SA523440271B1 - تركيبات مناسبة للاستخدام في حديثي الولادة - Google Patents

تركيبات مناسبة للاستخدام في حديثي الولادة

Info

Publication number
SA523440271B1
SA523440271B1 SA523440271A SA523440271A SA523440271B1 SA 523440271 B1 SA523440271 B1 SA 523440271B1 SA 523440271 A SA523440271 A SA 523440271A SA 523440271 A SA523440271 A SA 523440271A SA 523440271 B1 SA523440271 B1 SA 523440271B1
Authority
SA
Saudi Arabia
Prior art keywords
formulation
aaa
ااا
approximately
igf
Prior art date
Application number
SA523440271A
Other languages
Arabic (ar)
English (en)
Inventor
إندرانيل بهاتاشاريا،
كاثرين تايلور،
ليندا هان،
نازيلا سالامات-ميلير،
بينغ هي،
بينيتا أمسدين،
جيمس كرانز،
Original Assignee
أوه إيه كيه هيل بيو ليمتد
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by أوه إيه كيه هيل بيو ليمتد filed Critical أوه إيه كيه هيل بيو ليمتد
Publication of SA523440271B1 publication Critical patent/SA523440271B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754—Insulin-like growth factor binding proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SA523440271A 2020-10-19 2023-04-06 تركيبات مناسبة للاستخدام في حديثي الولادة SA523440271B1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063093696P 2020-10-19 2020-10-19
PCT/US2021/055598 WO2022086953A1 (en) 2020-10-19 2021-10-19 Compositions suitable for use in neonates

Publications (1)

Publication Number Publication Date
SA523440271B1 true SA523440271B1 (ar) 2025-04-10

Family

ID=78622033

Family Applications (1)

Application Number Title Priority Date Filing Date
SA523440271A SA523440271B1 (ar) 2020-10-19 2023-04-06 تركيبات مناسبة للاستخدام في حديثي الولادة

Country Status (24)

Country Link
US (1) US20230381285A1 (cg-RX-API-DMAC10.html)
EP (2) EP4228676B1 (cg-RX-API-DMAC10.html)
JP (2) JP7827315B2 (cg-RX-API-DMAC10.html)
KR (1) KR20230113287A (cg-RX-API-DMAC10.html)
CN (1) CN117098547A (cg-RX-API-DMAC10.html)
AU (1) AU2021364523A1 (cg-RX-API-DMAC10.html)
CA (1) CA3194764A1 (cg-RX-API-DMAC10.html)
DK (1) DK4228676T3 (cg-RX-API-DMAC10.html)
ES (1) ES3005966T3 (cg-RX-API-DMAC10.html)
FI (1) FI4228676T3 (cg-RX-API-DMAC10.html)
HR (1) HRP20250193T1 (cg-RX-API-DMAC10.html)
HU (1) HUE070409T2 (cg-RX-API-DMAC10.html)
IL (1) IL301688A (cg-RX-API-DMAC10.html)
LT (1) LT4228676T (cg-RX-API-DMAC10.html)
MX (1) MX2023004426A (cg-RX-API-DMAC10.html)
PL (1) PL4228676T3 (cg-RX-API-DMAC10.html)
PT (1) PT4228676T (cg-RX-API-DMAC10.html)
RS (1) RS66493B1 (cg-RX-API-DMAC10.html)
SA (1) SA523440271B1 (cg-RX-API-DMAC10.html)
SI (1) SI4228676T1 (cg-RX-API-DMAC10.html)
SM (1) SMT202500093T1 (cg-RX-API-DMAC10.html)
TW (1) TWI912393B (cg-RX-API-DMAC10.html)
WO (1) WO2022086953A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA202303162B (cg-RX-API-DMAC10.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250099541A1 (en) 2022-01-19 2025-03-27 Oak Hill Bio Ltd Compositions and methods for reducing oxidation of igf-1/igfbp
CA3248280A1 (en) 2022-05-04 2023-11-09 Oak Hill Bio Limited POLYTHERAPY FOR PREMATURE INFANTS
WO2023242439A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Vascular stabilisation (preterm infants)
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants
EP4598630A1 (en) * 2022-10-04 2025-08-13 Oak Hill Bio Limited Method of treating neonates with igf-1 complex

