FR2158464A1 - - Google Patents
Info
- Publication number
- FR2158464A1 FR2158464A1 FR7238836A FR7238836A FR2158464A1 FR 2158464 A1 FR2158464 A1 FR 2158464A1 FR 7238836 A FR7238836 A FR 7238836A FR 7238836 A FR7238836 A FR 7238836A FR 2158464 A1 FR2158464 A1 FR 2158464A1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1811672A GB1356834A (en) | 1971-11-03 | 1971-11-03 | Indole derivatives |
GB1811672 | 1972-04-19 | ||
GB3076772 | 1972-06-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2158464A1 true FR2158464A1 (fr) | 1973-06-15 |
FR2158464B1 FR2158464B1 (fr) | 1976-07-02 |
Family
ID=27257588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7238836A Expired FR2158464B1 (fr) | 1971-11-03 | 1972-11-02 |
Country Status (17)
Country | Link |
---|---|
US (1) | US3884919A (fr) |
JP (1) | JPS4856667A (fr) |
AR (3) | AR198064A1 (fr) |
BE (1) | BE790679A (fr) |
CA (1) | CA983932A (fr) |
CH (1) | CH577499A5 (fr) |
DD (1) | DD105611A5 (fr) |
DE (1) | DE2253927A1 (fr) |
EG (1) | EG11358A (fr) |
ES (2) | ES408226A1 (fr) |
FR (1) | FR2158464B1 (fr) |
GB (1) | GB1356834A (fr) |
HU (1) | HU169711B (fr) |
IE (1) | IE37998B1 (fr) |
IL (1) | IL40521A (fr) |
NL (1) | NL7214807A (fr) |
SE (1) | SE384856B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999043654A2 (fr) * | 1998-02-25 | 1999-09-02 | Genetics Institute, Inc. | Inhibiteurs d'enzymes phospholipases |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4022780A (en) * | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
FR2421900A1 (fr) * | 1977-03-17 | 1979-11-02 | Sauba Lab | Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques |
US4316847A (en) * | 1979-07-30 | 1982-02-23 | Hoffmann-La Roche Inc. | Pyrroles and pyrrolidines |
US4459227A (en) * | 1981-03-02 | 1984-07-10 | Duke University | Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones |
AU686843B2 (en) * | 1994-02-23 | 1998-02-12 | Pfizer Inc. | 4-heterocyclyl-substituted quinazoline derivatives, processes for their preparation and their use as anti-cancer agents |
US6252084B1 (en) * | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
SE0200356D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0201635D0 (sv) * | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
DK1471057T3 (da) | 2003-04-25 | 2006-05-15 | Actimis Pharmaceuticals Inc | Pyrimidinyleddikesyrederivater, der er egnede til behandlingen af sygdomme medieret af CRTH2 |
ATE372324T1 (de) * | 2003-04-30 | 2007-09-15 | Inst For Pharm Discovery Inc | Substituierte heteroarylverbindungen als inhibitoren von proteintyrosinphosphatasen |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
SI1718649T1 (sl) | 2004-01-31 | 2009-10-31 | Actimis Pharmaceuticals Inc | Derivati imidazo 1,2-c pirimidinilocetne kisline |
GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
UY29223A1 (es) | 2004-11-23 | 2006-06-30 | Astrazeneca Ab | Ácidos fenoxiacéticos sustituidos, composiciones farmacéuticas que los contienen y procesos para su preparación |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
JP5155171B2 (ja) | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
JP2009538289A (ja) | 2006-05-26 | 2009-11-05 | アストラゼネカ・アクチエボラーグ | ビアリールまたはヘテロアリール置換インドール |
DK2046740T3 (da) | 2006-07-22 | 2012-08-20 | Oxagen Ltd | Forbindelser med CRTH2-antagonistisk virkning |
UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
DK2205569T3 (da) | 2007-09-25 | 2012-05-21 | Actimis Pharmaceuticals Inc | Alkylthiopyrimidiner som crth2-antagonister |
AR068633A1 (es) | 2007-09-25 | 2009-11-25 | Actimis Pharmaceuticals Inc | Pirimidinas sustituidas con 2-s- bencilo como antagonistas de crth2 |
WO2009090414A1 (fr) | 2008-01-18 | 2009-07-23 | Oxagen Limited | Composés présentant une activité antagoniste de crth2 |
US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
JP2011509990A (ja) | 2008-01-22 | 2011-03-31 | オキサジェン リミテッド | Crth2アンタゴニスト活性を有する化合物 |
EP2240444A1 (fr) | 2008-01-22 | 2010-10-20 | Oxagen Limited | Composés présentant une activité antagoniste de crth2 |
GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
JP2022512588A (ja) * | 2018-10-05 | 2022-02-07 | バーテックス ファーマシューティカルズ インコーポレイテッド | アルファ1アンチトリプシンのモジュレーター |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL125443C (fr) * | 1963-06-06 |
-
0
- BE BE790679D patent/BE790679A/fr unknown
-
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
-
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx unknown
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
-
1973
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
-
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999043654A2 (fr) * | 1998-02-25 | 1999-09-02 | Genetics Institute, Inc. | Inhibiteurs d'enzymes phospholipases |
WO1999043654A3 (fr) * | 1998-02-25 | 1999-10-28 | Genetics Inst | Inhibiteurs d'enzymes phospholipases |
Also Published As
Publication number | Publication date |
---|---|
CA983932A (en) | 1976-02-17 |
FR2158464B1 (fr) | 1976-07-02 |
CH577499A5 (fr) | 1976-07-15 |
IE37998L (en) | 1973-05-03 |
HU169711B (fr) | 1977-02-28 |
AR203626A1 (es) | 1975-09-30 |
ES408226A1 (es) | 1976-02-01 |
IE37998B1 (en) | 1977-12-07 |
ES437311A1 (es) | 1977-04-01 |
SE384856B (sv) | 1976-05-24 |
BE790679A (fr) | 1973-04-27 |
IL40521A0 (en) | 1972-12-29 |
DD105611A5 (fr) | 1974-05-05 |
AR203627A1 (es) | 1975-09-30 |
JPS4856667A (fr) | 1973-08-09 |
DE2253927A1 (de) | 1973-05-10 |
NL7214807A (fr) | 1973-05-07 |
IL40521A (en) | 1975-06-25 |
US3884919A (en) | 1975-05-20 |
EG11358A (en) | 1977-02-28 |
GB1356834A (en) | 1974-06-19 |
AR198064A1 (es) | 1974-05-31 |
Similar Documents
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |