SE399702B - Analogiforfarande for framstellning av 2-amino-2'6'-propionoxylidid, som uppvisar en kraftig antiarrytmisk effekt - Google Patents

Analogiforfarande for framstellning av 2-amino-2'6'-propionoxylidid, som uppvisar en kraftig antiarrytmisk effekt

Info

Publication number
SE399702B
SE399702B SE7208768A SE876872A SE399702B SE 399702 B SE399702 B SE 399702B SE 7208768 A SE7208768 A SE 7208768A SE 876872 A SE876872 A SE 876872A SE 399702 B SE399702 B SE 399702B
Authority
SE
Sweden
Prior art keywords
propionoxylidide
amino
production
shows
antiarrhythmic effect
Prior art date
Application number
SE7208768A
Other languages
English (en)
Swedish (sv)
Inventor
R N Boyes
B R Duce
E R Smith
E W Byrnes
Original Assignee
Astra Pharma Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharma Prod filed Critical Astra Pharma Prod
Publication of SE399702B publication Critical patent/SE399702B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7208768A 1971-07-28 1972-07-04 Analogiforfarande for framstellning av 2-amino-2'6'-propionoxylidid, som uppvisar en kraftig antiarrytmisk effekt SE399702B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16703171A 1971-07-28 1971-07-28

Publications (1)

Publication Number Publication Date
SE399702B true SE399702B (sv) 1978-02-27

Family

ID=22605664

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7208768A SE399702B (sv) 1971-07-28 1972-07-04 Analogiforfarande for framstellning av 2-amino-2'6'-propionoxylidid, som uppvisar en kraftig antiarrytmisk effekt

Country Status (23)

Country Link
JP (1) JPS565220B1 (enExample)
AR (1) AR193748A1 (enExample)
AT (1) AT317185B (enExample)
AU (1) AU476000B2 (enExample)
BE (1) BE786875A (enExample)
BR (1) BR7205069D0 (enExample)
CA (1) CA982148A (enExample)
CH (1) CH574397A5 (enExample)
CS (1) CS171171B2 (enExample)
DD (1) DD101389A5 (enExample)
DK (1) DK142843B (enExample)
ES (1) ES404739A1 (enExample)
FI (1) FI55492C (enExample)
FR (1) FR2147277B1 (enExample)
GB (1) GB1374367A (enExample)
HU (1) HU163818B (enExample)
IE (1) IE36607B1 (enExample)
NL (1) NL176254C (enExample)
NO (1) NO137500C (enExample)
PL (1) PL84891B1 (enExample)
SE (1) SE399702B (enExample)
SU (1) SU441704A3 (enExample)
ZA (1) ZA724512B (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57182525U (enExample) * 1981-05-15 1982-11-19
JPH01128053U (enExample) * 1988-02-24 1989-08-31
JP2514855B2 (ja) * 1990-08-08 1996-07-10 キッセイ薬品工業株式会社 光学活性なアラニンアニリド誘導体の酸付加塩
GB2267709A (en) * 1992-06-11 1993-12-15 Merck & Co Inc Novel process for the preparation of alpha-aminoacylanilides
JP6205133B2 (ja) 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
DE102012210082A1 (de) * 2012-06-15 2013-12-19 Hilti Aktiengesellschaft Werkzeugmaschine und Steuerungsverfahren
US11021443B2 (en) 2015-08-03 2021-06-01 President And Fellows Of Harvard College Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10934263B2 (en) 2019-03-11 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113950471B (zh) 2019-03-11 2025-01-14 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
US10842798B1 (en) 2019-11-06 2020-11-24 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
BR112022017801A2 (pt) 2020-03-11 2022-10-25 Nocion Therapeutics Inc Bloqueadores de canais de íons carregados e métodos para uso
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Also Published As

Publication number Publication date
PL84891B1 (en) 1976-04-30
FR2147277B1 (enExample) 1976-04-16
AR193748A1 (es) 1973-05-22
NL176254B (nl) 1984-10-16
CH574397A5 (enExample) 1976-04-15
NL176254C (nl) 1985-03-18
BE786875A (fr) 1973-01-29
AU476000B2 (en) 1976-09-09
ZA724512B (en) 1973-08-29
AU4488672A (en) 1974-01-31
IE36607B1 (en) 1976-12-08
NO137500C (no) 1978-03-08
FI55492C (fi) 1979-08-10
DE2235745B2 (de) 1976-08-19
HU163818B (enExample) 1973-11-28
NL7210418A (enExample) 1973-01-30
GB1374367A (en) 1974-11-20
SU441704A3 (ru) 1974-08-30
DK142843C (enExample) 1981-08-31
FI55492B (fi) 1979-04-30
CS171171B2 (enExample) 1976-10-29
BR7205069D0 (pt) 1973-07-17
NO137500B (no) 1977-11-28
DD101389A5 (enExample) 1973-11-05
CA982148A (en) 1976-01-20
DE2235745A1 (de) 1973-02-22
DK142843B (da) 1981-02-09
IE36607L (en) 1973-01-28
FR2147277A1 (enExample) 1973-03-09
AT317185B (de) 1974-08-12
ES404739A1 (es) 1975-07-16
JPS565220B1 (enExample) 1981-02-04

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