SE411754B - PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (2-PYRROLIDINYLALKYL) -BENZAMIDE - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (2-PYRROLIDINYLALKYL) -BENZAMIDE

Info

Publication number
SE411754B
SE411754B SE7502342A SE7502342A SE411754B SE 411754 B SE411754 B SE 411754B SE 7502342 A SE7502342 A SE 7502342A SE 7502342 A SE7502342 A SE 7502342A SE 411754 B SE411754 B SE 411754B
Authority
SE
Sweden
Prior art keywords
pyrrolidinylalkyl
benzamide
procedure
preparation
therapeutically active
Prior art date
Application number
SE7502342A
Other languages
Swedish (sv)
Other versions
SE7502342L (en
Inventor
G Bulteau
J Acher
J-C Monier
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7407535A external-priority patent/FR2262966A1/en
Priority claimed from FR7503800A external-priority patent/FR2299863B1/en
Application filed by Ile De France filed Critical Ile De France
Publication of SE7502342L publication Critical patent/SE7502342L/xx
Publication of SE411754B publication Critical patent/SE411754B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7502342A 1974-03-05 1975-03-03 PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (2-PYRROLIDINYLALKYL) -BENZAMIDE SE411754B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7407535A FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity
FR7503800A FR2299863B1 (en) 1975-02-07 1975-02-07 Novel substituted N- (Z-pyrrolidiny alkyl) benzamides, their derivatives and process for their preparation

Publications (2)

Publication Number Publication Date
SE7502342L SE7502342L (en) 1975-09-06
SE411754B true SE411754B (en) 1980-02-04

Family

ID=26218210

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7502342A SE411754B (en) 1974-03-05 1975-03-03 PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (2-PYRROLIDINYLALKYL) -BENZAMIDE

Country Status (27)

Country Link
JP (1) JPS6015616B2 (en)
AR (1) AR206621A1 (en)
AT (1) AT358570B (en)
BG (1) BG24666A3 (en)
CA (1) CA1047504A (en)
CH (1) CH605794A5 (en)
CS (1) CS189692B2 (en)
DD (1) DD119420A5 (en)
DE (1) DE2507989A1 (en)
DK (1) DK145377C (en)
EG (1) EG12577A (en)
ES (1) ES435274A1 (en)
FI (1) FI750620A (en)
GB (1) GB1466822A (en)
HK (1) HK14078A (en)
HU (1) HU170637B (en)
IE (1) IE40818B1 (en)
IL (1) IL46696A (en)
LU (1) LU71949A1 (en)
NL (1) NL7502608A (en)
NO (1) NO750713L (en)
OA (1) OA04966A (en)
PH (1) PH14197A (en)
PL (1) PL97091B1 (en)
RO (2) RO70647A (en)
SE (1) SE411754B (en)
SU (1) SU609464A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186175A (en) * 1977-01-27 1980-03-05 Shionogi & Co Meta-sulphonamidobenzamide derivatives
SE8503054D0 (en) * 1985-06-19 1985-06-19 Astra Laekemedel Ab CATECHOLCARBOXAMIDES
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
EP0314483A1 (en) * 1987-10-29 1989-05-03 Erbamont, Inc. Preparation of benzamides
FR2699533A1 (en) * 1992-12-21 1994-06-24 Mouhtaram Mohamed N-2-piperazinyl 4-amino:benzamide derivs. having antiemetic and antipsychotic activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078497A (en) * 1960-12-29 1963-02-26 Leeds And Mieallef Dispensing containers

Also Published As

Publication number Publication date
HU170637B (en) 1977-07-28
RO70647A (en) 1980-04-15
IL46696A0 (en) 1975-04-25
ATA160775A (en) 1980-02-15
DK145377C (en) 1983-04-11
DE2507989A1 (en) 1975-09-11
CA1047504A (en) 1979-01-30
GB1466822A (en) 1977-03-09
DD119420A5 (en) 1976-04-20
CH605794A5 (en) 1978-10-13
PH14197A (en) 1981-03-26
DK145377B (en) 1982-11-08
OA04966A (en) 1980-10-31
IE40818B1 (en) 1979-08-29
IL46696A (en) 1978-07-31
FI750620A (en) 1975-09-06
EG12577A (en) 1979-09-30
AR206621A1 (en) 1976-08-06
JPS50123668A (en) 1975-09-29
CS189692B2 (en) 1979-04-30
PL97091B1 (en) 1978-02-28
SU609464A1 (en) 1978-05-30
IE40818L (en) 1975-09-05
DK86975A (en) 1975-11-03
BG24666A3 (en) 1978-04-12
NL7502608A (en) 1975-09-09
JPS6015616B2 (en) 1985-04-20
RO72844A (en) 1981-09-24
ES435274A1 (en) 1976-12-16
NO750713L (en) 1975-09-08
SU609464A3 (en) 1978-05-30
AU7874075A (en) 1976-09-09
SE7502342L (en) 1975-09-06
AT358570B (en) 1980-09-25
LU71949A1 (en) 1976-02-04
HK14078A (en) 1978-03-23

Similar Documents

Publication Publication Date Title
SE430329B (en) PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY EFFECTIVE ASSOCIATIONS
SE411753B (en) PROCEDURE FOR PREPARING THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (1-BENZYLPYRROLIDINYL-2-ALKYL) -BENZAMIDE
NO149106C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BENZCYCLOAMIDES
NO147450C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE CHINAZOLONE DERIVATIVES
SE7612202L (en) NEW AMINOBENZOIC ACID AMIDES AND PROCEDURES FOR THE PREPARATION OF THESE.
SE7513571L (en) PROCEDURE FOR THE PREPARATION OF NEW SUBSTITUTED PYRIDINES
NO141013C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE BIFENYLYL DERIVATIVES
NO151040C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 5-HALOGENPYRIMID-2-ONES
NO142033C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE ISOPROPYLAMINO-3-PHENOXYPROPANOLS
NO142838C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ISOQINOLINE DERIVATIVES
SE7510988L (en) NEW PHARMACEUTICAL ACTIVE ASSOCIATIONS
NO141894C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE PYRIDOBENZODIAZEPINONES
NO146199C (en) PROCEDURE FOR THE PREPARATION OF ALFA-6-DEOXY-5-HYDROXYTETRACYCLINE HYDROCHLORIDE
SE405598B (en) PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY EFFICIENT DERIVATIVES OF 4- (3-AMINO-2-HYDROXI-PROPOXI) -INDOL
NO810816L (en) STARTING MATERIAL FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE AMINO ACID DERIVATIVES
NO144108C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE N- (1-BENZYLPIPERID-4-YL) -BENZAMIDES
NO140012C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF NEW THERAPEUTICALLY ACTIVE DERIVATIVES OF NAFTYRIDINE
SE411754B (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NEW DERIVATIVES OF N- (2-PYRROLIDINYLALKYL) -BENZAMIDE
NO137894C (en) ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE AMIDOXIMES
SE428688B (en) PROCEDURE FOR THE PREPARATION OF NEW ANTIDIABETIC ACTIVE ISOOXAZOLD DERIVATIVES
NO143499C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE INHANDER DERIVATIVES
NO145950C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE HOMOPHALIMIDES
NO145238C (en) ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIHYDROCARBOSTYRIL DERIVATIVES
NO143317C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE TIAZINE Dioxides
SE402106B (en) PROCEDURE FOR THE PREPARATION OF NEW N- (Ÿ-AMINO) -ALKYLANILIN DERIVATIVES

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7502342-4

Effective date: 19931008

Format of ref document f/p: F