SE435927B - Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan - Google Patents

Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan

Info

Publication number
SE435927B
SE435927B SE8000085A SE8000085A SE435927B SE 435927 B SE435927 B SE 435927B SE 8000085 A SE8000085 A SE 8000085A SE 8000085 A SE8000085 A SE 8000085A SE 435927 B SE435927 B SE 435927B
Authority
SE
Sweden
Prior art keywords
trans
ethyl
pyrrolidinol
chlorophenoxy
therapeutic effect
Prior art date
Application number
SE8000085A
Other languages
English (en)
Swedish (sv)
Other versions
SE8000085L (sv
Inventor
D A Walsh
Jr W J Welstead
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of SE8000085L publication Critical patent/SE8000085L/xx
Publication of SE435927B publication Critical patent/SE435927B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/20Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
SE8000085A 1979-01-09 1980-01-07 Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan SE435927B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US215179A 1979-01-09 1979-01-09

Publications (2)

Publication Number Publication Date
SE8000085L SE8000085L (sv) 1980-08-26
SE435927B true SE435927B (sv) 1984-10-29

Family

ID=21699450

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8000085A SE435927B (sv) 1979-01-09 1980-01-07 Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan

Country Status (9)

Country Link
JP (1) JPS5598160A (fr)
CA (1) CA1133495A (fr)
CH (1) CH643243A5 (fr)
DE (1) DE3000625A1 (fr)
FR (1) FR2446279B1 (fr)
GB (1) GB2040933B (fr)
IT (1) IT1127967B (fr)
MX (1) MX6634E (fr)
SE (1) SE435927B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45511B1 (en) 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US4547514A (en) * 1983-12-05 1985-10-15 A. H. Robins Company, Incorporated Aryloxy-N-(aminoalkyl)-1-pyrrolidine and piperidine carboxamides and carbothioamides having antiarrhythmic activity
JPS60178860A (ja) * 1984-02-24 1985-09-12 Sankyo Co Ltd 3−メルカプトピロリジンまたはその塩の製法
JPS6157552A (ja) * 1984-08-29 1986-03-24 Toyama Chem Co Ltd 3−アミノピロリジンまたはその塩の製法
DE3813416A1 (de) * 1988-04-21 1989-11-02 Hoechst Ag 3,4-dihydroxypyrrolidin-2-on-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung sowie die bei der herstellung anfallenden neuen zwischenprodukte
EP0407701A3 (en) * 1989-05-15 1992-04-22 Fujisawa Pharmaceutical Co., Ltd. Antiretroviral pyrroline and pyrrolidine sulfonic acid derivatives
WO2008150470A1 (fr) 2007-05-31 2008-12-11 Shionogi & Co., Ltd. Composés d'oximes et leur utilisation
US8518934B2 (en) 2008-06-11 2013-08-27 Shonogi & Co., Ltd. Oxycarbamoyl compounds and the use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1000308A (fr) * 1949-05-28 1952-02-11 Basf Ag Procédé pour la production de 3. 4-dioxypyrrolidines
FR1000310A (fr) * 1949-06-18 1952-02-11 Basf Ag Procédé pour la production de dérivés de pyrrolidine
FR1532221A (fr) * 1963-10-22 1968-07-12 Robins Co Inc A H Procédé de production de n, n-di (aryl monocarbocyclique)-carbamates de 1-(alkylinférieur)-3-pyrrolidyle
CH521338A (de) * 1967-03-13 1972-04-15 Robins Co Inc A H Verfahren zur Herstellung von neuen Pyrrolidinderivaten
US3577415A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-substituted phenoxypyrrolidines
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof

Also Published As

Publication number Publication date
DE3000625A1 (de) 1980-07-17
CH643243A5 (fr) 1984-05-30
JPS5598160A (en) 1980-07-25
MX6634E (es) 1985-09-12
GB2040933B (en) 1983-07-20
IT8067020A0 (it) 1980-01-08
CA1133495A (fr) 1982-10-12
GB2040933A (en) 1980-09-03
FR2446279B1 (fr) 1985-10-31
IT1127967B (it) 1986-05-28
SE8000085L (sv) 1980-08-26
JPS648621B2 (fr) 1989-02-14
DE3000625C2 (fr) 1989-04-20
FR2446279A1 (fr) 1980-08-08

Similar Documents

Publication Publication Date Title
NO163618B (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aryloksy- og aryltio-hydroksypropyl-piperazin-acetanilider.
HU193161B (en) Process for preparing new n-alkyl-norscopines
US4381398A (en) Amino-alcohol derivatives
SE435927B (sv) Trans-4-(2-klorofenoxi)-1-etyl-pyrrolidinol med terapeutisk verkan
EP0104614B1 (fr) Dérivés du phénylpipérazine et leur procédé de préparation
US3825558A (en) Substituted aminopropoxy-2-indolinones
CS219944B2 (en) Method of making the racemic and optically unite derivatives of the 1-phenyl-2-cyclohexen-1-alkylamine
EP0373593B1 (fr) Acyloxypropanolamines
EP0520435A2 (fr) Dérivés du composé DC 89
CH668973A5 (de) Purin-derivate, ihre herstellung und sie enthaltende arzneimittel.
US4942143A (en) Imidazothiadiazine derivatives, and their use as medicaments
EP0011747B1 (fr) Dérivés aminopropanols de 6-hydroxy-2,3,4,5-tétrahydro-1H-1-benzazépin-2-ones, procédé pour leur préparation, et compositions pharmaceutiques les contenant
EP0230020A2 (fr) 1,2,3,4,4a,9b-Hexahydro-4a-aminoalkyldibenzofurannes, procédé pour leur préparation et leur utilisation comme médicaments
EP0333938B1 (fr) Dérivés de l'hydroxy-2 aryloxy-3 propylamine à activité cardiovasculaire
SE450704B (sv) 3,7-diazabicyklo /3,3,1/ nonaner, forfarande for framstellning och farmaceutisk beredning derav
DE69223422T2 (de) Benzothiadiazinderivate
Ferrarini et al. Stereoselective synthesis and β-blocking activity of substituted (E)-and (Z)-4 (1H)-[1-(3-alkylamino-2-hydroxypropyl) oximino]-2, 3-dihydro-1, 8-naphthyridine. Potential antihypertensive agents. Part VI
HU187600B (en) Process for preparing 2-methyl-9,10-didehydro-ergolines
US3988371A (en) Meta-[2-(benzylamino)-ethyl] benzoic acid amides
US3373163A (en) N-methyl-piperazides of alicyclic and heterocyclic carboxylic acids
US20120059053A1 (en) Compounds of 2,3-dihydro-benzofuran
CA1181755A (fr) Procede d'obtention de derives d'alkylene-diamine
JPS648620B2 (fr)
HU176675B (en) Process for preparing substituted sulphoximides and pharmaceutical nreparations containing such active material
SE460419B (sv) Substituerade 1-pyridyloxi-3-indolylalkylamino-2-propanoler, foerfarande foer framstaellning av dessa och en farmaceutisk komposition

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8000085-4

Effective date: 19920806

Format of ref document f/p: F