SE0200919D0 - Chemical compounds - Google Patents
Chemical compoundsInfo
- Publication number
- SE0200919D0 SE0200919D0 SE0200919A SE0200919A SE0200919D0 SE 0200919 D0 SE0200919 D0 SE 0200919D0 SE 0200919 A SE0200919 A SE 0200919A SE 0200919 A SE0200919 A SE 0200919A SE 0200919 D0 SE0200919 D0 SE 0200919D0
- Authority
- SE
- Sweden
- Prior art keywords
- sup
- chemical compounds
- activity
- compounds
- solvate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0200919A SE0200919D0 (sv) | 2002-03-25 | 2002-03-25 | Chemical compounds |
TW092105784A TW200305417A (en) | 2002-03-25 | 2003-03-17 | Chemical compounds |
KR10-2004-7015310A KR20040094876A (ko) | 2002-03-25 | 2003-03-24 | 케모킨 수용체 활성 (특히 ccr5)의 조절제로서 유용한피페리딘 또는 8-아자-바이시클로[3.2.1]옥트-3-일 유도체 |
PCT/SE2003/000480 WO2003080574A1 (fr) | 2002-03-25 | 2003-03-24 | Derives de piperidine ou 8-aza-bicyclo[3.2.1]oct-3-yle convenant comme modulateurs de l'activite des recepteurs de la chimiokine (plus paritculierement ccr5) |
EP03745059A EP1490336A1 (fr) | 2002-03-25 | 2003-03-24 | Derives de piperidine ou 8-aza-bicyclo(3.2.1)oct-3-yle convenant comme modulateurs de l'activite des recepteurs de la chimiokine (plus paritculierement ccr5) |
JP2003578329A JP2005526797A (ja) | 2002-03-25 | 2003-03-24 | ケモカイン受容体活性(特にccr5)のモジュレーターとして有用なピペリジンまたは8−アザ−ビシクロ[3.2.1]オクタ−3−イル誘導体 |
AU2003216012A AU2003216012A1 (en) | 2002-03-25 | 2003-03-24 | Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially CCR5) |
CNA038064642A CN1642913A (zh) | 2002-03-25 | 2003-03-24 | 用作趋化因子受体活性(尤其是ccr5)调节剂的哌啶或8-氮杂-二环[3.2.1]辛-3-基衍生物 |
BR0308592-9A BR0308592A (pt) | 2002-03-25 | 2003-03-24 | Derivados de piperidina ou 8-azabiciclo [3.2.1] oct-3-il-piperidina, de utilidade como moduladores da atividade do receptor de quimocina (especialmente ccr5) |
MXPA04009162A MXPA04009162A (es) | 2002-03-25 | 2003-03-24 | Derivados de piperidina u 8-aza-biciclo[3.2.1]oct-3-ilo empleados como moduladores de actividad del receptor de quimiocina (especialmente ccr5). |
CA002479887A CA2479887A1 (fr) | 2002-03-25 | 2003-03-24 | Derives de piperidine ou 8-aza-bicyclo¬3.2.1|oct-3-yle convenant comme modulateurs de l'activite des recepteurs de la chimiokine (plus paritculierement ccr5) |
IL16389603A IL163896A0 (en) | 2002-03-25 | 2003-03-24 | Piperidine or 8-aza-bicycloÄ3.2.1Üoct-3-yl derivatives useful as modulators of chemokine receptoractivity (especially ccr5) |
US10/508,895 US20050171353A1 (en) | 2002-03-25 | 2003-03-24 | Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially ccr5) |
ARP030101026A AR039125A1 (es) | 2002-03-25 | 2003-03-25 | Derivados de piperidina o 8-aza-biciclo(3.2.1.)octa-3-il derivados, utiles como moduladores de receptores de actividad de quemoquinas |
ZA200407414A ZA200407414B (en) | 2002-03-25 | 2004-09-15 | Piperidine or 8-aza-bicyclo[3.2.1]oct-3-yl derivatives useful as modulators of chemokine receptor activity (especially CCR5). |
