SE521652C2 - En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein - Google Patents

En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein

Info

Publication number
SE521652C2
SE521652C2 SE0100938A SE0100938A SE521652C2 SE 521652 C2 SE521652 C2 SE 521652C2 SE 0100938 A SE0100938 A SE 0100938A SE 0100938 A SE0100938 A SE 0100938A SE 521652 C2 SE521652 C2 SE 521652C2
Authority
SE
Sweden
Prior art keywords
scca1
scca2
fusion protein
detecting
gene
Prior art date
Application number
SE0100938A
Other languages
English (en)
Swedish (sv)
Other versions
SE0100938D0 (sv
Inventor
Eva Roejer
Original Assignee
Canag Diagnostics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canag Diagnostics Ab filed Critical Canag Diagnostics Ab
Priority to SE0100938A priority Critical patent/SE521652C2/sv
Publication of SE0100938D0 publication Critical patent/SE0100938D0/xx
Priority to MXPA03007949A priority patent/MXPA03007949A/es
Priority to JP2002573898A priority patent/JP4436044B2/ja
Priority to AT02708878T priority patent/ATE409229T1/de
Priority to PCT/SE2002/000512 priority patent/WO2002074904A2/en
Priority to RU2003130370/13A priority patent/RU2288269C2/ru
Priority to ES02708878T priority patent/ES2315349T3/es
Priority to AU2002243139A priority patent/AU2002243139B2/en
Priority to BRPI0208021 priority patent/BRPI0208021B8/pt
Priority to EP02708878A priority patent/EP1368476B1/en
Priority to CA2440028A priority patent/CA2440028C/en
Priority to DE60229043T priority patent/DE60229043D1/de
Priority to US10/661,742 priority patent/US20070218463A1/en
Publication of SE521652C2 publication Critical patent/SE521652C2/sv
Priority to US12/552,557 priority patent/US8288518B2/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4731Recognins, e.g. malignin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SE0100938A 2001-03-15 2001-03-15 En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein SE521652C2 (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE0100938A SE521652C2 (sv) 2001-03-15 2001-03-15 En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein
DE60229043T DE60229043D1 (de) 2001-03-15 2002-03-15 Rearrangierte plattenepithelkarzinomantigen-gene ii
ES02708878T ES2315349T3 (es) 2001-03-15 2002-03-15 Genes ii de antigeno de carcinoma de celula escamosa reordenados.
BRPI0208021 BRPI0208021B8 (pt) 2001-03-15 2002-03-15 genes de antígeno ii de carcinoma de células escamosas rearranjados
AT02708878T ATE409229T1 (de) 2001-03-15 2002-03-15 Rearrangierte plattenepithelkarzinomantigen-gene ii
PCT/SE2002/000512 WO2002074904A2 (en) 2001-03-15 2002-03-15 Rearranged squamous cell carcinoma antigen genes ii
RU2003130370/13A RU2288269C2 (ru) 2001-03-15 2002-03-15 Слитый транскрипт реаранжированных генов scca1 и scca2, кодирующая его последовательность днк и экспрессирующая плазмида (варианты)
MXPA03007949A MXPA03007949A (es) 2001-03-15 2002-03-15 Genes ii del antigeno de carcinoma de celulas escamosas, reordenados.
AU2002243139A AU2002243139B2 (en) 2001-03-15 2002-03-15 Rearranged squamous cell carcinoma antigen genes II
JP2002573898A JP4436044B2 (ja) 2001-03-15 2002-03-15 転位した扁平上皮癌抗原遺伝子ii
EP02708878A EP1368476B1 (en) 2001-03-15 2002-03-15 Rearranged squamous cell carcinoma antigen genes ii
CA2440028A CA2440028C (en) 2001-03-15 2002-03-15 Rearranged squamous cell carcinoma antigen genes ii
US10/661,742 US20070218463A1 (en) 2001-03-15 2003-09-12 Rearranged squamous cell carcinoma antigen genes II
US12/552,557 US8288518B2 (en) 2001-03-15 2009-09-02 Rearranged squamous cell carcinoma antigen genes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0100938A SE521652C2 (sv) 2001-03-15 2001-03-15 En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein

Publications (2)

Publication Number Publication Date
SE0100938D0 SE0100938D0 (sv) 2001-03-15
SE521652C2 true SE521652C2 (sv) 2003-11-25

Family

ID=20283412

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0100938A SE521652C2 (sv) 2001-03-15 2001-03-15 En skivepitelcellcancerrelaterad fusionsgen och motsvarande fusionsprotein

Country Status (13)

