SE384856B - Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan - Google Patents
Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkanInfo
- Publication number
- SE384856B SE384856B SE7214215A SE1421572A SE384856B SE 384856 B SE384856 B SE 384856B SE 7214215 A SE7214215 A SE 7214215A SE 1421572 A SE1421572 A SE 1421572A SE 384856 B SE384856 B SE 384856B
- Authority
- SE
- Sweden
- Prior art keywords
- analgetic
- inflammatory
- way
- antipyretic effects
- preparing content
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1811672A GB1356834A (en) | 1971-11-03 | 1971-11-03 | Indole derivatives |
GB1811672 | 1972-04-19 | ||
GB3076772 | 1972-06-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE384856B true SE384856B (sv) | 1976-05-24 |
Family
ID=27257588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7214215A SE384856B (sv) | 1971-11-03 | 1972-11-02 | Sett att framstella indolderivat med anti-inflammatorisk, analgetisk och antipyretisk verkan |
Country Status (17)
Country | Link |
---|---|
US (1) | US3884919A (es) |
JP (1) | JPS4856667A (es) |
AR (3) | AR198064A1 (es) |
BE (1) | BE790679A (es) |
CA (1) | CA983932A (es) |
CH (1) | CH577499A5 (es) |
DD (1) | DD105611A5 (es) |
DE (1) | DE2253927A1 (es) |
EG (1) | EG11358A (es) |
ES (2) | ES408226A1 (es) |
FR (1) | FR2158464B1 (es) |
GB (1) | GB1356834A (es) |
HU (1) | HU169711B (es) |
IE (1) | IE37998B1 (es) |
IL (1) | IL40521A (es) |
NL (1) | NL7214807A (es) |
SE (1) | SE384856B (es) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4022780A (en) * | 1973-03-06 | 1977-05-10 | Imperial Chemical Industries Limited | Process for the manufacture of indole derivatives |
FR2421900A1 (fr) * | 1977-03-17 | 1979-11-02 | Sauba Lab | Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques |
US4316847A (en) * | 1979-07-30 | 1982-02-23 | Hoffmann-La Roche Inc. | Pyrroles and pyrrolidines |
US4459227A (en) * | 1981-03-02 | 1984-07-10 | Duke University | Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones |
JP2890267B2 (ja) * | 1994-02-23 | 1999-05-10 | ファイザー インク. | 4−ヘテロサイクリル−置換キナゾリン誘導体、その調製法および抗癌剤としてのその使用法 |
US6252084B1 (en) * | 1994-03-15 | 2001-06-26 | Eli Lilly And Company | 1H-indole-3-acetamide sPLA2 inhibitors |
CA2322162A1 (en) * | 1998-02-25 | 1999-09-02 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
US6500853B1 (en) | 1998-02-28 | 2002-12-31 | Genetics Institute, Llc | Inhibitors of phospholipase enzymes |
SE0200356D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0200411D0 (sv) * | 2002-02-05 | 2002-02-05 | Astrazeneca Ab | Novel use |
SE0201635D0 (sv) | 2002-05-30 | 2002-05-30 | Astrazeneca Ab | Novel compounds |
TW200307542A (en) | 2002-05-30 | 2003-12-16 | Astrazeneca Ab | Novel compounds |
SE0202241D0 (sv) | 2002-07-17 | 2002-07-17 | Astrazeneca Ab | Novel Compounds |
SE0301009D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
SE0301010D0 (sv) | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
EP1471057B1 (en) | 2003-04-25 | 2006-01-18 | Actimis Pharmaceuticals, Inc. | Pyrimidinylacetic acid derivatives useful for the treatment of diseases mediated by CRTH2 |
EP1618094B1 (en) * | 2003-04-30 | 2007-09-05 | The Institutes for Pharmaceutical Discovery, LLC | Substituted heteroaryls as inhibitors of protein tyrosine phosphatases |
SE0301569D0 (sv) | 2003-05-27 | 2003-05-27 | Astrazeneca Ab | Novel compounds |
SE0302232D0 (sv) * | 2003-08-18 | 2003-08-18 | Astrazeneca Ab | Novel Compounds |
SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
GB0324763D0 (en) | 2003-10-23 | 2003-11-26 | Oxagen Ltd | Use of compounds in therapy |
SE0303180D0 (sv) | 2003-11-26 | 2003-11-26 | Astrazeneca Ab | Novel compounds |
EP1718649B1 (en) | 2004-01-31 | 2009-06-10 | Actimis Pharmaceuticals, Inc., | Imidazo 1,2-c pyrimidinylacetic acid derivatives |
GB0415320D0 (en) | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
