SE405121B - Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter - Google Patents
Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalterInfo
- Publication number
- SE405121B SE405121B SE7308564A SE7308564A SE405121B SE 405121 B SE405121 B SE 405121B SE 7308564 A SE7308564 A SE 7308564A SE 7308564 A SE7308564 A SE 7308564A SE 405121 B SE405121 B SE 405121B
- Authority
- SE
- Sweden
- Prior art keywords
- benzomorphanes
- 9beta
- dialkyl
- heteroaryl
- methyl
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2229695A DE2229695A1 (de) | 1972-06-19 | 1972-06-19 | 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE405121B true SE405121B (sv) | 1978-11-20 |
Family
ID=5848060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7308564A SE405121B (sv) | 1972-06-19 | 1973-06-18 | Forfarande for framstellning av 2-(heteroaryl-metyl)-5-9beta-dialkyl-6,7-bensomorfaner eller deras syraadditionssalter |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3931194A (enExample) |
| JP (1) | JPS5711908B2 (enExample) |
| AT (6) | AT329200B (enExample) |
| BE (1) | BE801079A (enExample) |
| CH (9) | CH589649A5 (enExample) |
| DE (1) | DE2229695A1 (enExample) |
| DK (1) | DK136904C (enExample) |
| ES (8) | ES416037A1 (enExample) |
| FR (1) | FR2189056B1 (enExample) |
| GB (1) | GB1433817A (enExample) |
| NL (1) | NL7308483A (enExample) |
| NO (1) | NO137694C (enExample) |
| SE (1) | SE405121B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2437610A1 (de) * | 1974-08-05 | 1976-02-26 | Boehringer Sohn Ingelheim | Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung |
| GB1575009A (en) * | 1976-06-21 | 1980-09-17 | Acf Chemiefarma Nv | 6,7-benzomorphan derivatives |
| JPS63177704A (ja) * | 1987-01-16 | 1988-07-21 | 松山株式会社 | 農作業機連結装置 |
| JP5451611B2 (ja) | 2007-07-26 | 2014-03-26 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター |
| US8859580B2 (en) | 2007-11-16 | 2014-10-14 | Boehringer Ingelheim International Gmbh | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| CA2708303A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| WO2009094169A1 (en) | 2008-01-24 | 2009-07-30 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CA2711757C (en) * | 2008-02-12 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| US8598160B2 (en) | 2008-02-15 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| TW201004945A (en) | 2008-05-01 | 2010-02-01 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| KR20110002492A (ko) | 2008-05-01 | 2011-01-07 | 비타이 파마슈티컬즈, 인코포레이티드 | 11베타-하이드록시스테로이드 탈수소효소 1의 고리형 억제제 |
| EP2291370B1 (en) | 2008-05-01 | 2013-11-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| WO2010011314A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
| US8846668B2 (en) | 2008-07-25 | 2014-09-30 | Vitae Pharmaceuticals, Inc. | Inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| UA109255C2 (ru) | 2009-04-30 | 2015-08-10 | Берінгер Інгельхайм Інтернешнл Гмбх | Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| AR078887A1 (es) | 2009-11-06 | 2011-12-07 | Boehringer Ingelheim Int | Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen. |
| EP2582698B1 (en) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use |
| TWI537258B (zh) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物 |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE582575A (enExample) * | 1958-09-22 | |||
| FR1281227A (fr) * | 1958-09-22 | 1962-01-12 | Smith Kline French Lab | Perfectionnements apportés aux procédés pour la préparation de dérivés d'aralcoylbenzomorphane |
| CS166803B2 (enExample) * | 1971-02-08 | 1976-03-29 | Boehringer Sohn Ingelheim | |
| SE392895B (sv) * | 1971-08-24 | 1977-04-25 | Sumitomo Chemical Co | Forfarande for framstellning av bensomorfanderivat och deras salter |
-
1972
- 1972-06-19 DE DE2229695A patent/DE2229695A1/de not_active Withdrawn
-
1973
- 1973-06-05 US US05/367,114 patent/US3931194A/en not_active Expired - Lifetime
- 1973-06-06 AT AT489974*7A patent/AT329200B/de not_active IP Right Cessation
- 1973-06-06 AT AT489774*7A patent/AT328628B/de not_active IP Right Cessation
- 1973-06-06 AT AT489874*7A patent/AT329199B/de not_active IP Right Cessation
- 1973-06-06 AT AT489474*7A patent/AT328627B/de not_active IP Right Cessation
- 1973-06-06 AT AT494373A patent/AT325218B/de not_active IP Right Cessation
- 1973-06-06 AT AT490074*7A patent/AT328629B/de not_active IP Right Cessation
- 1973-06-14 CH CH1041476A patent/CH589649A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041176A patent/CH582697A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041376A patent/CH582698A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041576A patent/CH583231A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041276A patent/CH589648A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH864373A patent/CH583227A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040976A patent/CH583229A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1040876A patent/CH583228A5/xx not_active IP Right Cessation
- 1973-06-14 CH CH1041076A patent/CH583230A5/xx not_active IP Right Cessation
- 1973-06-18 NO NO2518/73A patent/NO137694C/no unknown
- 1973-06-18 JP JP6863473A patent/JPS5711908B2/ja not_active Expired
- 1973-06-18 GB GB2886973A patent/GB1433817A/en not_active Expired
- 1973-06-18 ES ES416037A patent/ES416037A1/es not_active Expired
- 1973-06-18 BE BE132406A patent/BE801079A/xx unknown
- 1973-06-18 SE SE7308564A patent/SE405121B/xx unknown
- 1973-06-18 DK DK336173A patent/DK136904C/da active
- 1973-06-19 NL NL7308483A patent/NL7308483A/xx not_active Application Discontinuation
- 1973-06-19 FR FR7322249A patent/FR2189056B1/fr not_active Expired
-
1974
- 1974-10-30 ES ES431515A patent/ES431515A1/es not_active Expired
- 1974-10-30 ES ES431511A patent/ES431511A1/es not_active Expired
- 1974-10-30 ES ES431513A patent/ES431513A1/es not_active Expired
- 1974-10-30 ES ES431514A patent/ES431514A1/es not_active Expired
- 1974-10-30 ES ES0431516A patent/ES431516A1/es not_active Expired
- 1974-10-30 ES ES431510A patent/ES431510A1/es not_active Expired
- 1974-10-30 ES ES431512A patent/ES431512A1/es not_active Expired
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