SA520412155B1 - مشتقات إيميدازوبيريدين واستخدامها كدواء - Google Patents
مشتقات إيميدازوبيريدين واستخدامها كدواءInfo
- Publication number
- SA520412155B1 SA520412155B1 SA520412155A SA520412155A SA520412155B1 SA 520412155 B1 SA520412155 B1 SA 520412155B1 SA 520412155 A SA520412155 A SA 520412155A SA 520412155 A SA520412155 A SA 520412155A SA 520412155 B1 SA520412155 B1 SA 520412155B1
- Authority
- SA
- Saudi Arabia
- Prior art keywords
- medicament
- imidazopyridine derivatives
- associ
- ation
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Plant Substances (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
يتعلق الاختراع الحالي بمركبات إيميدازوبيريدين imidazopyridines جديدة من الصيغة العامة A A، بعمليات لتحضيرها، بتركيبات صيدلانية pharmaceutical compositions محتوية عليها واستخدامها في علاج، تحديداً معالجة أو الوقاية من حالات لها ارتباط مع خواص تعديل تفارغية سالبة مستقبل N- ميثيل- D- أسبارتات من النوع الفرعي 2ب N-methyl D-aspartate receptor subtype 2B (NR2B).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17206152 | 2017-12-08 | ||
| PCT/EP2018/083728 WO2019110703A1 (en) | 2017-12-08 | 2018-12-06 | Imidazopyridine derivatives and the use thereof as medicament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SA520412155B1 true SA520412155B1 (ar) | 2022-06-05 |
Family
ID=60629568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SA520412155A SA520412155B1 (ar) | 2017-12-08 | 2020-06-08 | مشتقات إيميدازوبيريدين واستخدامها كدواء |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US10849907B2 (ar) |
| EP (1) | EP3720855B1 (ar) |
| JP (1) | JP6941235B2 (ar) |
| KR (1) | KR20200097301A (ar) |
| CN (1) | CN111344291B (ar) |
| AR (1) | AR113923A1 (ar) |
| AU (1) | AU2018379438B2 (ar) |
| BR (1) | BR112020008583A2 (ar) |
| CA (1) | CA3083331A1 (ar) |
| CL (1) | CL2020001402A1 (ar) |
| CO (1) | CO2020006648A2 (ar) |
| CY (1) | CY1124744T1 (ar) |
| DK (1) | DK3720855T3 (ar) |
| EA (1) | EA202091139A1 (ar) |
| ES (1) | ES2897050T3 (ar) |
| HR (1) | HRP20211726T1 (ar) |
| HU (1) | HUE056667T2 (ar) |
| IL (1) | IL274868B1 (ar) |
| LT (1) | LT3720855T (ar) |
| MA (1) | MA51020B1 (ar) |
| MX (1) | MX2020005869A (ar) |
| PE (1) | PE20211454A1 (ar) |
| PL (1) | PL3720855T3 (ar) |
| PT (1) | PT3720855T (ar) |
| RS (1) | RS62517B1 (ar) |
| SA (1) | SA520412155B1 (ar) |
| SG (1) | SG11202005138TA (ar) |
| SI (1) | SI3720855T1 (ar) |
| TW (1) | TWI809014B (ar) |
| UA (1) | UA126247C2 (ar) |
| WO (1) | WO2019110703A1 (ar) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3980420B1 (en) * | 2019-06-04 | 2023-04-19 | Boehringer Ingelheim International GmbH | Imidazopyrazine derivatives and the use thereof as medicament |
| JP7318015B2 (ja) | 2019-06-04 | 2023-07-31 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 特に抑うつ病性障害の処置のための、ｎｒ２ｂネガティブ調節剤としてのプリン誘導体および医薬としてのその使用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6495561B2 (en) | 1999-10-29 | 2002-12-17 | Merck & Co., Inc. | 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists |
| CZ2004233A3 (cs) | 2001-07-24 | 2004-12-15 | Richter Gedeon Vegyészeti Gyár Rt. | Nové amidové sloučeniny karboxylové kyseliny |
| WO2010088408A2 (en) | 2009-01-28 | 2010-08-05 | Emory University | Subunit selective nmda receptor antagonists for the treatment of neurological conditions |
| SG11201501392TA (en) | 2012-10-18 | 2015-05-28 | Hoffmann La Roche | Ethynyl derivatives as modulators of mglur5 receptor activity |
| CN106255679B (zh) | 2014-02-27 | 2019-09-06 | 默克专利有限公司 | 用作nav通道抑制剂的杂环化合物及其用途 |
| TW201609741A (zh) * | 2014-06-04 | 2016-03-16 | 盧郡控股（開曼）有限公司 | 作為ｎｒ２ｂ ｎｍｄａ受體拮抗劑之二氟乙基吡啶衍生物 |
| US10913736B2 (en) | 2014-08-22 | 2021-02-09 | University Of Washington | Specific inhibitors of methionyl-tRNA synthetase |
| ES2723436T3 (es) * | 2014-09-15 | 2019-08-27 | Rugen Holdings Cayman Ltd | Derivados de pirrolopirimidina como antagonistas del receptor NMDA NR2B |
-
2018
- 2018-12-06 HU HUE18826510A patent/HUE056667T2/hu unknown
- 2018-12-06 JP JP2020530609A patent/JP6941235B2/ja active Active
- 2018-12-06 DK DK18826510.2T patent/DK3720855T3/da active
- 2018-12-06 MX MX2020005869A patent/MX2020005869A/es unknown
- 2018-12-06 UA UAA202003988A patent/UA126247C2/uk unknown
- 2018-12-06 CN CN201880072962.4A patent/CN111344291B/zh active Active
- 2018-12-06 WO PCT/EP2018/083728 patent/WO2019110703A1/en unknown
- 2018-12-06 LT LTEPPCT/EP2018/083728T patent/LT3720855T/lt unknown
- 2018-12-06 US US16/211,355 patent/US10849907B2/en active Active
- 2018-12-06 RS RS20211347A patent/RS62517B1/sr unknown
- 2018-12-06 MA MA51020A patent/MA51020B1/fr unknown
- 2018-12-06 AU AU2018379438A patent/AU2018379438B2/en active Active
- 2018-12-06 EP EP18826510.2A patent/EP3720855B1/en active Active
- 2018-12-06 PT PT188265102T patent/PT3720855T/pt unknown
- 2018-12-06 HR HRP20211726TT patent/HRP20211726T1/hr unknown
- 2018-12-06 CA CA3083331A patent/CA3083331A1/en active Pending
- 2018-12-06 PE PE2020000681A patent/PE20211454A1/es unknown
- 2018-12-06 KR KR1020207019541A patent/KR20200097301A/ko not_active Application Discontinuation
- 2018-12-06 SG SG11202005138TA patent/SG11202005138TA/en unknown
- 2018-12-06 ES ES18826510T patent/ES2897050T3/es active Active
- 2018-12-06 EA EA202091139A patent/EA202091139A1/ru unknown
- 2018-12-06 SI SI201830440T patent/SI3720855T1/sl unknown
- 2018-12-06 PL PL18826510T patent/PL3720855T3/pl unknown
- 2018-12-06 IL IL274868A patent/IL274868B1/en unknown
- 2018-12-06 BR BR112020008583-9A patent/BR112020008583A2/pt unknown
- 2018-12-07 TW TW107144026A patent/TWI809014B/zh active
- 2018-12-07 AR ARP180103599A patent/AR113923A1/es unknown
-
2020
- 2020-05-27 CL CL2020001402A patent/CL2020001402A1/es unknown
- 2020-05-29 CO CONC2020/0006648A patent/CO2020006648A2/es unknown
- 2020-06-08 SA SA520412155A patent/SA520412155B1/ar unknown
-
2021
- 2021-11-16 CY CY20211100993T patent/CY1124744T1/el unknown
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