WO2006056752A1 (en) | 2004-11-23 | 2006-06-01 | Astrazeneca Ab | Phenoxyacetic acid derivatives useful for treating respiratory diseases |
GB0500604D0 (en) | 2005-01-13 | 2005-02-16 | Astrazeneca Ab | Novel process |
TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
JP5155171B2 (ja) | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
EP2125722A2 (en) | 2006-05-26 | 2009-12-02 | AstraZeneca AB | Bi-aryl or aryl-heteroaryl substituted indoles |
RU2458918C2 (ru) | 2006-07-22 | 2012-08-20 | Оксаген Лимитед | Соединения, обладающие антагонистической активностью по отношению к crth2 |
UA100983C2 (ru) | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
EP2205570B1 (en) | 2007-09-25 | 2013-09-11 | Actimis Pharmaceuticals, Inc., | 2-s-benzyl substituted pyrimidines as crth2 antagonists |
AU2008305632B2 (en) | 2007-09-25 | 2014-01-30 | Actimis Pharmaceuticals, Inc. | Alkylthio pyrimidines as CRTH2 antagonists |
RU2503672C2 (ru) | 2008-01-18 | 2014-01-10 | Оксаген Лимитед | Соединения, обладающие активностью антагонистов crth2 |
US7750027B2 (en) | 2008-01-18 | 2010-07-06 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
WO2009093029A1 (en) | 2008-01-22 | 2009-07-30 | Oxagen Limited | Compounds having crth2 antagonist activity |
EP2265581A1 (en) | 2008-01-22 | 2010-12-29 | Oxagen Limited | Compounds having crth2 antagonist activity |
GB201322273D0 (en) | 2013-12-17 | 2014-01-29 | Atopix Therapeutics Ltd | Process |
GB201407807D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
GB201407820D0 (en) | 2014-05-02 | 2014-06-18 | Atopix Therapeutics Ltd | Polymorphic form |
CN113164761A (zh) * | 2018-10-05 | 2021-07-23 | 弗特克斯药品有限公司 | α-1抗胰蛋白酶的调节剂 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL125443C (es) * | 1963-06-06 | |||
US3679692A (en) * | 1969-10-01 | 1972-07-25 | Mead Johnson & Co | Iminomethylindolines |
-
0
- BE BE790679D patent/BE790679A/xx unknown
-
1971
- 1971-11-03 GB GB1811672A patent/GB1356834A/en not_active Expired
-
1972
- 1972-09-28 IE IE1320/72A patent/IE37998B1/xx unknown
- 1972-09-29 CA CA152,944A patent/CA983932A/en not_active Expired
- 1972-10-06 IL IL40521A patent/IL40521A/xx unknown
- 1972-10-10 US US296202A patent/US3884919A/en not_active Expired - Lifetime
- 1972-10-27 AR AR244863A patent/AR198064A1/es active
- 1972-10-29 EG EG446/72A patent/EG11358A/xx active
- 1972-11-02 CH CH1597672A patent/CH577499A5/xx unknown
- 1972-11-02 JP JP47110172A patent/JPS4856667A/ja active Pending
- 1972-11-02 NL NL7214807A patent/NL7214807A/xx unknown
- 1972-11-02 FR FR7238836A patent/FR2158464B1/fr not_active Expired
- 1972-11-02 SE SE7214215A patent/SE384856B/xx unknown
- 1972-11-02 DD DD166646A patent/DD105611A5/xx unknown
- 1972-11-03 ES ES408226A patent/ES408226A1/es not_active Expired
- 1972-11-03 DE DE2253927A patent/DE2253927A1/de active Pending
- 1972-11-03 HU HUIE540A patent/HU169711B/hu unknown
-
1973
- 1973-07-31 AR AR249381A patent/AR203626A1/es active
- 1973-07-31 AR AR249382A patent/AR203627A1/es active
-
1975
- 1975-04-30 ES ES437331A patent/ES437311A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE790679A (fr) | 1973-04-27 |
IE37998L (en) | 1973-05-03 |
AR203627A1 (es) | 1975-09-30 |
IL40521A (en) | 1975-06-25 |
IE37998B1 (en) | 1977-12-07 |
NL7214807A (es) | 1973-05-07 |
IL40521A0 (en) | 1972-12-29 |
GB1356834A (en) | 1974-06-19 |
HU169711B (es) | 1977-02-28 |
CA983932A (en) | 1976-02-17 |
ES437311A1 (es) | 1977-04-01 |
ES408226A1 (es) | 1976-02-01 |
CH577499A5 (es) | 1976-07-15 |
EG11358A (en) | 1977-02-28 |
FR2158464A1 (es) | 1973-06-15 |
DE2253927A1 (de) | 1973-05-10 |
JPS4856667A (es) | 1973-08-09 |
AR203626A1 (es) | 1975-09-30 |
FR2158464B1 (es) | 1976-07-02 |
AR198064A1 (es) | 1974-05-31 |
DD105611A5 (es) | 1974-05-05 |
US3884919A (en) | 1975-05-20 |
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