IE34684L - Hydroxyethylpiperazinylpropylidenetrifluoromethyl¹thiaxanthene.¹e. - Google Patents

Hydroxyethylpiperazinylpropylidenetrifluoromethyl¹thiaxanthene.¹e.

Info

Publication number
IE34684L
IE34684L IE700772A IE77270A IE34684L IE 34684 L IE34684 L IE 34684L IE 700772 A IE700772 A IE 700772A IE 77270 A IE77270 A IE 77270A IE 34684 L IE34684 L IE 34684L
Authority
IE
Ireland
Prior art keywords
us3681346a
trifluoroemethyl
thiaxanthene
propylidene
piperazinyl
Prior art date
Application number
IE700772A
Other versions
IE34684B1 (en
Original Assignee
Kefalas As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kefalas As filed Critical Kefalas As
Publication of IE34684L publication Critical patent/IE34684L/en
Publication of IE34684B1 publication Critical patent/IE34684B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is concerned with the alpha -isomer of the decanoic acid ester of 10-[3-(4-hydroxyethyl-1-piperazinyl)propylidene]-2-trifluoroemethyl thiaxanthene, the non-toxic acid addition salts thereof, methods of preparing the same, therapeutic compositions thereof having prolonged effect, and a method of treating psychotic patients therewith. [US3681346A]
IE772/70A 1969-06-20 1970-06-15 Hydroxyethylpiperazinylpropylidenetrifluoromethyl-thiaxanthene IE34684B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83525069A 1969-06-20 1969-06-20

Publications (2)

Publication Number Publication Date
IE34684L true IE34684L (en) 1970-12-20
IE34684B1 IE34684B1 (en) 1975-07-23

Family

ID=25269034

Family Applications (1)

Application Number Title Priority Date Filing Date
IE772/70A IE34684B1 (en) 1969-06-20 1970-06-15 Hydroxyethylpiperazinylpropylidenetrifluoromethyl-thiaxanthene

Country Status (13)

Country Link
US (1) US3681346A (en)
AT (1) AT294088B (en)
BE (1) BE752286A (en)
CH (1) CH534180A (en)
DK (1) DK128743B (en)
FI (1) FI51194C (en)
FR (1) FR2052997B1 (en)
GB (1) GB1275181A (en)
IE (1) IE34684B1 (en)
NL (1) NL7009000A (en)
NO (1) NO127970B (en)
SE (1) SE384025B (en)
ZA (1) ZA703914B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035503A (en) * 1973-11-30 1977-07-12 Kefalas A/S Xanthene and thioxanthene derivatives, compositions thereof and a method of preparation thereof
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
US4022896A (en) * 1973-11-30 1977-05-10 Kefalas A/S Xanthene and thioxanthene compositions and method of treating
US4107430A (en) * 1976-10-20 1978-08-15 Pfizer Inc. Conversion of trans- to cis-N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-thioxanthene-2-sulfonamide and recovery of the cis-isomer
US4232021A (en) * 1979-01-25 1980-11-04 Kefalas A/S Anti-depressant methods
GB8628903D0 (en) * 1986-12-03 1987-01-07 Lunbeck A S H Neuroleptic compounds
ITMI20032024A1 (en) * 2003-10-17 2005-04-18 Laboratorio Chimico Int Spa PROCEDURE FOR THE PREPARATION OF Z-FLUPENTIXOL
CN102002034B (en) * 2009-08-28 2012-11-28 江苏恩华药业股份有限公司 Method for separating flupentixol hydrochloride isomers
CN103804347B (en) * 2012-11-09 2017-10-03 H.隆德贝克有限公司 The method for preparing the pharmaceutical composition containing Flupentixol
CN104177330A (en) * 2014-09-10 2014-12-03 宁辉 Flupentixol dihydrochloride crystal compound and pharmaceutical composition thereof
CN107987053B (en) * 2017-12-08 2023-04-14 植恩生物技术股份有限公司 Preparation method of high-purity Z-type flupentixol hydrochloride

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE585338A (en) * 1958-12-04
CH410002A (en) * 1959-06-30 1966-03-31 Hoffmann La Roche Process for the cis / trans isomerization of tricyclic compounds
US3282930A (en) * 1962-08-17 1966-11-01 Smith Kline French Lab Hydroxyalkylenepiperazine derivatives and analogs thereof
US3350268A (en) * 1965-07-01 1967-10-31 Squibb & Sons Inc Compositions and method of employing phenothiazine salts

Also Published As

Publication number Publication date
IE34684B1 (en) 1975-07-23
ZA703914B (en) 1971-02-24
FR2052997B1 (en) 1974-08-30
NL7009000A (en) 1970-12-22
DE2029084B2 (en) 1976-09-23
FR2052997A1 (en) 1971-04-16
FI51194B (en) 1976-08-02
FI51194C (en) 1976-11-10
SE384025B (en) 1976-04-12
US3681346A (en) 1972-08-01
AT294088B (en) 1971-11-10
BE752286A (en) 1970-12-01
GB1275181A (en) 1972-05-24
DE2029084A1 (en) 1971-01-07
NO127970B (en) 1973-09-10
CH534180A (en) 1973-02-28
DK128743B (en) 1974-06-24

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