DK145377C - METHOD OF ANALOGUE FOR THE PREPARATION OF N- (2'-PYRROLIDINYLMETHYL) BENZAMIDES OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALT OR OPTICALLY ACTIVE ISOMERS THEREOF - Google Patents

METHOD OF ANALOGUE FOR THE PREPARATION OF N- (2'-PYRROLIDINYLMETHYL) BENZAMIDES OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALT OR OPTICALLY ACTIVE ISOMERS THEREOF

Info

Publication number
DK145377C
DK145377C DK86975A DK86975A DK145377C DK 145377 C DK145377 C DK 145377C DK 86975 A DK86975 A DK 86975A DK 86975 A DK86975 A DK 86975A DK 145377 C DK145377 C DK 145377C
Authority
DK
Denmark
Prior art keywords
pyrrolidinylmethyl
benzamides
analogue
preparation
quaternary ammonium
Prior art date
Application number
DK86975A
Other languages
Danish (da)
Other versions
DK145377B (en
DK86975A (en
Inventor
G Bulteau
J Acher
J-C Monier
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7407535A external-priority patent/FR2262966A1/en
Priority claimed from FR7503800A external-priority patent/FR2299863B1/en
Application filed by Ile De France filed Critical Ile De France
Publication of DK86975A publication Critical patent/DK86975A/da
Publication of DK145377B publication Critical patent/DK145377B/en
Application granted granted Critical
Publication of DK145377C publication Critical patent/DK145377C/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/282-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK86975A 1974-03-05 1975-03-04 METHOD OF ANALOGUE FOR THE PREPARATION OF N- (2'-PYRROLIDINYLMETHYL) BENZAMIDES OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALT OR OPTICALLY ACTIVE ISOMERS THEREOF DK145377C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7407535 1974-03-05
FR7407535A FR2262966A1 (en) 1974-03-05 1974-03-05 N-(2-azacycloalkyl-alkyl)-benzamide derivs. - with antiemetic, antiulcer and CNS activity
FR7503800A FR2299863B1 (en) 1975-02-07 1975-02-07 Novel substituted N- (Z-pyrrolidiny alkyl) benzamides, their derivatives and process for their preparation
FR7503800 1975-02-07

Publications (3)

Publication Number Publication Date
DK86975A DK86975A (en) 1975-11-03
DK145377B DK145377B (en) 1982-11-08
DK145377C true DK145377C (en) 1983-04-11

Family

ID=26218210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK86975A DK145377C (en) 1974-03-05 1975-03-04 METHOD OF ANALOGUE FOR THE PREPARATION OF N- (2'-PYRROLIDINYLMETHYL) BENZAMIDES OR ACID ADDITION SALTS OR QUATERNARY AMMONIUM SALT OR OPTICALLY ACTIVE ISOMERS THEREOF

Country Status (27)

Country Link
JP (1) JPS6015616B2 (en)
AR (1) AR206621A1 (en)
AT (1) AT358570B (en)
BG (1) BG24666A3 (en)
CA (1) CA1047504A (en)
CH (1) CH605794A5 (en)
CS (1) CS189692B2 (en)
DD (1) DD119420A5 (en)
DE (1) DE2507989A1 (en)
DK (1) DK145377C (en)
EG (1) EG12577A (en)
ES (1) ES435274A1 (en)
FI (1) FI750620A (en)
GB (1) GB1466822A (en)
HK (1) HK14078A (en)
HU (1) HU170637B (en)
IE (1) IE40818B1 (en)
IL (1) IL46696A (en)
LU (1) LU71949A1 (en)
NL (1) NL7502608A (en)
NO (1) NO750713L (en)
OA (1) OA04966A (en)
PH (1) PH14197A (en)
PL (1) PL97091B1 (en)
RO (2) RO72844A (en)
SE (1) SE411754B (en)
SU (1) SU609464A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ186175A (en) * 1977-01-27 1980-03-05 Shionogi & Co Meta-sulphonamidobenzamide derivatives
SE8503054D0 (en) * 1985-06-19 1985-06-19 Astra Laekemedel Ab CATECHOLCARBOXAMIDES
US4772459A (en) * 1986-09-09 1988-09-20 Erbamont, Inc. Method for controlling emesis caused by chemotherapeutic agents and antiemetic agents useful therein
EP0314483A1 (en) * 1987-10-29 1989-05-03 Erbamont, Inc. Preparation of benzamides
FR2699533A1 (en) * 1992-12-21 1994-06-24 Mouhtaram Mohamed N-2-piperazinyl 4-amino:benzamide derivs. having antiemetic and antipsychotic activity

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078497A (en) * 1960-12-29 1963-02-26 Leeds And Mieallef Dispensing containers

Also Published As

Publication number Publication date
SU609464A3 (en) 1978-05-30
JPS6015616B2 (en) 1985-04-20
OA04966A (en) 1980-10-31
AT358570B (en) 1980-09-25
CA1047504A (en) 1979-01-30
ATA160775A (en) 1980-02-15
DK145377B (en) 1982-11-08
SE7502342L (en) 1975-09-08
ES435274A1 (en) 1976-12-16
CS189692B2 (en) 1979-04-30
FI750620A (en) 1975-09-06
JPS50123668A (en) 1975-09-29
AR206621A1 (en) 1976-08-06
NO750713L (en) 1975-09-08
IE40818B1 (en) 1979-08-29
IE40818L (en) 1975-09-05
HU170637B (en) 1977-07-28
DE2507989A1 (en) 1975-09-11
RO72844A (en) 1981-09-24
BG24666A3 (en) 1978-04-12
DD119420A5 (en) 1976-04-20
EG12577A (en) 1979-09-30
PH14197A (en) 1981-03-26
DK86975A (en) 1975-11-03
RO70647A (en) 1980-04-15
NL7502608A (en) 1975-09-09
AU7874075A (en) 1976-09-09
PL97091B1 (en) 1978-02-28
SU609464A1 (en) 1978-05-30
LU71949A1 (en) 1976-02-04
IL46696A (en) 1978-07-31
HK14078A (en) 1978-03-23
CH605794A5 (en) 1978-10-13
SE411754B (en) 1980-02-04
IL46696A0 (en) 1975-04-25
GB1466822A (en) 1977-03-09

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