SE384856B - Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan - Google Patents

Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan

Info

Publication number
SE384856B
SE384856B SE7214215A SE1421572A SE384856B SE 384856 B SE384856 B SE 384856B SE 7214215 A SE7214215 A SE 7214215A SE 1421572 A SE1421572 A SE 1421572A SE 384856 B SE384856 B SE 384856B
Authority
SE
Sweden
Prior art keywords
analgetic
inflammatory
way
antipyretic effects
preparing content
Prior art date
Application number
SE7214215A
Other languages
English (en)
Swedish (sv)
Inventor
G R Birchall
W Hepworth
S C Smith
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of SE384856B publication Critical patent/SE384856B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7214215A 1971-11-03 1972-11-02 Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan SE384856B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1811672A GB1356834A (en) 1971-11-03 1971-11-03 Indole derivatives
GB1811672 1972-04-19
GB3076772 1972-06-30

Publications (1)

Publication Number Publication Date
SE384856B true SE384856B (sv) 1976-05-24

Family

ID=27257588

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7214215A SE384856B (sv) 1971-11-03 1972-11-02 Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan

Country Status (17)

Country Link
US (1) US3884919A (fr)
JP (1) JPS4856667A (fr)
AR (3) AR198064A1 (fr)
BE (1) BE790679A (fr)
CA (1) CA983932A (fr)
CH (1) CH577499A5 (fr)
DD (1) DD105611A5 (fr)
DE (1) DE2253927A1 (fr)
EG (1) EG11358A (fr)
ES (2) ES408226A1 (fr)
FR (1) FR2158464B1 (fr)
GB (1) GB1356834A (fr)
HU (1) HU169711B (fr)
IE (1) IE37998B1 (fr)
IL (1) IL40521A (fr)
NL (1) NL7214807A (fr)
SE (1) SE384856B (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022780A (en) * 1973-03-06 1977-05-10 Imperial Chemical Industries Limited Process for the manufacture of indole derivatives
FR2421900A1 (fr) * 1977-03-17 1979-11-02 Sauba Lab Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
US4316847A (en) * 1979-07-30 1982-02-23 Hoffmann-La Roche Inc. Pyrroles and pyrrolidines
US4459227A (en) * 1981-03-02 1984-07-10 Duke University Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones
CZ288955B6 (cs) * 1994-02-23 2001-10-17 Pfizer Inc. Substituované chinazolinové deriváty, jejich pouľití a farmaceutické prostředky na jejich bázi
US6252084B1 (en) * 1994-03-15 2001-06-26 Eli Lilly And Company 1H-indole-3-acetamide sPLA2 inhibitors
WO1999043654A2 (fr) * 1998-02-25 1999-09-02 Genetics Institute, Inc. Inhibiteurs d'enzymes phospholipases
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
SE0200411D0 (sv) * 2002-02-05 2002-02-05 Astrazeneca Ab Novel use
SE0200356D0 (sv) * 2002-02-05 2002-02-05 Astrazeneca Ab Novel use
SE0201635D0 (sv) * 2002-05-30 2002-05-30 Astrazeneca Ab Novel compounds
TW200307542A (en) 2002-05-30 2003-12-16 Astrazeneca Ab Novel compounds
SE0202241D0 (sv) 2002-07-17 2002-07-17 Astrazeneca Ab Novel Compounds
SE0301009D0 (sv) * 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
SE0301010D0 (sv) 2003-04-07 2003-04-07 Astrazeneca Ab Novel compounds
PT1471057E (pt) 2003-04-25 2006-05-31 Actimis Pharmaceuticals Inc Derivados de acido pirimidinilacetico uteis para o tratamento de doencas mediadas por crth2
AU2004236239A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
SE0301569D0 (sv) 2003-05-27 2003-05-27 Astrazeneca Ab Novel compounds
SE0302232D0 (sv) * 2003-08-18 2003-08-18 Astrazeneca Ab Novel Compounds
SA04250253B1 (ar) 2003-08-21 2009-11-10 استرازينيكا ايه بي احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن
GB0324763D0 (en) 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
SE0303180D0 (sv) 2003-11-26 2003-11-26 Astrazeneca Ab Novel compounds
ATE433452T1 (de) 2004-01-31 2009-06-15 Actimis Pharmaceuticals Inc Imidazoä1,2-cüpyrimidinylessigsäurederivate
GB0415320D0 (en) 2004-07-08 2004-08-11 Astrazeneca Ab Novel compounds
GB0418830D0 (en) 2004-08-24 2004-09-22 Astrazeneca Ab Novel compounds
JP5208510B2 (ja) 2004-11-23 2013-06-12 アストラゼネカ・アクチエボラーグ 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体
GB0500604D0 (en) 2005-01-13 2005-02-16 Astrazeneca Ab Novel process
TW200745003A (en) 2005-10-06 2007-12-16 Astrazeneca Ab Novel compounds
US8148572B2 (en) 2005-10-06 2012-04-03 Astrazeneca Ab Compounds
EP2125722A2 (fr) 2006-05-26 2009-12-02 AstraZeneca AB Indoles substitues par biaryl ou aryl-heteroaryl
JP5270542B2 (ja) 2006-07-22 2013-08-21 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
UA100983C2 (ru) 2007-07-05 2013-02-25 Астразенека Аб Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты
JP5524847B2 (ja) 2007-09-25 2014-06-18 アクチミス ファーマシューティカルズ インコーポレーテッド Ｃｒｔｈ２アンタゴニストとしてのアルキルチオピリミジン
US8314116B2 (en) 2007-09-25 2012-11-20 Actimis Pharmaceuticals, Inc. 2-S-benzyl substituted pyrimidines as CRTH2 antagonists
ES2442717T3 (es) 2008-01-18 2014-02-13 Atopix Therapeutics Limited Compuestos que tienen actividad antagonista de CRTH2
US7750027B2 (en) 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
JP2011509990A (ja) 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
WO2009093029A1 (fr) 2008-01-22 2009-07-30 Oxagen Limited Composés présentant une activité antagoniste de crth2
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407807D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
JP2022512588A (ja) * 2018-10-05 2022-02-07 バーテックス ファーマシューティカルズ インコーポレイテッド アルファ１アンチトリプシンのモジュレーター

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL125443C (fr) * 1963-06-06
US3679692A (en) * 1969-10-01 1972-07-25 Mead Johnson & Co Iminomethylindolines

Also Published As

Publication number Publication date
HU169711B (fr) 1977-02-28
IL40521A (en) 1975-06-25
IL40521A0 (en) 1972-12-29
CH577499A5 (fr) 1976-07-15
DD105611A5 (fr) 1974-05-05
FR2158464A1 (fr) 1973-06-15
GB1356834A (en) 1974-06-19
JPS4856667A (fr) 1973-08-09
EG11358A (en) 1977-02-28
CA983932A (en) 1976-02-17
AR198064A1 (es) 1974-05-31
NL7214807A (fr) 1973-05-07
AR203626A1 (es) 1975-09-30
IE37998L (en) 1973-05-03
US3884919A (en) 1975-05-20
BE790679A (fr) 1973-04-27
IE37998B1 (en) 1977-12-07
ES437311A1 (es) 1977-04-01
DE2253927A1 (de) 1973-05-10
AR203627A1 (es) 1975-09-30
FR2158464B1 (fr) 1976-07-02
ES408226A1 (es) 1976-02-01

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