SE423633B - Forfarande for framstellning av 4-demetoxi-daunomycin - Google Patents

Forfarande for framstellning av 4-demetoxi-daunomycin

Info

Publication number
SE423633B
SE423633B SE7506589A SE7506589A SE423633B SE 423633 B SE423633 B SE 423633B SE 7506589 A SE7506589 A SE 7506589A SE 7506589 A SE7506589 A SE 7506589A SE 423633 B SE423633 B SE 423633B
Authority
SE
Sweden
Prior art keywords
demetoxy
daunomycine
preparing
procedure
Prior art date
Application number
SE7506589A
Other languages
English (en)
Swedish (sv)
Other versions
SE7506589L (sv
Inventor
B Patelli
L Bernardi
L Arcamone
Marco A Di
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE7506589L publication Critical patent/SE7506589L/xx
Publication of SE423633B publication Critical patent/SE423633B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE7506589A 1974-06-12 1975-06-09 Forfarande for framstellning av 4-demetoxi-daunomycin SE423633B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2608374A GB1467383A (en) 1974-06-12 1974-06-12 Daunomycin analogues

Publications (2)

Publication Number Publication Date
SE7506589L SE7506589L (sv) 1975-12-15
SE423633B true SE423633B (sv) 1982-05-17

Family

ID=10238087

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7506589A SE423633B (sv) 1974-06-12 1975-06-09 Forfarande for framstellning av 4-demetoxi-daunomycin

Country Status (17)

Country Link
US (1) US4046878A (nl)
JP (1) JPS5840557B2 (nl)
AT (1) AT337363B (nl)
BE (1) BE830090A (nl)
BG (1) BG61059B2 (nl)
CH (1) CH611317A5 (nl)
DE (2) DE2525633A1 (nl)
DK (1) DK147304C (nl)
ES (1) ES438431A1 (nl)
FR (1) FR2274629A1 (nl)
GB (1) GB1467383A (nl)
HK (1) HK982A (nl)
MY (1) MY103666A (nl)
NL (1) NL173272C (nl)
SE (1) SE423633B (nl)
SU (1) SU645588A3 (nl)
ZA (1) ZA753722B (nl)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1506200A (en) * 1975-04-30 1978-04-05 Farmaceutici Italia Glycosides
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
US4161480A (en) * 1978-06-05 1979-07-17 G. D. Searle & Co. Intermediates for the synthesis of 4-demethoxydaunorubicin
US4201773A (en) * 1978-07-26 1980-05-06 The United States Of America As Represented By The Department Of Health, Education And Welfare 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
IL55431A (en) * 1978-08-24 1982-07-30 Yeda Res & Dev Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) * 1979-03-17 1980-09-19 Erba Farmitalia Antitumorglycosiden.
JPS5673039A (en) * 1979-08-20 1981-06-17 Hoffmann La Roche Naphthacene derivative
EP0024727B1 (en) * 1979-09-01 1982-05-26 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, processes for their preparation and pharmaceutical composition containing them
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4348388A (en) * 1980-04-02 1982-09-07 G.D. Searle & Co. 11-Amino-11-deoxydaunorubicin and analogs
ZA814722B (en) * 1980-07-18 1982-07-28 Hoffmann La Roche Novel anthracycline glycosides
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
US4563444A (en) * 1982-05-26 1986-01-07 Farmitalia Carlo Erba S.P.A. Anthracycline glycosides, use and compositions containing same
US4604381A (en) * 1982-07-16 1986-08-05 Farmitalia Carlo Erba S.P.A. 4-demethoxy-13-dihydrodaunorubicin and use thereof
US4562177A (en) * 1982-08-17 1985-12-31 The Ohio State University Research Foundation 3'-Amino-2' halo-anthracycline antibiotics
US4564674A (en) * 1983-10-31 1986-01-14 Sagami Chemical Research Center Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
US4496485A (en) * 1983-11-25 1985-01-29 G. D. Searle & Co. Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
US4537882A (en) * 1984-05-10 1985-08-27 Ohio State University 4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4697005A (en) * 1985-03-20 1987-09-29 Ohio State University Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
JPS63191263U (nl) * 1987-05-29 1988-12-09
GB2212154B (en) * 1987-11-10 1991-03-27 Erba Carlo Spa New 4-demethoxy anthracycline derivatives
GB8803301D0 (en) * 1988-02-12 1988-03-09 Erba Carlo Spa Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) * 1988-04-11 1988-05-11 Erba Carlo Spa Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
WO1993018050A1 (en) * 1992-03-02 1993-09-16 Pfizer Inc. Sugar derivatives of macrolides
US8252520B2 (en) * 2002-10-11 2012-08-28 Taivex Therapeutics Corporation Methods and compounds for inhibiting Hec1 activity for the treatment of proliferative diseases
US20080161251A1 (en) 2005-01-21 2008-07-03 Astex Therapeutics Limited Pharmaceutical Compounds
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
EP2073807A1 (en) 2006-10-12 2009-07-01 Astex Therapeutics Limited Pharmaceutical combinations
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
NZ593648A (en) * 2008-12-23 2013-09-27 Gilead Pharmasset Llc Nucleoside phosphoramidates
CL2009002206A1 (es) * 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
EP2376514A2 (en) * 2008-12-23 2011-10-19 Pharmasset, Inc. Nucleoside analogs
BR112012012160B1 (pt) 2009-11-13 2022-04-26 Amgen, Inc. Material e métodos para tratar ou prevenir doenças associadas ao her-3
KR101715981B1 (ko) 2010-03-31 2017-03-13 길리애드 파마셋 엘엘씨 뉴클레오사이드 포스포르아미데이트
CA2815154A1 (en) 2010-08-06 2012-02-09 U3 Pharma Gmbh Use of her3 binding agents in prostate treatment
DE102011113652A1 (de) 2011-09-19 2013-03-21 Heraeus Precious Metals Gmbh & Co. Kg Kristallisierung von Idarubicinhydrochlorid
EP4176871A1 (en) 2011-10-03 2023-05-10 Canqura Oncology Ab Nanoparticles, process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
WO2014163558A1 (en) 2013-04-01 2014-10-09 Moreinx Ab Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds
EP3669890A1 (en) 2018-12-18 2020-06-24 Croda International PLC Filamentous nanoparticles having vaccine adjuvant effect

