DK3720855T3 - Imidazopyridinderivater og avendelsen deraf som medikament - Google Patents

Imidazopyridinderivater og avendelsen deraf som medikament Download PDF

Info

Publication number
DK3720855T3
DK3720855T3 DK18826510.2T DK18826510T DK3720855T3 DK 3720855 T3 DK3720855 T3 DK 3720855T3 DK 18826510 T DK18826510 T DK 18826510T DK 3720855 T3 DK3720855 T3 DK 3720855T3
Authority
DK
Denmark
Prior art keywords
medicines
imidazopyridine derivatives
imidazopyridine
derivatives
Prior art date
Application number
DK18826510.2T
Other languages
English (en)
Inventor
Riccardo Giovannini
Angelo Ceci
Georg Dahmann
Cornelia Dorner-Ciossek
Lothar Kussmaul
Roland Pfau
Dieter Wiedenmayer
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of DK3720855T3 publication Critical patent/DK3720855T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pyrrole Compounds (AREA)
DK18826510.2T 2017-12-08 2018-12-06 Imidazopyridinderivater og avendelsen deraf som medikament DK3720855T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17206152 2017-12-08
PCT/EP2018/083728 WO2019110703A1 (en) 2017-12-08 2018-12-06 Imidazopyridine derivatives and the use thereof as medicament

Publications (1)

Publication Number Publication Date
DK3720855T3 true DK3720855T3 (da) 2021-11-08

Family

ID=60629568

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18826510.2T DK3720855T3 (da) 2017-12-08 2018-12-06 Imidazopyridinderivater og avendelsen deraf som medikament

Country Status (31)

Country Link
US (1) US10849907B2 (da)
EP (1) EP3720855B1 (da)
JP (1) JP6941235B2 (da)
KR (1) KR20200097301A (da)
CN (1) CN111344291B (da)
AR (1) AR113923A1 (da)
AU (1) AU2018379438B2 (da)
BR (1) BR112020008583A2 (da)
CA (1) CA3083331A1 (da)
CL (1) CL2020001402A1 (da)
CO (1) CO2020006648A2 (da)
CY (1) CY1124744T1 (da)
DK (1) DK3720855T3 (da)
EA (1) EA202091139A1 (da)
ES (1) ES2897050T3 (da)
HR (1) HRP20211726T1 (da)
HU (1) HUE056667T2 (da)
IL (1) IL274868B2 (da)
LT (1) LT3720855T (da)
MA (1) MA51020B1 (da)
MX (1) MX2020005869A (da)
PE (1) PE20211454A1 (da)
PL (1) PL3720855T3 (da)
PT (1) PT3720855T (da)
RS (1) RS62517B1 (da)
SA (1) SA520412155B1 (da)
SG (1) SG11202005138TA (da)
SI (1) SI3720855T1 (da)
TW (1) TWI809014B (da)
UA (1) UA126247C2 (da)
WO (1) WO2019110703A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113950478B (zh) * 2019-06-04 2024-02-02 勃林格殷格翰国际有限公司 作为nr2b负向调节剂的嘌呤衍生物及其作为药物的用途,特别是用于治疗抑郁病症
CN113906033B (zh) * 2019-06-04 2024-04-02 勃林格殷格翰国际有限公司 咪唑并吡嗪衍生物及其作为药剂的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495561B2 (en) * 1999-10-29 2002-12-17 Merck & Co., Inc. 2-cyclohexyl imidazopyridine NMDA/NR2B antagonists
NZ530055A (en) 2001-07-24 2005-07-29 Richter Gedeon Vegyeszet Piperidine derivatives as NMDA receptor antagonists
US8822462B2 (en) 2009-01-28 2014-09-02 Emory University Subunit selective NMDA receptor potentiators for the treatment of neurological conditions
NZ705144A (en) 2012-10-18 2018-09-28 Hoffmann La Roche Ethynyl derivatives as modulators of mglur5 receptor activity
AU2015223049B2 (en) 2014-02-27 2019-03-21 Merck Patent Gmbh Heterocyclic compounds as NaV channel inhibitors and uses thereof
EP3152213B1 (en) * 2014-06-04 2018-10-31 Rugen Holdings (Cayman) Limited Difluoroethylpyridine derivatives as nr2b nmda receptor antagonists
WO2016029146A1 (en) * 2014-08-22 2016-02-25 University Of Washington Specific inhibitors of methionyl-trna synthetase
ES2723436T3 (es) * 2014-09-15 2019-08-27 Rugen Holdings Cayman Ltd Derivados de pirrolopirimidina como antagonistas del receptor NMDA NR2B

