SE435634B - Glykos-isomeriserande enzym, forfarande for framstellning derav genom odling av flavobacterium arborescens och anvendning av enzymet for konvertering av glukos till fruktos - Google Patents
Glykos-isomeriserande enzym, forfarande for framstellning derav genom odling av flavobacterium arborescens och anvendning av enzymet for konvertering av glukos till fruktosInfo
- Publication number
- SE435634B SE435634B SE7711054A SE7711054A SE435634B SE 435634 B SE435634 B SE 435634B SE 7711054 A SE7711054 A SE 7711054A SE 7711054 A SE7711054 A SE 7711054A SE 435634 B SE435634 B SE 435634B
- Authority
- SE
- Sweden
- Prior art keywords
- enzyme
- glucose
- fructose
- nrrl
- flavobacterium
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims description 26
- 239000008103 glucose Substances 0.000 title claims description 25
- 102000004190 Enzymes Human genes 0.000 title claims description 22
- 108090000790 Enzymes Proteins 0.000 title claims description 22
- 229930091371 Fructose Natural products 0.000 title claims description 16
- 239000005715 Fructose Substances 0.000 title claims description 16
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 title claims description 16
- 238000000034 method Methods 0.000 title claims description 10
- 238000006243 chemical reaction Methods 0.000 title claims description 6
- 241000589565 Flavobacterium Species 0.000 title claims description 3
- 230000000694 effects Effects 0.000 claims description 25
- 244000005700 microbiome Species 0.000 claims description 10
- 235000015097 nutrients Nutrition 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 5
- 241001467579 Microbacterium arborescens Species 0.000 claims description 4
- 230000001413 cellular effect Effects 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims description 2
- 239000000463 material Substances 0.000 claims description 2
- 238000011084 recovery Methods 0.000 claims 1
- 108090000769 Isomerases Proteins 0.000 description 26
- 102000004195 Isomerases Human genes 0.000 description 26
- 239000002609 medium Substances 0.000 description 13
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 12
- 239000000243 solution Substances 0.000 description 11
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 10
- 240000004320 Fuchsia arborescens Species 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 9
- 239000008101 lactose Substances 0.000 description 9
- 239000006188 syrup Substances 0.000 description 7
- 235000020357 syrup Nutrition 0.000 description 7
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 6
- 150000001720 carbohydrates Chemical class 0.000 description 6
- 235000014633 carbohydrates Nutrition 0.000 description 6
- 238000006317 isomerization reaction Methods 0.000 description 6
- 229910001629 magnesium chloride Inorganic materials 0.000 description 6
- 238000011534 incubation Methods 0.000 description 5
- 238000004458 analytical method Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 3
- 235000021120 animal protein Nutrition 0.000 description 3
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 3
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 229940041514 candida albicans extract Drugs 0.000 description 3
- 238000012258 culturing Methods 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 239000002054 inoculum Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 238000003756 stirring Methods 0.000 description 3
- 239000012138 yeast extract Substances 0.000 description 3
- OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 2
- SEQKRHFRPICQDD-UHFFFAOYSA-N N-tris(hydroxymethyl)methylglycine Chemical compound OCC(CO)(CO)[NH2+]CC([O-])=O SEQKRHFRPICQDD-UHFFFAOYSA-N 0.000 description 2
- 229920002472 Starch Polymers 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- 239000007997 Tricine buffer Substances 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 2
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 2
- 235000019797 dipotassium phosphate Nutrition 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 description 2
- 230000000737 periodic effect Effects 0.000 description 2
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 2
- 238000012289 standard assay Methods 0.000 description 2
- 239000008107 starch Substances 0.000 description 2
- 235000019698 starch Nutrition 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- 241000364057 Peoria Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 1
- 241000736110 Sphingomonas paucimobilis Species 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- UZMAPBJVXOGOFT-UHFFFAOYSA-N Syringetin Natural products COC1=C(O)C(OC)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UZMAPBJVXOGOFT-UHFFFAOYSA-N 0.000 description 1
- 108700040099 Xylose isomerases Proteins 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QUYVBRFLSA-N beta-maltose Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O GUBGYTABKSRVRQ-QUYVBRFLSA-N 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000010924 continuous production Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- KCFYHBSOLOXZIF-UHFFFAOYSA-N dihydrochrysin Natural products COC1=C(O)C(OC)=CC(C2OC3=CC(O)=CC(O)=C3C(=O)C2)=C1 KCFYHBSOLOXZIF-UHFFFAOYSA-N 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical class C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229960005141 piperazine Drugs 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000012134 supernatant fraction Substances 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 229920001221 xylan Polymers 0.000 description 1
