SA523440271B1 - تركيبات مناسبة للاستخدام في حديثي الولادة - Google Patents

تركيبات مناسبة للاستخدام في حديثي الولادة

Info

Publication number
SA523440271B1
SA523440271B1 SA523440271A SA523440271A SA523440271B1 SA 523440271 B1 SA523440271 B1 SA 523440271B1 SA 523440271 A SA523440271 A SA 523440271A SA 523440271 A SA523440271 A SA 523440271A SA 523440271 B1 SA523440271 B1 SA 523440271B1
Authority
SA
Saudi Arabia
Prior art keywords
methods
ivh
bpd
cld
insulin
Prior art date
Application number
SA523440271A
Other languages
Arabic (ar)
English (en)
Inventor
إندرانيل بهاتاشاريا،
كاثرين تايلور،
ليندا هان،
نازيلا سالامات-ميلير،
بينغ هي،
بينيتا أمسدين،
جيمس كرانز،
Original Assignee
أوه إيه كيه هيل بيو ليمتد
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by أوه إيه كيه هيل بيو ليمتد filed Critical أوه إيه كيه هيل بيو ليمتد
Publication of SA523440271B1 publication Critical patent/SA523440271B1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754Insulin-like growth factor binding proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SA523440271A 2020-10-19 2023-04-06 تركيبات مناسبة للاستخدام في حديثي الولادة SA523440271B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063093696P 2020-10-19 2020-10-19
PCT/US2021/055598 WO2022086953A1 (en) 2020-10-19 2021-10-19 Compositions suitable for use in neonates

Publications (1)

Publication Number Publication Date
SA523440271B1 true SA523440271B1 (ar) 2025-04-10

Family

ID=78622033

Family Applications (1)

Application Number Title Priority Date Filing Date
SA523440271A SA523440271B1 (ar) 2020-10-19 2023-04-06 تركيبات مناسبة للاستخدام في حديثي الولادة

Country Status (24)

Country Link
US (1) US20230381285A1 (enExample)
EP (2) EP4534073A3 (enExample)
JP (1) JP7827315B2 (enExample)
KR (1) KR20230113287A (enExample)
CN (1) CN117098547A (enExample)
AU (1) AU2021364523A1 (enExample)
CA (1) CA3194764A1 (enExample)
DK (1) DK4228676T3 (enExample)
ES (1) ES3005966T3 (enExample)
FI (1) FI4228676T3 (enExample)
HR (1) HRP20250193T1 (enExample)
HU (1) HUE070409T2 (enExample)
IL (1) IL301688A (enExample)
LT (1) LT4228676T (enExample)
MX (1) MX2023004426A (enExample)
PL (1) PL4228676T3 (enExample)
PT (1) PT4228676T (enExample)
RS (1) RS66493B1 (enExample)
SA (1) SA523440271B1 (enExample)
SI (1) SI4228676T1 (enExample)
SM (1) SMT202500093T1 (enExample)
TW (1) TWI912393B (enExample)
WO (1) WO2022086953A1 (enExample)
ZA (1) ZA202303162B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025502349A (ja) 2022-01-19 2025-01-24 オーク ヒル バイオ リミテッド Igf-1/igfbpの酸化を低減するための組成物および方法
IL316413A (en) 2022-05-04 2024-12-01 Oak Hill Bio Ltd Combination therapy for preterm infants
WO2023242439A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
KR20250079196A (ko) * 2022-10-04 2025-06-04 오크 힐 바이오 리미티드 Igf-1 복합체를 이용한 신생아 치료 방법

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
AU627423B2 (en) 1987-04-06 1992-08-27 Celtrix Pharmaceuticals, Inc. Human somatomedin carrier protein subunits and process for producing them
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
DE3854842T2 (de) 1988-04-12 1996-06-13 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
GB8826451D0 (en) 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
AU4238493A (en) 1992-05-08 1993-12-13 Thomas Jefferson University IGF-1 analogs
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
US5985830A (en) * 1996-09-16 1999-11-16 Dalhousie University Use of IGF-I for the treatment of kidney disorders
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6436897B2 (en) * 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US20020028764A1 (en) * 2000-09-04 2002-03-07 Aarhus Amt. Treatment of acute and chronic liver disease
WO2006138181A2 (en) * 2005-06-14 2006-12-28 Amgen Inc. Self-buffering protein formulations
EP2501367B1 (en) * 2009-11-17 2015-01-21 Ipsen Pharma S.A.S. Formulation for HGH and RHIGF-1 combination
HK1217633A1 (zh) * 2013-01-15 2017-01-20 Teva Pharmaceutical Industries Ltd. 冻乾方法
KR20140119396A (ko) * 2013-03-29 2014-10-10 삼성전자주식회사 단백질 약물의 액상 제형
KR20200097679A (ko) * 2017-09-11 2020-08-19 샤이어 휴먼 지네틱 테라피즈 인크. 만성 폐 질환 치료를 위한 방법 및 조성물
JP2025502349A (ja) * 2022-01-19 2025-01-24 オーク ヒル バイオ リミテッド Igf-1/igfbpの酸化を低減するための組成物および方法
WO2023139250A1 (en) * 2022-01-24 2023-07-27 Oak Hill Bio Limited Lot release assays for igf‐1/igfbp complexes

Also Published As

Publication number Publication date
DK4228676T3 (da) 2025-01-20
ES3005966T3 (en) 2025-03-17
HUE070409T2 (hu) 2025-06-28
SI4228676T1 (sl) 2025-03-31
ZA202303162B (en) 2024-08-28
WO2022086953A9 (en) 2022-07-07
CN117098547A (zh) 2023-11-21
RS66493B1 (sr) 2025-03-31
JP7827315B2 (ja) 2026-03-10
FI4228676T3 (fi) 2025-02-26
US20230381285A1 (en) 2023-11-30
HRP20250193T1 (hr) 2025-04-11
PT4228676T (pt) 2025-01-24
IL301688A (en) 2023-05-01
KR20230113287A (ko) 2023-07-28
JP2023550203A (ja) 2023-11-30
EP4228676B1 (en) 2025-01-08
EP4534073A3 (en) 2025-05-14
MX2023004426A (es) 2023-08-04
LT4228676T (lt) 2025-02-10
WO2022086953A1 (en) 2022-04-28
TWI912393B (zh) 2026-01-21
AU2021364523A1 (en) 2023-04-06
SMT202500093T1 (it) 2025-03-12
EP4534073A2 (en) 2025-04-09
PL4228676T3 (pl) 2025-04-07
EP4228676A1 (en) 2023-08-23
TW202233228A (zh) 2022-09-01
CA3194764A1 (en) 2022-04-28

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