SE7408140L - - Google Patents
Info
- Publication number
- SE7408140L SE7408140L SE7408140A SE7408140A SE7408140L SE 7408140 L SE7408140 L SE 7408140L SE 7408140 A SE7408140 A SE 7408140A SE 7408140 A SE7408140 A SE 7408140A SE 7408140 L SE7408140 L SE 7408140L
- Authority
- SE
- Sweden
- Prior art keywords
- opium alkaloid
- derivative
- opium
- alkaloid
- carrier material
- Prior art date
Links
- 239000008896 Opium Substances 0.000 abstract 14
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 14
- 229960001027 opium Drugs 0.000 abstract 14
- 229930013930 alkaloid Natural products 0.000 abstract 12
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 239000012876 carrier material Substances 0.000 abstract 4
- 230000002163 immunogen Effects 0.000 abstract 4
- 210000004369 blood Anatomy 0.000 abstract 3
- 239000008280 blood Substances 0.000 abstract 3
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 3
- 108010074605 gamma-Globulins Proteins 0.000 abstract 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 3
- LMDZBCPBFSXMTL-UHFFFAOYSA-N 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide Chemical compound CCN=C=NCCCN(C)C LMDZBCPBFSXMTL-UHFFFAOYSA-N 0.000 abstract 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 229940098773 bovine serum albumin Drugs 0.000 abstract 2
- OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 abstract 2
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 210000002966 serum Anatomy 0.000 abstract 2
- KCYXYAIVKQSDFP-WMRVMTBBSA-N 2-[[(4r,4ar,7s,7ar,12bs)-7-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-9-yl]oxy]acetic acid Chemical compound O[C@H]([C@@H]1O2)C=C[C@H]3[C@]4([H])N(C)CC[C@]13C1=C2C(OCC(O)=O)=CC=C1C4 KCYXYAIVKQSDFP-WMRVMTBBSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- GVGLGOZIDCSQPN-PVHGPHFFSA-N Heroin Chemical compound O([C@H]1[C@H](C=C[C@H]23)OC(C)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4OC(C)=O GVGLGOZIDCSQPN-PVHGPHFFSA-N 0.000 abstract 1
- 108091006905 Human Serum Albumin Proteins 0.000 abstract 1
- 102000008100 Human Serum Albumin Human genes 0.000 abstract 1
- UIQMVEYFGZJHCZ-SSTWWWIQSA-N Nalorphine Chemical compound C([C@@H](N(CC1)CC=C)[C@@H]2C=C[C@@H]3O)C4=CC=C(O)C5=C4[C@@]21[C@H]3O5 UIQMVEYFGZJHCZ-SSTWWWIQSA-N 0.000 abstract 1
- 241000283973 Oryctolagus cuniculus Species 0.000 abstract 1
- 108010039918 Polylysine Proteins 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 abstract 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 abstract 1
- 235000011130 ammonium sulphate Nutrition 0.000 abstract 1
- 239000001166 ammonium sulphate Substances 0.000 abstract 1
- 239000012431 aqueous reaction media Substances 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229960004126 codeine Drugs 0.000 abstract 1
- 239000007822 coupling agent Substances 0.000 abstract 1
- 229960002069 diamorphine Drugs 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229960005181 morphine Drugs 0.000 abstract 1
- 229960000938 nalorphine Drugs 0.000 abstract 1
- 229920005615 natural polymer Polymers 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 229920000656 polylysine Polymers 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 229920001059 synthetic polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3699970A | 1970-05-13 | 1970-05-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7408140L true SE7408140L (index.php) | 1974-06-19 |
| SE417970B SE417970B (sv) | 1981-04-27 |
Family
ID=21891894
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7408141A SE389739B (sv) | 1970-05-13 | 1971-05-13 | Sett att pavisa opiumalkaloider |
| SE7106271A SE389737B (sv) | 1970-05-13 | 1971-05-13 | Reagens for bestemning av opiumalkaloider innefattande en opiumalkaloidspecifik antikropp jemte sett att framstella reagenset |
| SE7408141A SE7408141L (index.php) | 1970-05-13 | 1974-06-19 | |
| SE7408140A SE417970B (sv) | 1970-05-13 | 1974-06-19 | Opiumalkaloidantigen till anvendning vid framstellning av en antikropp som kan utnyttjas vid immunanalys av opiumalkaloiden i biologisk vetska |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7408141A SE389739B (sv) | 1970-05-13 | 1971-05-13 | Sett att pavisa opiumalkaloider |
| SE7106271A SE389737B (sv) | 1970-05-13 | 1971-05-13 | Reagens for bestemning av opiumalkaloider innefattande en opiumalkaloidspecifik antikropp jemte sett att framstella reagenset |
| SE7408141A SE7408141L (index.php) | 1970-05-13 | 1974-06-19 |
Country Status (5)
| Country | Link |
|---|---|
| CA (1) | CA966778A (index.php) |
| DE (1) | DE2166716C3 (index.php) |
| DK (1) | DK142145B (index.php) |
| GB (1) | GB1320056A (index.php) |
| SE (4) | SE389739B (index.php) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4104367A (en) * | 1976-10-13 | 1978-08-01 | Hoffmann-La Roche Inc. | Radioimmunoassay for methadone |
| CN113968853B (zh) * | 2020-07-22 | 2022-09-16 | 中国农业大学 | 阿托品类生物碱的半抗原、人工抗原及其制备方法与应用 |
-
1971
- 1971-05-11 DE DE2166716A patent/DE2166716C3/de not_active Expired
- 1971-05-12 CA CA112,764A patent/CA966778A/en not_active Expired
- 1971-05-12 DK DK228271AA patent/DK142145B/da unknown
- 1971-05-13 SE SE7408141A patent/SE389739B/xx not_active IP Right Cessation
- 1971-05-13 SE SE7106271A patent/SE389737B/xx unknown
- 1971-05-13 GB GB1462971*[A patent/GB1320056A/en not_active Expired
-
1974
- 1974-06-19 SE SE7408141A patent/SE7408141L/xx unknown
- 1974-06-19 SE SE7408140A patent/SE417970B/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE2123300A1 (de) | 1971-11-25 |
| DE2166716A1 (de) | 1975-04-24 |
| CA966778A (en) | 1975-04-29 |
| DE2123300B2 (de) | 1976-03-04 |
| SE389739B (sv) | 1976-11-15 |
| DE2166716C3 (de) | 1980-06-12 |
| SE7408141L (index.php) | 1974-06-19 |
| DE2166716B2 (de) | 1979-09-27 |
| SE389737B (sv) | 1976-11-15 |
| DK142145C (index.php) | 1981-02-02 |
| SE417970B (sv) | 1981-04-27 |
| GB1320056A (en) | 1973-06-13 |
| DK142145B (da) | 1980-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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