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3427300A (en) * 1965-11-12 1969-02-11 Merck & Co Inc Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3803124A (en) * 1968-04-12 1974-04-09 Farmaceutici It Soc Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) * 1968-05-14 1972-08-22 Farmaceutici Italia Dihydrodaunomycin antibiotic and derivatives thereof

Also Published As

Publication number Publication date
FR2274629A1 (fr) 1976-01-09
DK147304B (da) 1984-06-12
DE2525633C3 (nl) 1979-10-18
CH611317A5 (nl) 1979-05-31
JPS5840557B2 (ja) 1983-09-06
BE830090A (fr) 1975-12-11
GB1467383A (en) 1977-03-16
NL7506745A (nl) 1975-12-16
ES438431A1 (es) 1977-02-01
NL173272B (nl) 1983-08-01
SE7506589L (sv) 1975-12-15
JPS518260A (nl) 1976-01-23
SU645588A3 (ru) 1979-01-30
MY103666A (en) 1993-08-28
US4046878A (en) 1977-09-06
DE2525633A1 (de) 1976-01-02
DE19375027I2 (de) 2002-06-13
DK256875A (da) 1975-12-13
AT337363B (de) 1977-06-27
AU8197975A (en) 1976-12-16
ZA753722B (en) 1976-09-29
DE2525633B2 (nl) 1979-03-01
HK982A (en) 1982-01-22
DK147304C (da) 1984-12-17
ATA437375A (de) 1976-10-15
BG61059B2 (bg) 1996-09-30
NL173272C (nl) 1984-01-02
FR2274629B1 (nl) 1980-01-11

Similar Documents

Publication Publication Date Title
SE423633B (sv) Forfarande for framstellning av 4-demetoxi-daunomycin
SE427752B (sv) Forfarande for framstellning n-fosfonometylglycin
SE428562B (sv) Forfarande for framstellning av purinderivat
NO147037C (no) Fremgangsmaate ved fremstilling av cellulosemasse
SE421919B (sv) Forfarande for framstellning av 2-tetrahydrofurfuryl-6,7-bensomorfaner
SE7508406L (sv) Forfarande for framstellning av polyfenylenoxid.
IT1042173B (it) Procedimento per preparare butandioli
SE431211B (sv) Forfarande for framstellning av n-acylamino-alfa-arylacetamido-cefalosporiner
SE412066B (sv) Forfarande for framstellning av famakologiskt verksamma tienodiazinderivat
SE421612B (sv) Forfarande for framstellning av alfa-6-deoxi-5-hydroxitetracyklin
SE7508074L (sv) Forfarande for framstellning av stilbenderivat.
SE421921B (sv) Analogiforfarande for framstellning av pyridobensodiazepinoner
SE418292B (sv) Forfarande for framstellning av 5-aryl-2-furamidiner
SE422052B (sv) Forfarande for framstellning av vissa angivna 1-fenoxi-2-hydroxi-3-aminofenyl-propylderivat
SE400960B (sv) Forfarande for framstellning av alhŸ3 (poŸ4)Ÿ2 3hŸ2o
SE425739B (sv) Forfarande for framstellning av vissa angivna tetrazolyl-bensopyranopyridinderivat
SE414926B (sv) Forfarande for framstellning av 1-alkyl-2-(fenoximetyl)-5-nitroimidazoler
SE422210B (sv) Analogiforfarande for framstellning av substituerade indoler
NO147671C (no) Fremgangsmaate ved fremstilling av 2-deutero-3-fluor-dl-alanin
SE415658B (sv) Analogiforfarande for framstellning av linnolinderivat
SE404364B (sv) Forfarande for framstellning av vissa angivna 5-sulfonylfenyl-tetrazolderivat
SE425784B (sv) Analogiforfarande for framstellning av eburnameninderivat
SE421310B (sv) Forfarande for framstellning av substituerade bensoylpyridiner
IT1040067B (it) Procedimento per preparare clorosilani
IT7947504A0 (it) Procedimento per preparare mono-o-b-idrossietil-7-rutoside

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7506589-6

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7506589-6

Format of ref document f/p: F