SE470261B - Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering - Google Patents

Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering

Info

Publication number
SE470261B
SE470261B SE8402662A SE8402662A SE470261B SE 470261 B SE470261 B SE 470261B SE 8402662 A SE8402662 A SE 8402662A SE 8402662 A SE8402662 A SE 8402662A SE 470261 B SE470261 B SE 470261B
Authority
SE
Sweden
Prior art keywords
adsorbent
proteins
adsorption
solid phase
immobilization
Prior art date
Application number
SE8402662A
Other languages
English (en)
Swedish (sv)
Other versions
SE8402662D0 (sv
SE8402662L (sv
Inventor
Jerker Porath
Original Assignee
Jerker Porath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jerker Porath filed Critical Jerker Porath
Priority to SE8402662A priority Critical patent/SE470261B/sv
Publication of SE8402662D0 publication Critical patent/SE8402662D0/xx
Priority to EP85850148A priority patent/EP0165912B1/fr
Priority to DE8585850148T priority patent/DE3575872D1/de
Priority to JP60105768A priority patent/JPS615099A/ja
Publication of SE8402662L publication Critical patent/SE8402662L/
Publication of SE470261B publication Critical patent/SE470261B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • B01J20/3282—Crosslinked polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
SE8402662A 1984-05-17 1984-05-17 Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering SE470261B (sv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE8402662A SE470261B (sv) 1984-05-17 1984-05-17 Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering
EP85850148A EP0165912B1 (fr) 1984-05-17 1985-04-29 Adsorbant à base de thioéther pour la séparation de protéines et analogues
DE8585850148T DE3575872D1 (de) 1984-05-17 1985-04-29 Thioether-sorbentmittel fuer die trennung von proteinen und dergleichen.
JP60105768A JPS615099A (ja) 1984-05-17 1985-05-17 蛋白質等の分離用チオエ−テル吸着剤およびその製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8402662A SE470261B (sv) 1984-05-17 1984-05-17 Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering

Publications (3)

Publication Number Publication Date
SE8402662D0 SE8402662D0 (sv) 1984-05-17
SE8402662L SE8402662L (sv) 1985-11-18
SE470261B true SE470261B (sv) 1993-12-20

Family

ID=20355913

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8402662A SE470261B (sv) 1984-05-17 1984-05-17 Adsorbent för separation och immobilisering av proteiner, sätt att framställa ett adsorbent, samt dess användning för biopolymer fraktionering

Country Status (4)

Country Link
EP (1) EP0165912B1 (fr)
JP (1) JPS615099A (fr)
DE (1) DE3575872D1 (fr)
SE (1) SE470261B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE462165B (sv) * 1988-02-26 1990-05-14 Porath Jerker Saett att paa en baerare adsorbera sammansatta proteinkomplex, saerskilt vid biospecifika bestaemningsmetoder
US5071819A (en) * 1988-08-26 1991-12-10 Ibc Advanced Technologies Sulfur and nitrogen-containing hydrocarbons and process of using same in recovering and concentrating desired ions from solutions thereof
US5149425A (en) * 1988-11-09 1992-09-22 Chembiomed, Ltd. Affinity supports for hemoperfusion
US5240601A (en) * 1988-11-09 1993-08-31 Chembiomed, Ltd. Affinity supports for hemoperfusion
EP0460026A1 (fr) * 1989-02-21 1991-12-11 Eastman Kodak Company Colonne de chromatographie par affinite a haute performance comprenant un materiau de garniture polymere non poreux, monodisperse
JPH0750086B2 (ja) * 1989-09-13 1995-05-31 ダイソー株式会社 クロマトグラフ充填剤及びこれによる水溶性有機化合物の分離法
DK52791D0 (da) * 1991-03-22 1991-03-22 Kem En Tec As Adsorptionsmatricer
DE4310964A1 (de) * 1992-04-16 1993-10-21 Merck Patent Gmbh Aktivierte Trägermaterialien, ihre Herstellung und Verwendung
US5502022A (en) * 1994-05-16 1996-03-26 Biosepra, Inc. Chromatography adsorbents utilizing mercapto heterocyclic ligands
US5789578A (en) * 1996-01-11 1998-08-04 Massey University Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality
DE19623131C2 (de) * 1996-06-10 2001-10-31 Gerhard Harry Scholz Konjugat, Verfahren zu dessen Herstellung sowie dessen Verwendung zur Bindung von Substanzen
CA2264177C (fr) 1996-08-30 2015-03-17 Upfront Chromatography A/S Isolement d'immunoglobulines
SE9700769D0 (sv) 1997-03-04 1997-03-04 Pharmacia Biotech Ab Matriser för separation och separation som utnyttjar matriserna
GB0219681D0 (en) * 2002-08-23 2002-10-02 Anglo Platinum Ltd Chromatographic medium
US7144743B2 (en) 2002-09-13 2006-12-05 Pall Corporation Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
DE10313324A1 (de) * 2003-03-25 2004-10-21 Instraction Gmbh Verfahren zur selektiven Bindung eines Substrats an Sorbentien durch mindestens bivalente Bindung
US8021889B2 (en) 2004-01-20 2011-09-20 Pall Corporation Chromatographic material for the absorption of proteins at physiological ionic strength
EP1754534A1 (fr) 2005-08-03 2007-02-21 MERCK PATENT GmbH Polymère hydrophile réticulé
EP3297757B1 (fr) 2015-05-22 2020-07-15 Merck Patent GmbH Colonne chromatographique et son utilisation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2319495C2 (de) * 1973-04-17 1985-01-10 Yeda Research And Development Co., Ltd., Rehovot Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule
LU73094A1 (fr) * 1975-07-29 1977-03-24
US4111838A (en) * 1977-09-09 1978-09-05 Eastman Kodak Company Composition for chromatography
GB2092470B (en) * 1981-02-10 1984-07-18 Tanabe Seiyaku Co Method for reducing the pyrogen content of or removing pyrogens from solutions contaminated therewith

Also Published As

Publication number Publication date
SE8402662D0 (sv) 1984-05-17
EP0165912A3 (en) 1987-01-28
EP0165912B1 (fr) 1990-02-07
SE8402662L (sv) 1985-11-18
JPS615099A (ja) 1986-01-10
JPH059440B2 (fr) 1993-02-04
DE3575872D1 (de) 1990-03-15
EP0165912A2 (fr) 1985-12-27

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