NO20044545A NO20044545L (no) | 2002-03-25 | 2004-10-22 | Piperidin-eller 8-aza-bicyklo[3.2.1.]okt-3-yl derivater som er nyttige som modulatorer for kemokireseptoraktivitet (spesielt CCR5) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0200919A SE0200919D0 (sv) | 2002-03-25 | 2002-03-25 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SE0200919D0 true SE0200919D0 (sv) | 2002-03-25 |
Family
ID=20287391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE0200919A SE0200919D0 (sv) | 2002-03-25 | 2002-03-25 | Chemical compounds |
Country Status (16)
Country | Link |
---|---|
US (1) | US20050171353A1 (fr) |
EP (1) | EP1490336A1 (fr) |
JP (1) | JP2005526797A (fr) |
KR (1) | KR20040094876A (fr) |
CN (1) | CN1642913A (fr) |
AR (1) | AR039125A1 (fr) |
AU (1) | AU2003216012A1 (fr) |
BR (1) | BR0308592A (fr) |
CA (1) | CA2479887A1 (fr) |
IL (1) | IL163896A0 (fr) |
MX (1) | MXPA04009162A (fr) |
NO (1) | NO20044545L (fr) |
SE (1) | SE0200919D0 (fr) |
TW (1) | TW200305417A (fr) |
WO (1) | WO2003080574A1 (fr) |
ZA (1) | ZA200407414B (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR028948A1 (es) | 2000-06-20 | 2003-05-28 | Astrazeneca Ab | Compuestos novedosos |
SE0301369D0 (sv) * | 2003-05-09 | 2003-05-09 | Astrazeneca Ab | Chemical compounds |
SE0302090D0 (sv) * | 2003-07-16 | 2003-07-16 | Astrazeneca Ab | Chemical compounds |
US7498346B2 (en) * | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
SE0303396D0 (sv) * | 2003-12-16 | 2003-12-16 | Astrazeneca Ab | Chemical compounds |
TW200538098A (en) * | 2004-03-22 | 2005-12-01 | Astrazeneca Ab | Therapeutic agents |
ES2277745B1 (es) * | 2005-06-14 | 2008-06-01 | Laboratorios Almirall S.A. | Derivados n-amida de 8-azabiciclo /3.2.1/oct-3-ilo como antagonistas de ccr1. |
WO2006138350A2 (fr) * | 2005-06-15 | 2006-12-28 | Anormed Inc. | Composes de liaison au recepteur de la chimiokine |
WO2007015664A1 (fr) * | 2005-08-01 | 2007-02-08 | Astrazeneca Ab | Nouveaux dérivés de pipéridine en tant que modulateurs de récepteur de chimiokine utiles pour le traitement des affections respiratoires |
CN101291905A (zh) | 2005-10-19 | 2008-10-22 | 弗·哈夫曼-拉罗切有限公司 | 苯乙酰胺nnrt抑制剂 |
ES2360893T3 (es) | 2006-08-16 | 2011-06-10 | F. Hoffmann-La Roche Ag | Inhibidores no nucleósidos de la transcriptasa inversa. |
RU2469032C2 (ru) | 2006-12-13 | 2012-12-10 | Ф.Хоффманн-Ля Рош Аг | Производные 2-(пиперидин-4-ил)-4-фенокси- или фениламинопиримидина в качестве ненуклеозидных ингибиторов обратной транскриптазы |
EP2173715A2 (fr) * | 2007-07-13 | 2010-04-14 | Euroscreen S.A. | Utilisation des dérivés de pipéridine en tant que agonistes de l'activité des récepteurs de chimiokine |
CN101412692B (zh) * | 2007-10-18 | 2012-10-17 | 中国科学院上海药物研究所 | 1-(3-氨基丙基)哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途 |
CN101712679B (zh) | 2008-10-08 | 2013-04-10 | 中国科学院上海药物研究所 | 一种酰胺类化合物、其药物组合物及其制备方法和用途 |
CN102140104B (zh) * | 2010-02-03 | 2014-11-12 | 中国科学院上海药物研究所 | 1-(3-(s)-氨基丙基)-哌啶-4-氨基酰胺类化合物、其药物组合物及其制备方法和用途 |