Also Published As

Publication number Publication date
EP3720855A1 (en) 2020-10-14
MX2020005869A (es) 2020-09-09
SA520412155B1 (ar) 2022-06-05
IL274868B1 (en) 2024-02-01
IL274868A (en) 2020-07-30
EA202091139A1 (ru) 2020-11-23
CY1124744T1 (el) 2022-07-22
MA51020A (fr) 2021-05-26
SG11202005138TA (en) 2020-06-29
UA126247C2 (uk) 2022-09-07
HUE056667T2 (hu) 2022-02-28
CO2020006648A2 (es) 2020-06-09
ES2897050T3 (es) 2022-02-28
US10849907B2 (en) 2020-12-01
AU2018379438A1 (en) 2020-05-07
AR113923A1 (es) 2020-07-01
SI3720855T1 (sl) 2021-12-31
PE20211454A1 (es) 2021-08-05
EP3720855B1 (en) 2021-08-25
TW201936198A (zh) 2019-09-16
IL274868B2 (en) 2024-06-01
US20190175605A1 (en) 2019-06-13
MA51020B1 (fr) 2021-10-29
JP6941235B2 (ja) 2021-09-29
RS62517B1 (sr) 2021-11-30
CA3083331A1 (en) 2019-06-13
WO2019110703A1 (en) 2019-06-13
AU2018379438B2 (en) 2022-08-18
JP2021505584A (ja) 2021-02-18
BR112020008583A2 (pt) 2020-10-20
CN111344291B (zh) 2023-05-05
CL2020001402A1 (es) 2020-09-21
KR20200097301A (ko) 2020-08-18
TWI809014B (zh) 2023-07-21
LT3720855T (lt) 2021-11-10
PL3720855T3 (pl) 2022-01-24
PT3720855T (pt) 2021-11-03
HRP20211726T1 (hr) 2022-02-18
CN111344291A (zh) 2020-06-26

Similar Documents

Publication Publication Date Title
DK3452463T3 (da) Amidsubstituerede pyridinyltriazolderivater og anvendelser deraf
DK3149001T3 (da) Hidtil ukendte pyrazolopyrimidinderivater og deres anvendelse som MALT1-hæmmere
DK3478693T3 (da) Boronsyrederivater og terapeutiske anvendelser deraf
DK3490565T3 (da) Azetidinderivater som chemokinreceptormodulatorer og anvendelser deraf
DK3328849T5 (da) 1,1,1-trifluor-3-hydroxypropan-2-yl-carbamat-derivater og 1,1,1-trifluor-4-hydroxybutan-2-yl-carbamat-derivater som magl-inhibitorer
DK3307707T3 (da) Halogensubstituerede phenoxyphenylamidiner og anvendelsen deraf som fungicider
DK3786160T3 (da) Pyridinderivater og terapeutiske anvendelser deraf som trpc6-inhibitorer
DK3233863T3 (da) Kondenserede ringheteroarylforbindelser og anvendelse deraf som trk-hæmmere
DK3210977T3 (da) Hidtil ukendt aminoalkylbenzothiazepinderivat og anvendelse deraf
DK3357513T3 (da) Farmaceutisk sammensætning og anvendelse deraf
DK3412660T3 (da) Sulfonamidderivat og farmaceutisk sammensætning indeholdende samme
DK3634377T3 (da) Farmaceutisk formulering
DK3347353T3 (da) Pyrazolyl-substituerede heteroaryler og deres anvendelse som lægemidler
DK3514153T3 (da) Pyrimidinforbindelse og farmaceutisk anvendelse deraf
DK3409660T3 (da) Cyklisk aminderivat og farmaceutisk anvendelse deraf
DK3347356T3 (da) Tricyclic forbundet pyridin-2-one-derivater og deres anvendelse som brd4-hæmmere
DK3214079T3 (da) Seks-leddede benzodiazepinderivater som dpp-4-inhibitorer og hvordan de bruges
DK3642202T3 (da) Dihydro-pyrrolo-pyridin-derivater
DK3464260T3 (da) Forbindelser, der indeholder ureamotiver, og derivater deraf som antibakterielle lægemidler
DK3204085T3 (da) Hus og lægemiddeladministrationsanordning hermed
IL263969A (en) Benzodioxane derivatives and their pharmaceutical use
DK3971177T3 (da) Aminopyridin-derivater og anvendelse deraf som selektive ALK-2-inhibitorer
BR112016026552A2 (pt) derivados de carboxamida, seus usos, composição farmacêutica, e combinação
DK3386956T3 (da) Fumagillolderivater og polymorfer deraf
DK3277682T3 (da) 6-morpholinyl-2-pyrazolyl-9h-purinderivater og anvendelse heraf som pi3k- hæmmere