BE752286A - Alpha-isomere de l'ester d'acide decanoique de 10-(3-(4- hydroxyethyl-1-piperazinyl) propylidene)-2-trifluoromethyl- thiaxanthene, ses sels d'addition acide et compositions formees a partir de ces composes - Google Patents

Alpha-isomere de l'ester d'acide decanoique de 10-(3-(4- hydroxyethyl-1-piperazinyl) propylidene)-2-trifluoromethyl- thiaxanthene, ses sels d'addition acide et compositions formees a partir de ces composes

Info

Publication number
BE752286A
BE752286A BE752286DA BE752286A BE 752286 A BE752286 A BE 752286A BE 752286D A BE752286D A BE 752286DA BE 752286 A BE752286 A BE 752286A
Authority
BE
Belgium
Prior art keywords
thiaxanthene
propylidene
piperazinyl
isomer
trifluoromethyl
Prior art date
Application number
Other languages
English (en)
French (fr)
Inventor
P V Petersen
Th Ammitzboll
Original Assignee
Kefalas As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas As filed Critical Kefalas As
Publication of BE752286A publication Critical patent/BE752286A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE752286D 1969-06-20 1970-06-19 Alpha-isomere de l'ester d'acide decanoique de 10-(3-(4- hydroxyethyl-1-piperazinyl) propylidene)-2-trifluoromethyl- thiaxanthene, ses sels d'addition acide et compositions formees a partir de ces composes BE752286A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83525069A 1969-06-20 1969-06-20

Publications (1)

Publication Number Publication Date
BE752286A true BE752286A (fr) 1970-12-01

Family

ID=25269034

Family Applications (1)

Application Number Title Priority Date Filing Date
BE752286D BE752286A (fr) 1969-06-20 1970-06-19 Alpha-isomere de l'ester d'acide decanoique de 10-(3-(4- hydroxyethyl-1-piperazinyl) propylidene)-2-trifluoromethyl- thiaxanthene, ses sels d'addition acide et compositions formees a partir de ces composes

Country Status (13)

Country Link
US (1) US3681346A (da)
AT (1) AT294088B (da)
BE (1) BE752286A (da)
CH (1) CH534180A (da)
DK (1) DK128743B (da)
FI (1) FI51194C (da)
FR (1) FR2052997B1 (da)
GB (1) GB1275181A (da)
IE (1) IE34684B1 (da)
NL (1) NL7009000A (da)
NO (1) NO127970B (da)
SE (1) SE384025B (da)
ZA (1) ZA703914B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022896A (en) * 1973-11-30 1977-05-10 Kefalas A/S Xanthene and thioxanthene compositions and method of treating
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
US4035503A (en) * 1973-11-30 1977-07-12 Kefalas A/S Xanthene and thioxanthene derivatives, compositions thereof and a method of preparation thereof
US4107430A (en) * 1976-10-20 1978-08-15 Pfizer Inc. Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer
US4232021A (en) * 1979-01-25 1980-11-04 Kefalas A/S Anti-depressant methods
GB8628903D0 (en) * 1986-12-03 1987-01-07 Lunbeck A S H Neuroleptic compounds
ITMI20032024A1 (it) * 2003-10-17 2005-04-18 Laboratorio Chimico Int Spa Procedimento per la preparazione dello z-flupentixol
CN102002034B (zh) * 2009-08-28 2012-11-28 江苏恩华药业股份有限公司 盐酸氟哌噻吨异构体的分离方法
CN103804347B (zh) * 2012-11-09 2017-10-03 H.隆德贝克有限公司 制备含有氟哌噻吨的药物组合物的方法
CN104177330A (zh) * 2014-09-10 2014-12-03 宁辉 盐酸氟哌噻吨结晶化合物及其药物组合物
CN107987053B (zh) * 2017-12-08 2023-04-14 植恩生物技术股份有限公司 一种高纯度z型盐酸氟哌噻吨的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE585338A (da) * 1958-12-04
CH410002A (de) * 1959-06-30 1966-03-31 Hoffmann La Roche Verfahren zur cis-/trans-Isomerisierung von tricyclischen Verbindungen
US3282930A (en) * 1962-08-17 1966-11-01 Smith Kline French Lab Hydroxyalkylenepiperazine derivatives and analogs thereof
US3350268A (en) * 1965-07-01 1967-10-31 Squibb & Sons Inc Compositions and method of employing phenothiazine salts

Also Published As

Publication number Publication date
FI51194B (da) 1976-08-02
FR2052997B1 (da) 1974-08-30
SE384025B (sv) 1976-04-12
IE34684B1 (en) 1975-07-23
FR2052997A1 (da) 1971-04-16
IE34684L (en) 1970-12-20
US3681346A (en) 1972-08-01
FI51194C (fi) 1976-11-10
CH534180A (de) 1973-02-28
GB1275181A (en) 1972-05-24
DK128743B (da) 1974-06-24
ZA703914B (en) 1971-02-24
AT294088B (de) 1971-11-10
DE2029084B2 (de) 1976-09-23
DE2029084A1 (de) 1971-01-07
NL7009000A (da) 1970-12-22
NO127970B (da) 1973-09-10

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Legal Events

Date Code Title Description
RE20 Patent expired

Owner name: KEFALAS A/S

Effective date: 19900619