WO2012113103A1 (fr) | 2011-02-25 | 2012-08-30 | Helsinn Healthcare S.A. | Urées asymétriques et leurs utilisations médicales |
CN106977511B (zh) * | 2011-12-19 | 2019-04-12 | 中国科学院上海药物研究所 | 一种氨基丙基取代托烷胺类化合物、其药物组合物及其制备方法和用途 |
SI3390355T1 (sl) | 2016-03-22 | 2023-07-31 | Helsinn Healthcare S. A. | Benzensulfonil-asimetrične sečnine in njihove medicinske uporabe |
US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1013276A1 (fr) * | 1998-12-23 | 2000-06-28 | Pfizer Inc. | Aminoazacycloalcanes comme modulateurs de CCR5 |
AU5473800A (en) * | 1999-06-11 | 2001-01-02 | Merck & Co., Inc. | Cyclopentyl modulators of chemokine receptor activity |
SE9902987D0 (sv) * | 1999-08-24 | 1999-08-24 | Astra Pharma Prod | Novel compounds |
GB0011838D0 (en) * | 2000-05-17 | 2000-07-05 | Astrazeneca Ab | Chemical compounds |
SK286129B6 (sk) * | 2000-05-26 | 2008-04-07 | Pfizer Inc. | Tropánové deriváty, ich použitie, spôsob a medziprodukt na ich výrobu, kombinácia a farmaceutická kompozícia s ich obsahom |
WO2002070479A1 (fr) * | 2001-03-01 | 2002-09-12 | Astrazeneca Ab | Composes de n-4-piperidinyle en tant que modulateurs ccr5 |
GB0107228D0 (en) * | 2001-03-22 | 2001-05-16 | Astrazeneca Ab | Chemical compounds |
-
2002
- 2002-03-25 SE SE0200919A patent/SE0200919D0/xx unknown
-
2003
- 2003-03-17 TW TW092105784A patent/TW200305417A/zh unknown
- 2003-03-24 KR KR10-2004-7015310A patent/KR20040094876A/ko not_active Application Discontinuation
- 2003-03-24 CN CNA038064642A patent/CN1642913A/zh active Pending
- 2003-03-24 MX MXPA04009162A patent/MXPA04009162A/es not_active Application Discontinuation
- 2003-03-24 IL IL16389603A patent/IL163896A0/xx unknown
- 2003-03-24 CA CA002479887A patent/CA2479887A1/fr not_active Abandoned
- 2003-03-24 BR BR0308592-9A patent/BR0308592A/pt not_active Application Discontinuation
- 2003-03-24 AU AU2003216012A patent/AU2003216012A1/en not_active Abandoned
- 2003-03-24 WO PCT/SE2003/000480 patent/WO2003080574A1/fr active Application Filing
- 2003-03-24 EP EP03745059A patent/EP1490336A1/fr not_active Withdrawn
- 2003-03-24 US US10/508,895 patent/US20050171353A1/en not_active Abandoned
- 2003-03-24 JP JP2003578329A patent/JP2005526797A/ja active Pending
- 2003-03-25 AR ARP030101026A patent/AR039125A1/es unknown
-
2004
- 2004-09-15 ZA ZA200407414A patent/ZA200407414B/en unknown
- 2004-10-22 NO NO20044545A patent/NO20044545L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2003080574A1 (fr) | 2003-10-02 |
CN1642913A (zh) | 2005-07-20 |
JP2005526797A (ja) | 2005-09-08 |
BR0308592A (pt) | 2005-02-09 |
TW200305417A (en) | 2003-11-01 |
EP1490336A1 (fr) | 2004-12-29 |
AR039125A1 (es) | 2005-02-09 |
ZA200407414B (en) | 2005-08-29 |
AU2003216012A1 (en) | 2003-10-08 |
KR20040094876A (ko) | 2004-11-10 |
MXPA04009162A (es) | 2004-12-07 |
IL163896A0 (en) | 2005-12-18 |
NO20044545L (no) | 2004-12-13 |
CA2479887A1 (fr) | 2003-10-02 |
US20050171353A1 (en) | 2005-08-04 |
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