SE384025B - Forfarande for framstellning av alfa-isomeren av dekansyreestern av 10-(3-(4-hydroxietyl-1-piperazinyl)-propyliden)-2-trifluormetyltiaxanten eller syraadditionssalter derav - Google Patents

Forfarande for framstellning av alfa-isomeren av dekansyreestern av 10-(3-(4-hydroxietyl-1-piperazinyl)-propyliden)-2-trifluormetyltiaxanten eller syraadditionssalter derav

Info

Publication number
SE384025B
SE384025B SE7008314A SE831470A SE384025B SE 384025 B SE384025 B SE 384025B SE 7008314 A SE7008314 A SE 7008314A SE 831470 A SE831470 A SE 831470A SE 384025 B SE384025 B SE 384025B
Authority
SE
Sweden
Prior art keywords
acid
trifluoromethyltia
axant
propylidene
alfa
Prior art date
Application number
SE7008314A
Other languages
English (en)
Swedish (sv)
Inventor
P V Petersen
T Ammitzboll
Original Assignee
Kefalas As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas As filed Critical Kefalas As
Publication of SE384025B publication Critical patent/SE384025B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7008314A 1969-06-20 1970-06-16 Forfarande for framstellning av alfa-isomeren av dekansyreestern av 10-(3-(4-hydroxietyl-1-piperazinyl)-propyliden)-2-trifluormetyltiaxanten eller syraadditionssalter derav SE384025B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83525069A 1969-06-20 1969-06-20

Publications (1)

Publication Number Publication Date
SE384025B true SE384025B (sv) 1976-04-12

Family

ID=25269034

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7008314A SE384025B (sv) 1969-06-20 1970-06-16 Forfarande for framstellning av alfa-isomeren av dekansyreestern av 10-(3-(4-hydroxietyl-1-piperazinyl)-propyliden)-2-trifluormetyltiaxanten eller syraadditionssalter derav

Country Status (13)

Country Link
US (1) US3681346A (da)
AT (1) AT294088B (da)
BE (1) BE752286A (da)
CH (1) CH534180A (da)
DK (1) DK128743B (da)
FI (1) FI51194C (da)
FR (1) FR2052997B1 (da)
GB (1) GB1275181A (da)
IE (1) IE34684B1 (da)
NL (1) NL7009000A (da)
NO (1) NO127970B (da)
SE (1) SE384025B (da)
ZA (1) ZA703914B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035503A (en) * 1973-11-30 1977-07-12 Kefalas A/S Xanthene and thioxanthene derivatives, compositions thereof and a method of preparation thereof
US4022896A (en) * 1973-11-30 1977-05-10 Kefalas A/S Xanthene and thioxanthene compositions and method of treating
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
US4107430A (en) * 1976-10-20 1978-08-15 Pfizer Inc. Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer
US4232021A (en) * 1979-01-25 1980-11-04 Kefalas A/S Anti-depressant methods
GB8628903D0 (en) * 1986-12-03 1987-01-07 Lunbeck A S H Neuroleptic compounds
ITMI20032024A1 (it) * 2003-10-17 2005-04-18 Laboratorio Chimico Int Spa Procedimento per la preparazione dello z-flupentixol
CN102002034B (zh) * 2009-08-28 2012-11-28 江苏恩华药业股份有限公司 盐酸氟哌噻吨异构体的分离方法
CN103804347B (zh) * 2012-11-09 2017-10-03 H.隆德贝克有限公司 制备含有氟哌噻吨的药物组合物的方法
CN104177330A (zh) * 2014-09-10 2014-12-03 宁辉 盐酸氟哌噻吨结晶化合物及其药物组合物
CN107987053B (zh) * 2017-12-08 2023-04-14 植恩生物技术股份有限公司 一种高纯度z型盐酸氟哌噻吨的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE585338A (da) * 1958-12-04
CH410002A (de) * 1959-06-30 1966-03-31 Hoffmann La Roche Verfahren zur cis-/trans-Isomerisierung von tricyclischen Verbindungen
US3282930A (en) * 1962-08-17 1966-11-01 Smith Kline French Lab Hydroxyalkylenepiperazine derivatives and analogs thereof
US3350268A (en) * 1965-07-01 1967-10-31 Squibb & Sons Inc Compositions and method of employing phenothiazine salts

Also Published As

Publication number Publication date
GB1275181A (en) 1972-05-24
DE2029084B2 (de) 1976-09-23
US3681346A (en) 1972-08-01
IE34684B1 (en) 1975-07-23
DE2029084A1 (de) 1971-01-07
FR2052997A1 (da) 1971-04-16
AT294088B (de) 1971-11-10
ZA703914B (en) 1971-02-24
FR2052997B1 (da) 1974-08-30
FI51194C (fi) 1976-11-10
NL7009000A (da) 1970-12-22
NO127970B (da) 1973-09-10
IE34684L (en) 1970-12-20
DK128743B (da) 1974-06-24
BE752286A (fr) 1970-12-01
CH534180A (de) 1973-02-28
FI51194B (da) 1976-08-02

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