SE462829B - Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas - Google Patents
Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinasInfo
- Publication number
- SE462829B SE462829B SE8900067A SE8900067A SE462829B SE 462829 B SE462829 B SE 462829B SE 8900067 A SE8900067 A SE 8900067A SE 8900067 A SE8900067 A SE 8900067A SE 462829 B SE462829 B SE 462829B
- Authority
- SE
- Sweden
- Prior art keywords
- modified
- domain
- normal human
- active composition
- component
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/49—Urokinase; Tissue plasminogen activator
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- A61K38/166—Streptokinase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8900067A SE462829B (sv) | 1989-01-10 | 1989-01-10 | Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas |
US07/459,210 US5202121A (en) | 1989-01-10 | 1989-12-29 | Thrombolytic compositions |
CA002007075A CA2007075C (en) | 1989-01-10 | 1990-01-03 | New thrombolytic compositions |
EP90850008A EP0381640B1 (en) | 1989-01-10 | 1990-01-08 | New thrombolytic compositions |
DK90850008.5T DK0381640T3 (da) | 1989-01-10 | 1990-01-08 | Thrombolytiske præparater |
AU47768/90A AU624466B2 (en) | 1989-01-10 | 1990-01-08 | New thrombolytic compositions |
DE9090850008T DE69000290T2 (de) | 1989-01-10 | 1990-01-08 | Thrombotische zusammensetzungen. |
AT90850008T ATE80308T1 (de) | 1989-01-10 | 1990-01-08 | Thrombotische zusammensetzungen. |
ES90850008T ES2044534T3 (es) | 1989-01-10 | 1990-01-08 | Un metodo para la preparacion de una composicion tromboliticamente activa. |
JP2001149A JP2958650B2 (ja) | 1989-01-10 | 1990-01-09 | 新規な血栓溶解組成物 |
GR920402378T GR3006053T3 (ja) | 1989-01-10 | 1992-10-22 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8900067A SE462829B (sv) | 1989-01-10 | 1989-01-10 | Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8900067D0 SE8900067D0 (sv) | 1989-01-10 |
SE462829B true SE462829B (sv) | 1990-09-10 |
Family
ID=20374707
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8900067A SE462829B (sv) | 1989-01-10 | 1989-01-10 | Trombolytiskt aktiva kompositioner innehaallande en modifierad plasminogenaktivator av vaevnadstyp samt en normal human t-pa, streptokinas eller humant urokinas |
Country Status (11)
Country | Link |
---|---|
US (1) | US5202121A (ja) |
EP (1) | EP0381640B1 (ja) |
JP (1) | JP2958650B2 (ja) |
AT (1) | ATE80308T1 (ja) |
AU (1) | AU624466B2 (ja) |
CA (1) | CA2007075C (ja) |
DE (1) | DE69000290T2 (ja) |
DK (1) | DK0381640T3 (ja) |
ES (1) | ES2044534T3 (ja) |
GR (1) | GR3006053T3 (ja) |
SE (1) | SE462829B (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6682733B1 (en) * | 1987-06-18 | 2004-01-27 | Roche Diagnostics, Gmbh | Fibrinolytic enzymes |
GB8919803D0 (en) * | 1989-09-01 | 1989-10-18 | Ciba Geigy | Pharmaceutical compositions |
US6020181A (en) * | 1995-05-17 | 2000-02-01 | New York Blood, Inc. | Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase |
US5830468A (en) * | 1995-05-17 | 1998-11-03 | The New York Blood Center, Inc. | Fibrin(ogen) degradation by fibrinolytic matrix metalloproteinase |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8503097A (nl) * | 1985-11-11 | 1987-06-01 | Leuven Res & Dev Vzw | Geneesmiddel met thrombolytische werking. |
DE3789664T3 (de) * | 1986-01-31 | 2004-09-16 | Genetics Institute, LLC, Cambridge | Neue thrombolytische proteine. |
PT84589B (en) * | 1986-04-02 | 1989-05-09 | Beecham Group Plc | Process for preparing a fibrinolytic enzyme |
NL8701021A (nl) * | 1987-04-29 | 1988-11-16 | Stichting Centraal Lab | Humane t-pa(u-pa) substitutie-mutant eiwitten, daarvoor coderend recombinant dna, getransfecteerde gastheercellen, bereiding van de mutant eiwitten, en farmaceutische preparaten. |
US4935237A (en) * | 1988-03-21 | 1990-06-19 | Genentech, Inc. | Processes for the preparation of t-PA mutants |
US4963357A (en) * | 1987-10-09 | 1990-10-16 | Monsanto Company | Tissue plasminogen activator modified by the substitution of Arg for Cys at position 73, methods and pharmaceutical compositions therefor |
DE3741149A1 (de) * | 1987-12-04 | 1989-06-15 | Thomae Gmbh Dr K | Zubereitungsformen zur verhinderung von adhaesionen von organen und organteilen |
-
1989
- 1989-01-10 SE SE8900067A patent/SE462829B/sv not_active IP Right Cessation
- 1989-12-29 US US07/459,210 patent/US5202121A/en not_active Expired - Lifetime
-
1990
- 1990-01-03 CA CA002007075A patent/CA2007075C/en not_active Expired - Fee Related
- 1990-01-08 AU AU47768/90A patent/AU624466B2/en not_active Ceased
- 1990-01-08 EP EP90850008A patent/EP0381640B1/en not_active Expired - Lifetime
- 1990-01-08 DK DK90850008.5T patent/DK0381640T3/da active
- 1990-01-08 DE DE9090850008T patent/DE69000290T2/de not_active Expired - Fee Related
- 1990-01-08 AT AT90850008T patent/ATE80308T1/de not_active IP Right Cessation
- 1990-01-08 ES ES90850008T patent/ES2044534T3/es not_active Expired - Lifetime
- 1990-01-09 JP JP2001149A patent/JP2958650B2/ja not_active Expired - Fee Related
-
1992
- 1992-10-22 GR GR920402378T patent/GR3006053T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU4776890A (en) | 1990-08-30 |
US5202121A (en) | 1993-04-13 |
EP0381640B1 (en) | 1992-09-09 |
EP0381640A1 (en) | 1990-08-08 |
DK0381640T3 (da) | 1992-12-21 |
AU624466B2 (en) | 1992-06-11 |
ES2044534T3 (es) | 1994-01-01 |
DE69000290D1 (de) | 1992-10-15 |
JPH02225420A (ja) | 1990-09-07 |
DE69000290T2 (de) | 1993-04-22 |
JP2958650B2 (ja) | 1999-10-06 |
SE8900067D0 (sv) | 1989-01-10 |
GR3006053T3 (ja) | 1993-06-21 |
ATE80308T1 (de) | 1992-09-15 |
CA2007075A1 (en) | 1990-07-10 |
CA2007075C (en) | 2002-03-19 |
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