 1980-10-31
AU7691574A (en) 1976-07-01
SE421617B (en) 1982-01-18
IL46375A0 (en) 1975-04-25
DD125213A5 (en) 1977-04-06
DE2501788C2 (en) 1984-11-08
GB1499582A (en) 1978-02-01
PH14544A (en) 1981-09-24
ES434095A1 (en) 1977-05-16
CH619703A5 (en) 1980-10-15
JPS6133830B2 (en) 1986-08-04
CH619704A5 (en) 1980-10-15
CA1060899A (en) 1979-08-21
FR2333801B1 (en) 1982-07-09
FR2333801A1 (en) 1977-07-01
CH619705A5 (en) 1980-10-15
JPS51125069A (en) 1976-11-01
DD125211A5 (en) 1977-04-06
NL7500845A (en) 1975-07-29
IE42039B1 (en) 1980-05-21
LU71711A1 (en) 1975-06-24
DD119790A5 (en) 1976-05-12
IE42039L (en) 1975-07-25
DE2501788A1 (en) 1975-07-31

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