Country Link
US (2) US20070218463A1 (ja)
EP (1) EP1368476B1 (ja)
JP (1) JP4436044B2 (ja)
AT (1) ATE409229T1 (ja)
AU (1) AU2002243139B2 (ja)
BR (1) BRPI0208021B8 (ja)
CA (1) CA2440028C (ja)
DE (1) DE60229043D1 (ja)
ES (1) ES2315349T3 (ja)
MX (1) MXPA03007949A (ja)
RU (1) RU2288269C2 (ja)
SE (1) SE521652C2 (ja)
WO (1) WO2002074904A2 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0202702L (sv) * 2002-09-10 2004-05-10 Canag Diagnostics Ab Immunotest för specifik bestämning av SCCA isoformer
BRPI0410979A (pt) 2003-09-18 2006-07-04 Axys Pharm Inc composto, composição farmacêutica, e, métodos para tratar uma doença em um animal mediada pela catepsina s e para tratar um paciente submetido a uma terapia
DE10360456A1 (de) * 2003-12-22 2005-07-28 Vaecgene Biotech Gmbh Tumorantigene und deren Verwendung
NZ561681A (en) 2005-03-21 2011-01-28 Virobay Inc Alpha ketoamide compounds as cysteine protease inhibitors
JP5215167B2 (ja) 2005-03-22 2013-06-19 ビロベイ,インコーポレイティド システインプロテアーゼ阻害剤としてのスルホニル基含有化合物
DK2079683T3 (en) 2006-10-04 2015-04-27 Virobay Inc Difluoro-containing compounds as cysteine protease inhibitors
US7893112B2 (en) 2006-10-04 2011-02-22 Virobay, Inc. Di-fluoro containing compounds as cysteine protease inhibitors
US8324417B2 (en) 2009-08-19 2012-12-04 Virobay, Inc. Process for the preparation of (S)-2-amino-5-cyclopropyl-4,4-difluoropentanoic acid and alkyl esters and acid salts thereof
CN112280746A (zh) * 2020-10-29 2021-01-29 杭州华葵金配生物科技有限公司 一种细胞癌抗原杂交瘤细胞株及其单克隆抗体的应用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2044421C (en) * 1990-11-27 2005-06-21 Thomas Hyatt Duffy Squamous cell carcinoma-like immunoreactive antigen from human female urine
DE19742725A1 (de) * 1997-09-26 1999-04-01 Abts Harry Frank Dr Hurpin/PI13: Ein neuer, UV-reprimierbarer, Serin Protease Inhibitor aus der Familie der Ovalbumin-Serpine
WO2001002603A1 (en) * 1999-06-30 2001-01-11 Jakob Stenman Diagnostic method for squamous cell carcinoma

Also Published As

Publication number Publication date
ES2315349T3 (es) 2009-04-01
EP1368476B1 (en) 2008-09-24
AU2002243139B2 (en) 2007-02-01
MXPA03007949A (es) 2004-10-15
US20070218463A1 (en) 2007-09-20
JP4436044B2 (ja) 2010-03-24
WO2002074904A3 (en) 2002-11-14
SE0100938D0 (sv) 2001-03-15
JP2004529634A (ja) 2004-09-30
BR0208021A (pt) 2004-02-25
WO2002074904A2 (en) 2002-09-26
CA2440028A1 (en) 2002-09-26
CA2440028C (en) 2013-06-18
US20100062514A1 (en) 2010-03-11
BRPI0208021B8 (pt) 2021-05-25
ATE409229T1 (de) 2008-10-15
BRPI0208021B1 (pt) 2018-12-04
RU2003130370A (ru) 2005-01-20
RU2288269C2 (ru) 2006-11-27
DE60229043D1 (de) 2008-11-06
US8288518B2 (en) 2012-10-16
EP1368476A2 (en) 2003-12-10

Similar Documents

Publication Publication Date Title
US8288518B2 (en) Rearranged squamous cell carcinoma antigen genes
CA2457065A1 (en) Periostin-based diagnostic assays
AU2002243139A1 (en) Rearranged squamous cell carcinoma antigen genes II
CA2498524C (en) Immunoassays for specific determination of scca isoforms
EP3746791B1 (en) Use of bmmf1 rep protein as biomarker for colorectal cancer
US20080057520A1 (en) Immunoassays for specific determination of scca isoforms
EP3699594A1 (en) Use of bmmf1 rep protein as a biomarker for prostate cancer
US20220034890A1 (en) Use of bmmf1 rep protein as a biomarker for breast cancer
Röijer et al. Rearrangement of squamous cell carcinoma antigen genes–detection of SCCA fusion transcripts
KR20140041435A (ko) 항il28b 항체 및 이것을 사용한 il28b의 측정 방법
CN109776679B (zh) 一种丝氨酸蛋白酶抑制因子spink1的抗体、其制备方法和应用
US9200262B2 (en) Method for the diagnosis of the presence of an ovarian cancer
EP0428518A1 (en) Monoclonal antibodies specific for the harvey, kirsten and n ras proteins and their use as diagnostic reagents
KR20120058678A (ko) 인간 tesc 단백질에 특이적으로 결합하는 단일클론항체 및 이의 용도
KR20010087684A (ko) 신경펩타이드 유로코틴에 대한 단일클론 항체, 이를분비하는 세포주 및 그의 제조방법
TW201016232A (en) An antigen polypeptide for the diagnosis and/or treatment of ovarian cancer

Legal Events

Date Code Title Description
NUG Patent has lapsed