SE416645B - Forfarande for framstellning av 6-deoxitetracykliner genom katalytisk hydrogenering av eventuellt 11a-halogenerade 6-demetyl-6-deoxi-6-metylentetracykliner - Google Patents

Forfarande for framstellning av 6-deoxitetracykliner genom katalytisk hydrogenering av eventuellt 11a-halogenerade 6-demetyl-6-deoxi-6-metylentetracykliner

Info

Publication number
SE416645B
SE416645B SE7403949A SE7403949A SE416645B SE 416645 B SE416645 B SE 416645B SE 7403949 A SE7403949 A SE 7403949A SE 7403949 A SE7403949 A SE 7403949A SE 416645 B SE416645 B SE 416645B
Authority
SE
Sweden
Prior art keywords
metylentetracyclines
halogenered
deoxi
deoxytetracyclines
demethyl
Prior art date
Application number
SE7403949A
Other languages
English (en)
Swedish (sv)
Inventor
Jr T A Morris
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26997777&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE416645(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of SE416645B publication Critical patent/SE416645B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
    • C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/40—Ortho- or ortho- and peri-condensed systems containing four condensed rings
    • C07C2603/42—Ortho- or ortho- and peri-condensed systems containing four condensed rings containing only six-membered rings
    • C07C2603/44—Naphthacenes; Hydrogenated naphthacenes
    • C07C2603/46—1,4,4a,5,5a,6,11,12a- Octahydronaphthacenes, e.g. tetracyclines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7403949A 1973-04-20 1974-03-22 Forfarande for framstellning av 6-deoxitetracykliner genom katalytisk hydrogenering av eventuellt 11a-halogenerade 6-demetyl-6-deoxi-6-metylentetracykliner SE416645B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35308473A 1973-04-20 1973-04-20
US05/421,206 US3954862A (en) 1973-04-20 1973-12-03 Process for producing α-6-deoxytetracyclines

Publications (1)

Publication Number Publication Date
SE416645B true SE416645B (sv) 1981-01-26

Family

ID=26997777

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7403949A SE416645B (sv) 1973-04-20 1974-03-22 Forfarande for framstellning av 6-deoxitetracykliner genom katalytisk hydrogenering av eventuellt 11a-halogenerade 6-demetyl-6-deoxi-6-metylentetracykliner

Country Status (30)

Country Link
US (1) US3954862A (es)
JP (1) JPS5710863B2 (es)
AR (1) AR200521A1 (es)
AT (1) AT333954B (es)
AU (1) AU461511B2 (es)
BG (1) BG25070A3 (es)
CA (1) CA1011736A (es)
CH (1) CH589044A5 (es)
CS (2) CS235092B2 (es)
DD (1) DD114404A5 (es)
DE (1) DE2418499C2 (es)
DK (1) DK155662C (es)
EG (1) EG11172A (es)
ES (1) ES425221A1 (es)
FI (1) FI60196C (es)
FR (1) FR2226389B1 (es)
GB (1) GB1458744A (es)
HK (1) HK28279A (es)
IE (1) IE40048B1 (es)
IL (1) IL44492A (es)
IN (1) IN138740B (es)
KE (1) KE2937A (es)
LU (1) LU69856A1 (es)
MY (1) MY7900242A (es)
NL (1) NL157893B (es)
NO (1) NO146596C (es)
PH (1) PH10555A (es)
RO (2) RO78908A (es)
SE (1) SE416645B (es)
YU (1) YU39303B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500458A (en) * 1982-01-19 1985-02-19 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
US4743699A (en) * 1982-01-19 1988-05-10 Plurichemie Anstalt Homogeneous catalytic system and a process for the preparation of same
USRE32535E (en) * 1982-01-19 1987-10-27 Plurichemie Anstalt Process for the preparation of α-6-deoxytetracyclines
DK386784A (da) * 1983-08-17 1985-02-18 Hovione Int Ltd Fremgangsmaade til fremstilling af alfa-6-desoxy-tetracykliner
JPS6343554U (es) * 1986-09-05 1988-03-23
US4973719A (en) * 1988-10-28 1990-11-27 Ranbaxy Laboratories Limited Process for the production of alpha-6-deoxytetracyclines
US4987242A (en) * 1988-10-28 1991-01-22 Jagmohan Khanna Hydrogenation catalyst useful in the production of alpha-6-deoxytetracyclines
EP0452412A4 (en) * 1989-01-04 1992-06-03 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
US5049683A (en) * 1989-01-04 1991-09-17 Houba, Inc. Process for the production of alpha-6-deoxytetracyclines
DE391005T1 (de) * 1989-04-03 1991-04-11 Ranbaxy Laboratories, Ltd., New Delhi Verfahren zur herstellung von alpha-6-deoxytetracyclinen.
DE102007003434A1 (de) 2007-01-23 2008-07-24 Jäger, Anton Reinigungsvorrichtung
CN105152961B (zh) * 2015-08-31 2017-07-11 河南师范大学 一种强力霉素中间体6‑次甲基土霉素的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1430859A (es) * 1960-05-23 1966-05-25
GB1418137A (en) * 1972-02-24 1975-12-17 Ankerfarm Spa Process for the preparation of alpha-6-deoxytetracyclines

Also Published As

Publication number Publication date
NO741223L (no) 1974-10-22
RO78908A (ro) 1982-08-17
AU6714374A (en) 1975-05-29
EG11172A (en) 1977-01-31
NL157893B (nl) 1978-09-15
NO146596C (no) 1982-11-03
MY7900242A (en) 1979-12-31
PH10555A (en) 1977-06-08
JPS5710863B2 (es) 1982-03-01
YU39303B (en) 1984-10-31
JPS49135961A (es) 1974-12-27
FI60196C (fi) 1981-12-10
BG25070A3 (en) 1978-07-12
NO146596B (no) 1982-07-26
AR200521A1 (es) 1974-11-15
YU85974A (en) 1982-05-31
NL7404666A (es) 1974-10-22
AU461511B2 (en) 1975-05-29
ATA292274A (de) 1976-04-15
CH589044A5 (es) 1977-06-30
AT333954B (de) 1976-12-27
FR2226389B1 (es) 1976-12-17
US3954862A (en) 1976-05-04
DK155662B (da) 1989-05-01
DE2418499C2 (de) 1982-12-23
KE2937A (en) 1979-03-30
FI60196B (fi) 1981-08-31
DD114404A5 (es) 1975-08-05
FR2226389A1 (es) 1974-11-15
DK155662C (da) 1989-10-09
CS235053B2 (en) 1985-04-16
IL44492A (en) 1977-01-31
CS235092B2 (en) 1985-04-16
IE40048B1 (en) 1979-02-28
IL44492A0 (en) 1974-06-30
DE2418499A1 (de) 1974-11-07
IN138740B (es) 1976-03-27
ES425221A1 (es) 1976-05-16
RO80170A (ro) 1982-10-26
CA1011736A (en) 1977-06-07
GB1458744A (en) 1976-12-15
HK28279A (en) 1979-05-11
LU69856A1 (es) 1974-11-21
IE40048L (en) 1975-06-03

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