SE7509984L - PROCEDURE FOR THE PREPARATION OF ACYL DERIVATIVE OF 7-AMINO-3-DESACETOXICEPHALOSPORANIC ACID - Google Patents

PROCEDURE FOR THE PREPARATION OF ACYL DERIVATIVE OF 7-AMINO-3-DESACETOXICEPHALOSPORANIC ACID

Info

Publication number
SE7509984L
SE7509984L SE7509984A SE7509984A SE7509984L SE 7509984 L SE7509984 L SE 7509984L SE 7509984 A SE7509984 A SE 7509984A SE 7509984 A SE7509984 A SE 7509984A SE 7509984 L SE7509984 L SE 7509984L
Authority
SE
Sweden
Prior art keywords
amino
preparation
desacetoxicephalosporanic
procedure
acid
Prior art date
Application number
SE7509984A
Other languages
Unknown language ( )
Swedish (sv)
Inventor
K Kunugita
E Igushi
H Aoki
H Imanaka
T Kamiya
K Tanaka
Y Shiokawa
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of SE7509984L publication Critical patent/SE7509984L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Novel 7-(3-alkanesulfonamidophenyl-0-glycinamido)-3-methyl-3-cephem-4-carboxylic acid and salts thereof of formula (I): (I) wherein R is an alkyl group of 1 to 6 carbon atoms are provided and their process of preparation in the presence of a culture broth derived from a microorganism selected from the genus Pseudomans. Xanthomonas and Acetobacter, effective to Nacylate the 7-amino-3-methyl-3-cephem-4-carboxylic acid or a salt thereof with 3-alkanesulfonamidophenylglycine the novel compounds are effective antimicrobial agents for oral application and are superior to the known cephalexin.
SE7509984A 1974-09-09 1975-09-08 PROCEDURE FOR THE PREPARATION OF ACYL DERIVATIVE OF 7-AMINO-3-DESACETOXICEPHALOSPORANIC ACID SE7509984L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49104243A JPS5132792A (en) 1974-09-09 1974-09-09 77 * 33 arukansuruhoniruaminofueniru dd gurishinamido * 33 mechiru 33 sefuemu 44 karubonsanrui no seizoho

Publications (1)

Publication Number Publication Date
SE7509984L true SE7509984L (en) 1976-03-10

Family

ID=14375498

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7509984A SE7509984L (en) 1974-09-09 1975-09-08 PROCEDURE FOR THE PREPARATION OF ACYL DERIVATIVE OF 7-AMINO-3-DESACETOXICEPHALOSPORANIC ACID

Country Status (7)

Country Link
JP (1) JPS5132792A (en)
AT (1) AT340049B (en)
CA (1) CA1055415A (en)
DK (1) DK401275A (en)
HU (1) HU169999B (en)
NL (1) NL7510606A (en)
SE (1) SE7509984L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6222328A (en) * 1985-07-19 1987-01-30 株式会社マキタ Selector switch

Also Published As

Publication number Publication date
ATA691675A (en) 1977-03-15
NL7510606A (en) 1976-03-11
DK401275A (en) 1976-03-10
CA1055415A (en) 1979-05-29
JPS5733036B2 (en) 1982-07-14
AT340049B (en) 1977-11-25
HU169999B (en) 1977-03-28
JPS5132792A (en) 1976-03-19

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