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
ATE90690T1 (de) 1987-04-06 1993-07-15 Celtrix Pharma Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
ATE132164T1 (de) 1988-04-12 1996-01-15 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
GB8826451D0 (en) 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
EP0639981A4 (en) 1992-05-08 1995-06-28 Univ Jefferson ANALOGS OF THE IGF FACTOR (01/18/94).
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US5783556A (en) * 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
EP0956041A1 (en) * 1996-09-16 1999-11-17 Dalhousie University Use of igf-i for the treatment of polycystic kidney disease and related indications
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6436897B2 (en) * 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US20020028764A1 (en) * 2000-09-04 2002-03-07 Aarhus Amt. Treatment of acute and chronic liver disease
JP2008543839A (ja) * 2005-06-14 2008-12-04 アムジェン インコーポレーテッド 自己緩衝タンパク質製剤
RU2558821C2 (ru) * 2009-11-17 2015-08-10 Ипсен Фарма С.А.С. ЛЕКАРСТВЕННАЯ ФОРМА ДЛЯ КОМБИНАЦИИ hGH И rhIGF-1
US20110152188A1 (en) * 2009-12-23 2011-06-23 Hanns-Christian Mahler Pharmaceutical compositions of igf/i proteins
CA2897062A1 (en) * 2013-01-15 2014-07-24 Teva Pharmaceutical Industries Ltd. Lyophilization process
KR20140119396A (ko) * 2013-03-29 2014-10-10 삼성전자주식회사 단백질 약물의 액상 제형
EP3681602B1 (en) * 2017-09-11 2026-04-15 Oak Hill Bio Limited Compositions for reducing the incidence of bpd
US20250099541A1 (en) * 2022-01-19 2025-03-27 Oak Hill Bio Ltd Compositions and methods for reducing oxidation of igf-1/igfbp
WO2023139250A1 (en) * 2022-01-24 2023-07-27 Oak Hill Bio Limited Lot release assays for igf‐1/igfbp complexes

Also Published As

Publication number Publication date
PT4228676T (pt) 2025-01-24
JP2026102579A (ja) 2026-06-23
SMT202500093T1 (it) 2025-03-12
IL301688A (en) 2023-05-01
WO2022086953A9 (en) 2022-07-07
AU2021364523A1 (en) 2023-04-06
JP2023550203A (ja) 2023-11-30
ES3005966T3 (en) 2025-03-17
MX2023004426A (es) 2023-08-04
LT4228676T (lt) 2025-02-10
CN117098547A (zh) 2023-11-21
HUE070409T2 (hu) 2025-06-28
HRP20250193T1 (hr) 2025-04-11
EP4534073A2 (en) 2025-04-09
EP4228676A1 (en) 2023-08-23
US20230381285A1 (en) 2023-11-30
SI4228676T1 (sl) 2025-03-31
WO2022086953A1 (en) 2022-04-28
TWI912393B (zh) 2026-01-21
KR20230113287A (ko) 2023-07-28
FI4228676T3 (fi) 2025-02-26
CA3194764A1 (en) 2022-04-28
EP4534073A3 (en) 2025-05-14
RS66493B1 (sr) 2025-03-31
DK4228676T3 (da) 2025-01-20
PL4228676T3 (pl) 2025-04-07
EP4228676B1 (en) 2025-01-08
JP7827315B2 (ja) 2026-03-10
ZA202303162B (en) 2024-08-28
TW202233228A (zh) 2022-09-01

Similar Documents

Publication Publication Date Title
ZA202303162B (en) Compositions suitable for use in neonates
DK2438086T3 (en) Enhanced reconstituted surfactant composition containing analogues of surfactant protein B (SP-B) and surfactant protein C (SP-C)
EP2152288B1 (en) Reconstituted surfactants having improved properties
CA2891933C (en) Recombinant pulmonary surfactants comprising sp-b and sp-c analogues and a phospholipid mixture
JP5405307B2 (ja) 改善された性質を有する再構成サーファクタント
JPH03500768A (ja) 肺異常治療のための方法および組成物
JP2001512452A (ja) 3−(シクロプロピルメトキシ)−n−(3,5−ジクロロ−4−ピリジニル)−4−(ジフルオロメトキシ)ベンズアミド及び肺表面活性物質を含有する、ardsまたはirdsの治療のための組成物
ES2315255T3 (es) Utilizacion de trombopoyetina como medicamento para la terapia y la prevencion de trombocitopenia.
JP2023550203A5 (cg-RX-API-DMAC10.html)
JP2023113852A (ja) 進行性のbpdの処置のための肺サーファクタント及びステロイドを含む処置的組み合わせ物
EP1131055B1 (en) Treatment set containing lungsurfactant compositions
Chotigeat et al. Inhaled iloprost for severe persistent pulmonary hypertension of the newborn
EP1320384B1 (en) The synergetic effects of hgf and antibacterial treatment
US10543256B2 (en) Stable pharmaceutical formulation comprising a reconstituted pulmonary surfactant composition
US20050244508A1 (en) Anti-spasmodic comprising xenon
JP2008543790A (ja) 短腸症候群の治療
WO2005105111A1 (ja) 人工肺サーファクタント組成物およびその使用方法
CA2428937A1 (en) Method for treating respiratory distress syndrome using leptin
US6838441B1 (en) Albumin for treating meconium aspiration syndrome
US20030032598A1 (en) Method to treat pulmonary hypoplasia in the newborn
Novick et al. Use of epoetin (erythropoietin) in the anemia of prematurity
NZ739899B2 (en) Biopharmaceutical compositions