CA1025455A - N-phenylpyrroies and process for their manufacture - Google Patents

N-phenylpyrroies and process for their manufacture

Info

Publication number
CA1025455A
CA1025455A CA193,763A CA193763A CA1025455A CA 1025455 A CA1025455 A CA 1025455A CA 193763 A CA193763 A CA 193763A CA 1025455 A CA1025455 A CA 1025455A
Authority
CA
Canada
Prior art keywords
phenylpyrroies
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,763A
Other languages
English (en)
French (fr)
Inventor
Richard C. Allen
V. Brian Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of CA1025455A publication Critical patent/CA1025455A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
CA193,763A 1973-03-01 1974-02-28 N-phenylpyrroies and process for their manufacture Expired CA1025455A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US336919A US3878225A (en) 1973-03-01 1973-03-01 Condensed pyrroles bearing an N-phenyl substituent

Publications (1)

Publication Number Publication Date
CA1025455A true CA1025455A (en) 1978-01-31

Family

ID=23318274

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,763A Expired CA1025455A (en) 1973-03-01 1974-02-28 N-phenylpyrroies and process for their manufacture

Country Status (20)

Country Link
US (1) US3878225A (fi)
JP (1) JPS6139304B2 (fi)
AT (1) AT332389B (fi)
BE (1) BE811785A (fi)
CA (1) CA1025455A (fi)
CH (1) CH611605A5 (fi)
CS (1) CS191225B2 (fi)
DE (1) DE2407671C2 (fi)
ES (2) ES423562A1 (fi)
FI (1) FI61183C (fi)
FR (1) FR2219790B1 (fi)
GB (1) GB1457601A (fi)
HU (1) HU170834B (fi)
IE (1) IE38943B1 (fi)
IL (1) IL44279A (fi)
NL (1) NL177828C (fi)
NO (1) NO142346C (fi)
SE (1) SE397523B (fi)
SU (1) SU610488A3 (fi)
ZA (1) ZA741333B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056624A (en) * 1976-05-14 1977-11-01 American Hoechst Corporation Method of treating dermal inflammation
US5145965A (en) * 1987-09-24 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated 2,6-methanopyrrolo-3-benzazocines
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
US4814501A (en) * 1987-12-28 1989-03-21 Merck & Co., Inc. Process for preparing N,N-dimethyl 2-(methylthio) benzamides and analogs
US7678823B2 (en) 2004-10-04 2010-03-16 Myriad Pharmaceticals, Inc. Compounds for alzheimer's disease
EP1809601B1 (en) * 2004-10-04 2014-09-10 Manfredi, John Compounds for alzheimer's disease
US9216966B2 (en) 2004-10-04 2015-12-22 John Manfredi Compounds for Alzheimer's disease
JP2009532501A (ja) * 2006-04-04 2009-09-10 ミリアド ジェネティクス， インコーポレイテッド 疾患および障害のための化合物
US20100190826A1 (en) * 2007-07-24 2010-07-29 Akio Kakefuda Benzimidazole derivative
JP5635493B2 (ja) * 2008-04-16 2014-12-03 カロ バイオ アクチェブラーグ 新規エストロゲン受容体リガンド
GB201113538D0 (en) 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (fi) *
US3687971A (en) * 1970-06-22 1972-08-29 Merck & Co Inc 4-(pyrrolyl)-salicylic acid derivatives
GB1351754A (en) * 1970-07-02 1974-05-01 Allen & Hanburys Ltd Indenopyrrole derivatives

Also Published As

Publication number Publication date
ES423562A1 (es) 1976-06-01
NO142346B (no) 1980-04-28
FI61183C (fi) 1982-06-10
DE2407671A1 (de) 1974-09-12
BE811785A (fr) 1974-09-02
FR2219790B1 (fi) 1978-09-22
HU170834B (hu) 1977-09-28
FR2219790A1 (fi) 1974-09-27
SU610488A3 (ru) 1978-06-05
IE38943B1 (en) 1978-07-05
ATA165474A (de) 1976-01-15
ZA741333B (en) 1975-02-26
IL44279A (en) 1977-10-31
CS191225B2 (en) 1979-06-29
NL7402465A (fi) 1974-09-03
NO740694L (no) 1974-09-03
CH611605A5 (fi) 1979-06-15
NL177828C (nl) 1985-12-02
DE2407671C2 (de) 1983-12-01
IE38943L (en) 1974-09-01
AT332389B (de) 1976-09-27
NO142346C (no) 1980-08-06
IL44279A0 (en) 1974-05-16
JPS6139304B2 (fi) 1986-09-03
US3878225A (en) 1975-04-15
JPS49134671A (fi) 1974-12-25
FI61183B (fi) 1982-02-26
SE397523B (sv) 1977-11-07
AU6618874A (en) 1975-09-04
GB1457601A (en) 1976-12-08
NL177828B (nl) 1985-07-01
ES437259A1 (es) 1977-01-01

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