SE431226B - Forfarande for rening v urokinas i tre steg, varvid en vattenbaserad urokinaslosning bringas i kontakt med en katjonbytarkolonn, ett basiskt anjonbytarharts respektive en partiellt fornetad dextrangel - Google Patents

Forfarande for rening v urokinas i tre steg, varvid en vattenbaserad urokinaslosning bringas i kontakt med en katjonbytarkolonn, ett basiskt anjonbytarharts respektive en partiellt fornetad dextrangel

Info

Publication number
SE431226B
SE431226B SE7513027A SE7513027A SE431226B SE 431226 B SE431226 B SE 431226B SE 7513027 A SE7513027 A SE 7513027A SE 7513027 A SE7513027 A SE 7513027A SE 431226 B SE431226 B SE 431226B
Authority
SE
Sweden
Prior art keywords
urokinas
dextrang
partically
contacted
cleaning
Prior art date
Application number
SE7513027A
Other languages
English (en)
Other versions
SE7513027L (sv
Inventor
G A Stried
P G Sesin
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of SE7513027L publication Critical patent/SE7513027L/sv
Publication of SE431226B publication Critical patent/SE431226B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
SE7513027A 1974-11-20 1975-11-19 Forfarande for rening v urokinas i tre steg, varvid en vattenbaserad urokinaslosning bringas i kontakt med en katjonbytarkolonn, ett basiskt anjonbytarharts respektive en partiellt fornetad dextrangel SE431226B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/525,334 US3957582A (en) 1974-11-20 1974-11-20 Purification of urokinase

Publications (2)

Publication Number Publication Date
SE7513027L SE7513027L (sv) 1976-05-21
SE431226B true SE431226B (sv) 1984-01-23

Family

ID=24092806

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7513027A SE431226B (sv) 1974-11-20 1975-11-19 Forfarande for rening v urokinas i tre steg, varvid en vattenbaserad urokinaslosning bringas i kontakt med en katjonbytarkolonn, ett basiskt anjonbytarharts respektive en partiellt fornetad dextrangel

Country Status (13)

Country Link
US (1) US3957582A (sv)
JP (1) JPS5167787A (sv)
AR (1) AR208000A1 (sv)
BE (1) BE835330A (sv)
CA (1) CA1041449A (sv)
CH (1) CH608021A5 (sv)
DE (1) DE2551966C3 (sv)
DK (1) DK140555B (sv)
FR (1) FR2291983A1 (sv)
GB (1) GB1493018A (sv)
NL (1) NL162657B (sv)
SE (1) SE431226B (sv)
ZA (1) ZA756197B (sv)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS527485A (en) * 1975-07-04 1977-01-20 Asahi Chem Ind Co Ltd Isolation of urokinase
USRE29980E (en) * 1975-07-04 1979-05-01 Asahi Kasei Kogyo Kabushiki Kaisha Method of obtaining urokinase
JPS53113080A (en) * 1977-03-10 1978-10-03 Sumitomo Chem Co Ltd Purification of urokinase
DE2812609A1 (de) * 1977-04-09 1978-10-19 Tanabe Seiyaku Co Verfahren zur reinigung roher urokinase
JPS5935B2 (ja) * 1977-06-03 1984-01-05 住友化学工業株式会社 ウロキナ−ゼの精製法
FR2444465A1 (fr) * 1978-12-22 1980-07-18 Green Cross Corp Procede de production d'une preparation thrombolytique
GB2121050B (en) * 1979-07-05 1986-03-26 Genentech Inc Preparation of functional human urokinase proteins
USRE32271E (en) * 1979-11-13 1986-10-28 Isolation of plasminogen activators useful as therapeutic and diagnostic agents
AU6642281A (en) * 1979-11-13 1981-06-03 Husain, S.S. Isolation of plasminogen activators useful as therapeutic anddiagnostic agents
US4370417A (en) * 1980-04-03 1983-01-25 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator
US4558010A (en) * 1980-04-03 1985-12-10 Abbott Laboratories Recombinant deoxyribonucleic acid which codes for plasminogen activator and method of making plasminogen activator protein therefrom
US5112755A (en) * 1982-04-15 1992-05-12 Genentech, Inc. Preparation of functional human urokinase proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755083A (en) * 1971-08-30 1973-08-28 Rand Labor Inc Method for recovering urokinase from urine containing the same
FR2190413A2 (en) * 1972-06-30 1974-02-01 Choay Sa Stable,pyrogen-free urokinase prepns - from human urine
BE789189A (fr) * 1971-09-24 1973-03-22 Choay Sa Perfectionnements aux procedes de preparation, de depyrogenation et de stabilisation de l'urokinase et compositions obtenues
DE2428248B2 (de) * 1973-07-24 1978-01-12 Serna Ag, Glarus (Schweiz) Verfahren zur herstellung von pyrogenfreier urokinase
US3897309A (en) * 1974-02-15 1975-07-29 Merck & Co Inc Process for removing pyrogenic material from aqueous solutions

Also Published As

Publication number Publication date
DE2551966B2 (de) 1977-10-13
CA1041449A (en) 1978-10-31
DK140555B (da) 1979-10-01
DE2551966A1 (de) 1976-05-26
JPS5167787A (sv) 1976-06-11
US3957582A (en) 1976-05-18
AU8545075A (en) 1977-04-07
AR208000A1 (es) 1976-11-22
ZA756197B (en) 1976-09-29
DK140555C (sv) 1980-03-03
CH608021A5 (sv) 1978-12-15
NL162657B (nl) 1980-01-15
NL7511803A (nl) 1976-05-24
FR2291983A1 (fr) 1976-06-18
FR2291983B1 (sv) 1979-03-30
DE2551966C3 (de) 1978-06-01
DK521375A (sv) 1976-05-21
SE7513027L (sv) 1976-05-21
BE835330A (fr) 1976-05-07
GB1493018A (en) 1977-11-23

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