SE424184B - Forfarande for framstellning av peptider med kraftig lh-rh/fsh-rh-verkan - Google Patents

Forfarande for framstellning av peptider med kraftig lh-rh/fsh-rh-verkan

Info

Publication number
SE424184B
SE424184B SE7508926A SE7508926A SE424184B SE 424184 B SE424184 B SE 424184B SE 7508926 A SE7508926 A SE 7508926A SE 7508926 A SE7508926 A SE 7508926A SE 424184 B SE424184 B SE 424184B
Authority
SE
Sweden
Prior art keywords
fsh
powerful
procedure
effects
preparing peptides
Prior art date
Application number
SE7508926A
Other languages
English (en)
Swedish (sv)
Other versions
SE7508926L (sv
Inventor
W Konig
R Geiger
J K Sandow
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE7508926L publication Critical patent/SE7508926L/xx
Publication of SE424184B publication Critical patent/SE424184B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
SE7508926A 1974-08-09 1975-08-07 Forfarande for framstellning av peptider med kraftig lh-rh/fsh-rh-verkan SE424184B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2438350A DE2438350C3 (de) 1974-08-09 1974-08-09 Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (2)

Publication Number Publication Date
SE7508926L SE7508926L (sv) 1976-02-10
SE424184B true SE424184B (sv) 1982-07-05

Family

ID=5922833

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7508926A SE424184B (sv) 1974-08-09 1975-08-07 Forfarande for framstellning av peptider med kraftig lh-rh/fsh-rh-verkan
SE7805545A SE7805545L (cg-RX-API-DMAC7.html) 1974-08-09 1978-05-16

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7805545A SE7805545L (cg-RX-API-DMAC7.html) 1974-08-09 1978-05-16

Country Status (15)

