SE397523B - Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan - Google Patents

Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan

Info

Publication number
SE397523B
SE397523B SE7402667A SE7402667A SE397523B SE 397523 B SE397523 B SE 397523B SE 7402667 A SE7402667 A SE 7402667A SE 7402667 A SE7402667 A SE 7402667A SE 397523 B SE397523 B SE 397523B
Authority
SE
Sweden
Prior art keywords
phenylpyrle
inflammatory
derivatives
preparing
procedure
Prior art date
Application number
SE7402667A
Other languages
English (en)
Swedish (sv)
Inventor
R C Allen
V B Anderson
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE397523B publication Critical patent/SE397523B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
SE7402667A 1973-03-01 1974-02-28 Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan SE397523B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US336919A US3878225A (en) 1973-03-01 1973-03-01 Condensed pyrroles bearing an N-phenyl substituent

Publications (1)

Publication Number Publication Date
SE397523B true SE397523B (sv) 1977-11-07

Family

ID=23318274

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7402667A SE397523B (sv) 1973-03-01 1974-02-28 Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan

Country Status (20)

Country Link
US (1) US3878225A (fi)
JP (1) JPS6139304B2 (fi)
AT (1) AT332389B (fi)
BE (1) BE811785A (fi)
CA (1) CA1025455A (fi)
CH (1) CH611605A5 (fi)
CS (1) CS191225B2 (fi)
DE (1) DE2407671C2 (fi)
ES (2) ES423562A1 (fi)
FI (1) FI61183C (fi)
FR (1) FR2219790B1 (fi)
GB (1) GB1457601A (fi)
HU (1) HU170834B (fi)
IE (1) IE38943B1 (fi)
IL (1) IL44279A (fi)
NL (1) NL177828C (fi)
NO (1) NO142346C (fi)
SE (1) SE397523B (fi)
SU (1) SU610488A3 (fi)
ZA (1) ZA741333B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056624A (en) * 1976-05-14 1977-11-01 American Hoechst Corporation Method of treating dermal inflammation
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
US5145965A (en) * 1987-09-24 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated 2,6-methanopyrrolo-3-benzazocines
US4814501A (en) * 1987-12-28 1989-03-21 Merck & Co., Inc. Process for preparing N,N-dimethyl 2-(methylthio) benzamides and analogs
JP2008515805A (ja) * 2004-10-04 2008-05-15 ミリアド ジェネティクス, インコーポレイテッド アルツハイマー病のための化合物
US9216966B2 (en) 2004-10-04 2015-12-22 John Manfredi Compounds for Alzheimer's disease
US7678823B2 (en) * 2004-10-04 2010-03-16 Myriad Pharmaceticals, Inc. Compounds for alzheimer's disease
AU2007234399A1 (en) * 2006-04-04 2007-10-11 Myriad Genetics, Inc. Compounds for diseases and disorders
KR20100046107A (ko) * 2007-07-24 2010-05-06 아스텔라스세이야쿠 가부시키가이샤 벤즈이미다졸 유도체
RU2492164C2 (ru) 2008-04-16 2013-09-10 Каро Био Аб Новые лиганды эстрогеновых рецепторов
GB201113538D0 (en) 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (fi) *
US3687971A (en) * 1970-06-22 1972-08-29 Merck & Co Inc 4-(pyrrolyl)-salicylic acid derivatives
GB1351754A (en) * 1970-07-02 1974-05-01 Allen & Hanburys Ltd Indenopyrrole derivatives

Also Published As

Publication number Publication date
NO740694L (no) 1974-09-03
GB1457601A (en) 1976-12-08
AU6618874A (en) 1975-09-04
FI61183B (fi) 1982-02-26
NO142346C (no) 1980-08-06
JPS49134671A (fi) 1974-12-25
IE38943L (en) 1974-09-01
FI61183C (fi) 1982-06-10
ES423562A1 (es) 1976-06-01
NO142346B (no) 1980-04-28
ATA165474A (de) 1976-01-15
HU170834B (hu) 1977-09-28
CS191225B2 (en) 1979-06-29
CH611605A5 (fi) 1979-06-15
SU610488A3 (ru) 1978-06-05
AT332389B (de) 1976-09-27
ZA741333B (en) 1975-02-26
US3878225A (en) 1975-04-15
NL177828C (nl) 1985-12-02
DE2407671C2 (de) 1983-12-01
DE2407671A1 (de) 1974-09-12
BE811785A (fr) 1974-09-02
IL44279A (en) 1977-10-31
FR2219790B1 (fi) 1978-09-22
NL177828B (nl) 1985-07-01
NL7402465A (fi) 1974-09-03
JPS6139304B2 (fi) 1986-09-03
IE38943B1 (en) 1978-07-05
FR2219790A1 (fi) 1974-09-27
IL44279A0 (en) 1974-05-16
CA1025455A (en) 1978-01-31
ES437259A1 (es) 1977-01-01

Similar Documents

Publication Publication Date Title
SE384856B (sv) Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan
SE7415086L (sv) Sotningsmedelskomposition och forfarande for framstellning derav
SE7610422L (sv) Forfarande for framstellning av pyrimidinderivat
SE415761B (sv) Forfarande for framstellning av hexahydro-dibenso(b,d)pyran-9-on-derivat med terapeutisk verkan
SE7710045L (sv) Peptidderivat
SE406467B (sv) Nytt forfarande for framstellning av bensotiazinforeningar med antiinflammatorisk verkan
SE7605925L (sv) Nya prostanderivat och sett att framstella desamma
SE402283B (sv) Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan
SE7603554L (sv) Nitrofurylpyrazolderivat och sett for deras framstellning
SE413244B (sv) Forfarandefor framstellning av bensopyraner med analgetisk verkan
SE397523B (sv) Forfarande att framstella n-fenylpyrrolderivat med antiinflammatorisk och analgetisk verkan
SE433745B (sv) Forfarande for framstellning av tetrahydroisokinolinderivat
SE407575B (sv) Forfarande for framstellning av 1,3-dioxanderivat med terapentisk verkan
SE421319B (sv) Forfarande for framstellning av etbara polysackarider och polysackaridderivat
SE423390B (sv) Foerfarande foer framstaellning av eburnameninderivat
IT1055549B (it) Derivati azetidinioi e procedimento per la loro preparazione ed impiego
SE440907B (sv) Forfarande for framstellning av imidazolderivat med farmaceutisk verkan
DK378376A (da) Carbonylmethylderivater
SE439159B (sv) Forfarnde for framstellning av nya 5-fluoropyrimidin-4-on-derivat
SE415659B (sv) Forfarande for framstellning av basiskt substituerade xanten- och tioxantenderivat
SE7609956L (sv) Nya antiinflammatoriska l-oxo-isoindotinderivat och forfarande for framstellning derav
SE398230B (sv) Forfarande for framstellning av 1-amino-3-/(pyrrody-1)-fenoxi/-2-propanol och derivat derav med terapeutisk verkan
SE7600704L (sv) Difenyleter-derivat och forfarande for framstellning derav
SE389108B (sv) Forfarande for framstellning av cyklopropylfenylpyrrolidinderivat med farmakologisk verkan
SE7506406L (sv) Nya cyklopentanderivat och forfarande for deras framstellning

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7402667-5

Effective date: 19910117

Format of ref document f/p: F