SE7412215L - - Google Patents
Info
- Publication number
- SE7412215L SE7412215L SE7412215A SE7412215A SE7412215L SE 7412215 L SE7412215 L SE 7412215L SE 7412215 A SE7412215 A SE 7412215A SE 7412215 A SE7412215 A SE 7412215A SE 7412215 L SE7412215 L SE 7412215L
- Authority
- SE
- Sweden
- Prior art keywords
- deoxy
- product
- antibiotic
- tetracyclins
- doxycyclin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The novel antibiotic product of the general formula <IMAGE> has a high solubility in water at neutral pH and can be administered by the oral, intramuscular or intravenous route. The antibiotic activity of the doxycyclin is preserved unchanged. The product shows higher tolerance, stability and blood levels superior to those of 6-deoxy-tetracyclins and derivatives thereof, lower toxicity, yet retains the antibiotic properties of the 6-deoxy-tetracyclins. The product is prepared by contacting a 6-deoxy-tetracyclin with an equimolar quantity of methionine in the presence of formaldehyde in a polar solvent at a temperature of 10-80 DEG C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2948673 | 1973-09-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7412215L true SE7412215L (en) | 1975-03-29 |
| SE398875B SE398875B (en) | 1978-01-23 |
Family
ID=11227072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7412215A SE398875B (en) | 1973-09-28 | 1974-09-27 | PROCEDURE FOR THE PREPARATION OF AN ADDUCT COMPOUND OF 6-DEOXITETRACYCLINE AND METHIONINE |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS6044293B2 (en) |
| AT (1) | AT337359B (en) |
| BE (1) | BE820474A (en) |
| CA (1) | CA1031774A (en) |
| CH (1) | CH614190A5 (en) |
| DE (1) | DE2446586A1 (en) |
| DK (1) | DK153784C (en) |
| ES (1) | ES430512A1 (en) |
| FR (1) | FR2246275B1 (en) |
| GB (1) | GB1484345A (en) |
| IL (1) | IL45741A (en) |
| NL (1) | NL7412764A (en) |
| NO (1) | NO140345C (en) |
| SE (1) | SE398875B (en) |
| ZA (1) | ZA746147B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6442586U (en) * | 1987-09-07 | 1989-03-14 | ||
| CN102688492A (en) * | 2007-03-23 | 2012-09-26 | 分子研究中心公司 | Compositions and methods for anti-inflammatory treatments |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES262241A1 (en) * | 1959-11-23 | 1961-02-01 | Erba Carlo Spa | Procedure for preparing new derivatives of tetracycline antibiotics (Machine-translation by Google Translate, not legally binding) |
| BE615425A (en) * | 1961-03-24 | 1962-07-16 | Erba Carlo Spa | New salts of derivatives of tetracycline antibiotics |
-
1974
- 1974-09-24 DK DK501674A patent/DK153784C/en active
- 1974-09-25 CA CA210,080A patent/CA1031774A/en not_active Expired
- 1974-09-25 IL IL45741A patent/IL45741A/en unknown
- 1974-09-26 NO NO743489A patent/NO140345C/en unknown
- 1974-09-26 GB GB41918/74A patent/GB1484345A/en not_active Expired
- 1974-09-26 AT AT776274A patent/AT337359B/en not_active IP Right Cessation
- 1974-09-27 ZA ZA00746147A patent/ZA746147B/en unknown
- 1974-09-27 SE SE7412215A patent/SE398875B/en not_active IP Right Cessation
- 1974-09-27 CH CH1305774A patent/CH614190A5/en not_active IP Right Cessation
- 1974-09-27 BE BE149013A patent/BE820474A/en not_active IP Right Cessation
- 1974-09-27 NL NL7412764A patent/NL7412764A/en not_active Application Discontinuation
- 1974-09-28 JP JP49112212A patent/JPS6044293B2/en not_active Expired
- 1974-09-28 ES ES430512A patent/ES430512A1/en not_active Expired
- 1974-09-30 DE DE19742446586 patent/DE2446586A1/en not_active Withdrawn
- 1974-09-30 FR FR7432896A patent/FR2246275B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NO140345B (en) | 1979-05-07 |
| AU7381274A (en) | 1976-04-01 |
| IL45741A0 (en) | 1974-11-29 |
| NL7412764A (en) | 1975-04-02 |
| DE2446586A1 (en) | 1975-04-03 |
| IL45741A (en) | 1977-12-30 |
| FR2246275A1 (en) | 1975-05-02 |
| NO140345C (en) | 1979-08-15 |
| JPS6044293B2 (en) | 1985-10-02 |
| AT337359B (en) | 1977-06-27 |
| GB1484345A (en) | 1977-09-01 |
| JPS5062970A (en) | 1975-05-29 |
| NO743489L (en) | 1975-04-28 |
| DK153784C (en) | 1989-01-23 |
| DK501674A (en) | 1975-05-26 |
| SE398875B (en) | 1978-01-23 |
| DK153784B (en) | 1988-09-05 |
| CA1031774A (en) | 1978-05-23 |
| CH614190A5 (en) | 1979-11-15 |
| BE820474A (en) | 1975-01-16 |
| FR2246275B1 (en) | 1978-07-21 |
| ES430512A1 (en) | 1977-01-16 |
| ATA776274A (en) | 1976-10-15 |
| ZA746147B (en) | 1975-11-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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