Country Link
US (1) US4024248A (cg-RX-API-DMAC7.html)
JP (1) JPS5761268B2 (cg-RX-API-DMAC7.html)
AT (1) AT364093B (cg-RX-API-DMAC7.html)
BE (1) BE832310A (cg-RX-API-DMAC7.html)
CA (1) CA1069888A (cg-RX-API-DMAC7.html)
CH (1) CH613186A5 (cg-RX-API-DMAC7.html)
DE (1) DE2438350C3 (cg-RX-API-DMAC7.html)
DK (1) DK148905C (cg-RX-API-DMAC7.html)
FR (1) FR2281132A1 (cg-RX-API-DMAC7.html)
GB (1) GB1523623A (cg-RX-API-DMAC7.html)
IE (1) IE41510B1 (cg-RX-API-DMAC7.html)
IL (1) IL47880A (cg-RX-API-DMAC7.html)
LU (1) LU73166A1 (cg-RX-API-DMAC7.html)
NL (1) NL182051C (cg-RX-API-DMAC7.html)
SE (2) SE424184B (cg-RX-API-DMAC7.html)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2617646C2 (de) * 1976-04-22 1986-07-31 Hoechst Ag, 6230 Frankfurt Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
GB1524747A (en) * 1976-05-11 1978-09-13 Ici Ltd Polypeptide
DE2735515A1 (de) * 1977-08-06 1979-02-22 Hoechst Ag Verwendung von lh-rh-peptiden als antikonzeptive
FR2450109B1 (fr) * 1977-11-08 1986-03-28 Roussel Uclaf Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
IT1149971B (it) * 1979-06-11 1986-12-10 Syntex Inc Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
HU185535B (en) * 1982-05-25 1985-02-28 Mta Koezponti Hivatala Process for preparing new gonadoliberin derivatives
HU187503B (en) * 1983-03-29 1986-01-28 Magyar Tudomanyos Akademia,Hu Process for preparing gonadoliberine derivatives containing beta-aspartyl group
AT390066B (de) * 1983-03-29 1990-03-12 Richter Gedeon Vegyeszet Verfahren zur herstellung von neuen gonadoliberin-derivaten
DE3411224A1 (de) * 1984-03-27 1985-10-10 Hoechst Ag, 6230 Frankfurt Verfahren zur racematarmen herstellung von peptidzwischenprodukten der gonadorelin- und gonadorelinanaloga-synthese und neue zwischenprodukte bei diesem verfahren
US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4775660A (en) * 1984-08-02 1988-10-04 Fernand Labrie Treatment of breast cancer by combination therapy
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
HU194280B (en) * 1985-10-22 1988-01-28 Richter Gedeon Vegyeszet Process for producing new gonadoliberin analogues of high effectivity and pharmaceutical compositions containing them
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
AU5281990A (en) * 1989-03-10 1990-10-09 Endorecherche Inc. Combination therapy for treatment of estrogen sensitive diseases
JPH0235232A (ja) * 1989-06-29 1990-02-05 Nhk Spring Co Ltd 気室と液室を有する圧力容器
HUT60280A (en) * 1989-07-07 1992-08-28 Endorecherche Inc Process for producing androgen derivatives inhibiting sexual steroidal activity, as well as pharmaceutical compositions comprising same
JP3350048B2 (ja) * 1989-07-07 2002-11-25 アンドルシェルシュ・インコーポレイテッド アンドロゲン関連疾患の治療方法
CA2029018A1 (en) * 1989-11-01 1991-05-02 Robert P. Millar Analogues of gonadotropin releasing hormone
JPH0474770U (cg-RX-API-DMAC7.html) * 1990-10-31 1992-06-30
TW239145B (cg-RX-API-DMAC7.html) * 1992-05-21 1995-01-21 Endorech Inc
US6413536B1 (en) 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
CA2192782C (en) 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
US20060025328A1 (en) * 1997-05-28 2006-02-02 Burns Patrick J Compositions suitable for controlled release of the hormone GnRH and its analogs
US6051558A (en) * 1997-05-28 2000-04-18 Southern Biosystems, Inc. Compositions suitable for controlled release of the hormone GnRH and its analogs
US6242421B1 (en) 1997-11-06 2001-06-05 Richard Lloyd Bowen Methods for preventing and treating Alzheimer's disease
ES2154590B1 (es) 1999-05-20 2001-11-01 Lipotec Sa Procedimiento de sintesis de peptidos en fase solida
AR023940A1 (es) 2000-05-03 2002-09-04 Eriochem Sa Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua
EP1408876A4 (en) * 2001-06-22 2004-09-22 Durect Corp ZERO ORDER COAXIAL IMPLANTS WITH EXTENDED RELEASE
US20060287282A1 (en) * 2001-06-25 2006-12-21 Steiner Mitchell S Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof
JP2003137814A (ja) * 2001-08-10 2003-05-14 Takeda Chem Ind Ltd ＧｎＲＨアゴニストの併用剤
CA2466659A1 (en) 2001-11-13 2003-05-22 Takeda Chemical Industries, Ltd. Anticancer agents
US20030144203A1 (en) * 2001-12-19 2003-07-31 Voyager Pharmaceutical Corporation Methods for slowing senescence and treating and preventing diseases associated with senescence
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP2959893A1 (en) 2002-12-13 2015-12-30 DURECT Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
GB0307777D0 (en) * 2003-04-04 2003-05-07 Medical Res Council Conjugate compounds
GEP20094831B (en) * 2004-09-17 2009-11-25 Durect Corp Control release system
AU2006207325B2 (en) 2005-01-21 2012-08-16 Astex Therapeutics Limited Pharmaceutical compounds
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US8882747B2 (en) * 2005-11-09 2014-11-11 The Invention Science Fund I, Llc Substance delivery system
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8916552B2 (en) 2006-10-12 2014-12-23 Astex Therapeutics Limited Pharmaceutical combinations
EP2484347A1 (en) 2006-11-03 2012-08-08 Durect Corporation Transdermal delivery systems comprising bupivacaine
EP2219622A1 (en) 2007-12-06 2010-08-25 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
RU2444525C2 (ru) * 2010-06-09 2012-03-10 Закрытое Акционерное Общество "Фарм-Синтез" Способ получения нонапептидэтиламида и промежуточные соединения для его получения
EP2582371B1 (en) 2010-06-16 2019-10-16 Endorecherche, Inc. Methods of treating or preventing estrogen-related diseases
CN105120659A (zh) 2013-03-15 2015-12-02 度瑞公司 用于降低溶解可变性的具有流变改性剂的组合物
EP3481381B1 (en) 2016-07-06 2025-01-08 Orient Pharma Co., Ltd. Oral dosage form with drug composition, barrier layer and drug layer
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
CN116940358A (zh) 2021-01-12 2023-10-24 度勒科特公司 持续释放药物递送系统和有关的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5726506B2 (cg-RX-API-DMAC7.html) * 1974-03-08 1982-06-04
US3914412A (en) * 1973-10-11 1975-10-21 Abbott Lab {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity
US3901872A (en) * 1974-03-13 1975-08-26 American Home Prod P-glu-his-trp-ser-tyr-d-pgl-leu-arg-pro-gly-nh' 2 'and intermediates
US3896104A (en) * 1974-05-22 1975-07-22 American Home Prod P-glu-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh' 2 'and intermediates

Also Published As

Publication number Publication date
AU8374475A (en) 1977-02-10
IE41510L (en) 1976-02-09
SE7805545L (cg-RX-API-DMAC7.html) 1978-05-16
IL47880A (en) 1978-10-31
DE2438350A1 (de) 1976-02-26
CA1069888A (en) 1980-01-15
DE2438350B2 (de) 1978-10-26
NL182051C (nl) 1988-01-04
BE832310A (fr) 1976-02-11
GB1523623A (en) 1978-09-06
IL47880A0 (en) 1975-11-25
NL182051B (nl) 1987-08-03
JPS5148659A (cg-RX-API-DMAC7.html) 1976-04-26
LU73166A1 (cg-RX-API-DMAC7.html) 1977-04-13
DK148905B (da) 1985-11-11
US4024248A (en) 1977-05-17
IE41510B1 (en) 1980-01-16
DK361875A (da) 1976-02-10
AT364093B (de) 1981-09-25
SE7508926L (sv) 1976-02-10
CH613186A5 (cg-RX-API-DMAC7.html) 1979-09-14
DE2438350C3 (de) 1979-06-13
FR2281132A1 (fr) 1976-03-05
DK148905C (da) 1986-04-07
FR2281132B1 (cg-RX-API-DMAC7.html) 1979-09-14
ATA618975A (de) 1981-02-15
JPS5761268B2 (cg-RX-API-DMAC7.html) 1982-12-23
NL7509260A (nl) 1976-02-11

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