- 150000004823 xylans Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
- C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/85—Flavobacterium
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/734,222 US4061539A (en) | 1976-10-20 | 1976-10-20 | Preparation and use of glucose isomerase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7711054L SE7711054L (sv) | 1978-04-21 |
| SE435634B true SE435634B (sv) | 1984-10-08 |
Family
ID=24950789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7711054A SE435634B (sv) | 1976-10-20 | 1977-10-03 | Glykos-isomeriserande enzym, forfarande for framstellning derav genom odling av flavobacterium arborescens och anvendning av enzymet for konvertering av glukos till fruktos |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US4061539A (ro) |
| JP (1) | JPS5820269B2 (ro) |
| AR (1) | AR218040A1 (ro) |
| AT (1) | AT359023B (ro) |
| AU (1) | AU510174B2 (ro) |
| BE (1) | BE859830A (ro) |
| BG (2) | BG33588A3 (ro) |
| BR (1) | BR7706944A (ro) |
| CA (1) | CA1107209A (ro) |
| CH (2) | CH630116A5 (ro) |
| DE (1) | DE2746939C2 (ro) |
| DK (1) | DK143947C (ro) |
| ES (1) | ES463344A1 (ro) |
| FI (1) | FI58939C (ro) |
| FR (1) | FR2368538A1 (ro) |
| GB (1) | GB1551897A (ro) |
| GR (1) | GR70082B (ro) |
| IL (1) | IL53095A (ro) |
| IT (1) | IT1086910B (ro) |
| LU (1) | LU78355A1 (ro) |
| NL (1) | NL176871C (ro) |
| NO (1) | NO148297C (ro) |
| NZ (1) | NZ185334A (ro) |
| PL (1) | PL110770B1 (ro) |
| PT (1) | PT67162B (ro) |
| RO (1) | RO73285A (ro) |
| SE (1) | SE435634B (ro) |
| SU (2) | SU747436A3 (ro) |
| TR (1) | TR19534A (ro) |
| YU (1) | YU40173B (ro) |
| ZA (1) | ZA775921B (ro) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399222A (en) * | 1979-08-06 | 1983-08-16 | A. E. Staley Manufacturing Company | Carbohydrases from acidophilic streptomyces |
| US4459354A (en) * | 1979-08-06 | 1984-07-10 | A. E. Staley Manufacturing Company | Carbohydrases from acidophilic streptomyces |
| US4348481A (en) * | 1979-11-29 | 1982-09-07 | Institute Po Microbiologia | Method of obtaining glucose isomerase |
| US4348480A (en) * | 1980-06-04 | 1982-09-07 | Miles Laboratories, Inc. | Process for producing glucose isomerase |
| US4317883A (en) * | 1980-12-03 | 1982-03-02 | Institute Po Microbiologia | Method for obtaining of glucose isomerase |
| US4429044A (en) | 1982-09-28 | 1984-01-31 | Miles Laboratories, Inc. | Preparation of an alkaline protease from flavobacterium arborescens |
| US4920052A (en) * | 1988-02-05 | 1990-04-24 | Miles Inc. | Process for producing glucose isomerase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5311929B2 (ro) * | 1972-08-31 | 1978-04-25 | ||
| US3834988A (en) * | 1972-10-10 | 1974-09-10 | Anheuser Busch | Method of making glucose isomerase and using same to convert glucose to fructose |
| GB1455993A (en) * | 1973-01-12 | 1976-11-17 | Novo Industri As | Glucose isomerase |
| US3956066A (en) * | 1973-08-16 | 1976-05-11 | A. E. Staley Manufacturing Company | Glucose isomerizing enzyme |
-
1976
- 1976-10-20 US US05/734,222 patent/US4061539A/en not_active Expired - Lifetime
-
1977
- 1977-10-03 SE SE7711054A patent/SE435634B/sv not_active IP Right Cessation
- 1977-10-04 NZ NZ185334A patent/NZ185334A/xx unknown
- 1977-10-04 ZA ZA00775921A patent/ZA775921B/xx unknown
- 1977-10-10 YU YU2439/77A patent/YU40173B/xx unknown
- 1977-10-10 GB GB42135/77A patent/GB1551897A/en not_active Expired
- 1977-10-10 IL IL53095A patent/IL53095A/xx unknown
- 1977-10-11 FI FI773006A patent/FI58939C/fi not_active IP Right Cessation
- 1977-10-12 AR AR269560A patent/AR218040A1/es active
- 1977-10-12 AU AU29603/77A patent/AU510174B2/en not_active Expired
- 1977-10-13 CA CA288,604A patent/CA1107209A/en not_active Expired
- 1977-10-14 GR GR54577A patent/GR70082B/el unknown
- 1977-10-17 FR FR7731190A patent/FR2368538A1/fr active Granted
- 1977-10-17 DE DE2746939A patent/DE2746939C2/de not_active Expired
- 1977-10-17 PT PT67162A patent/PT67162B/pt unknown
- 1977-10-17 RO RO7791859A patent/RO73285A/ro unknown
- 1977-10-18 BG BG037603A patent/BG33588A3/xx unknown
- 1977-10-18 BE BE1008451A patent/BE859830A/xx not_active IP Right Cessation
- 1977-10-18 BR BR7706944A patent/BR7706944A/pt unknown
- 1977-10-18 BG BG038882A patent/BG33589A3/xx unknown
- 1977-10-18 IT IT28750/77A patent/IT1086910B/it active
- 1977-10-19 CH CH1274177A patent/CH630116A5/fr not_active IP Right Cessation
- 1977-10-19 SU SU772540996A patent/SU747436A3/ru active
- 1977-10-19 DK DK464777A patent/DK143947C/da not_active IP Right Cessation
- 1977-10-19 ES ES463344A patent/ES463344A1/es not_active Expired
- 1977-10-19 TR TR19534A patent/TR19534A/xx unknown
- 1977-10-19 NO NO773591A patent/NO148297C/no unknown
- 1977-10-19 JP JP52125639A patent/JPS5820269B2/ja not_active Expired
- 1977-10-20 AT AT750677A patent/AT359023B/de not_active IP Right Cessation
- 1977-10-20 NL NLAANVRAGE7711563,A patent/NL176871C/xx not_active IP Right Cessation
- 1977-10-20 PL PL1977201627A patent/PL110770B1/pl unknown
- 1977-10-20 LU LU78355A patent/LU78355A1/xx unknown
-
1978
- 1978-02-17 SU SU782584101A patent/SU764617A3/ru active
-
1981
- 1981-10-30 CH CH692681A patent/CH635128A5/fr not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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