SA07280243B1 - صورة جديدة لبلورة مشتركة من 2- {إيثيل [3- ({ 4- [(5- {2- [(3- فلورو فينيل) أمينو]-2- أوكسو إيثيل}-1h- بيرازول-3- يل) أمينو] كينازولين-7- يل} أوكسي) بروبيل] أمينو} إيثيل داي هيدروجين فوسفات - Google Patents

صورة جديدة لبلورة مشتركة من 2- {إيثيل [3- ({ 4- [(5- {2- [(3- فلورو فينيل) أمينو]-2- أوكسو إيثيل}-1h- بيرازول-3- يل) أمينو] كينازولين-7- يل} أوكسي) بروبيل] أمينو} إيثيل داي هيدروجين فوسفات Download PDF

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Publication number
SA07280243B1
SA07280243B1 SA07280243A SA07280243A SA07280243B1 SA 07280243 B1 SA07280243 B1 SA 07280243B1 SA 07280243 A SA07280243 A SA 07280243A SA 07280243 A SA07280243 A SA 07280243A SA 07280243 B1 SA07280243 B1 SA 07280243B1
Authority
SA
Saudi Arabia
Prior art keywords
amino
crystal
maleate
ethyl
azd1152
Prior art date
Application number
SA07280243A
Other languages
Arabic (ar)
English (en)
Inventor
جورج جوزيف اسبندا
ريتشارد ستوري
Original Assignee
استرازينيكا ايه بي
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36637528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SA07280243(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by استرازينيكا ايه بي filed Critical استرازينيكا ايه بي
Publication of SA07280243B1 publication Critical patent/SA07280243B1/ar

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SA07280243A 2006-05-16 2007-05-14 صورة جديدة لبلورة مشتركة من 2- {إيثيل [3- ({ 4- [(5- {2- [(3- فلورو فينيل) أمينو]-2- أوكسو إيثيل}-1h- بيرازول-3- يل) أمينو] كينازولين-7- يل} أوكسي) بروبيل] أمينو} إيثيل داي هيدروجين فوسفات SA07280243B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0609621.8A GB0609621D0 (en) 2006-05-16 2006-05-16 Novel co-crystal

Publications (1)

Publication Number Publication Date
SA07280243B1 true SA07280243B1 (ar) 2010-12-01

Family

ID=36637528

Family Applications (1)

Application Number Title Priority Date Filing Date
SA07280243A SA07280243B1 (ar) 2006-05-16 2007-05-14 صورة جديدة لبلورة مشتركة من 2- {إيثيل [3- ({ 4- [(5- {2- [(3- فلورو فينيل) أمينو]-2- أوكسو إيثيل}-1h- بيرازول-3- يل) أمينو] كينازولين-7- يل} أوكسي) بروبيل] أمينو} إيثيل داي هيدروجين فوسفات

Country Status (22)

Country Link
US (1) US7625910B2 (enExample)
EP (1) EP2027114A1 (enExample)
JP (1) JP2009537498A (enExample)
KR (1) KR20090009297A (enExample)
CN (1) CN101448823A (enExample)
AR (1) AR060963A1 (enExample)
AU (1) AU2007251304A1 (enExample)
BR (1) BRPI0712791A2 (enExample)
CA (1) CA2650519A1 (enExample)
CL (1) CL2007001388A1 (enExample)
EC (1) ECSP088890A (enExample)
GB (1) GB0609621D0 (enExample)
IL (1) IL194862A0 (enExample)
MX (1) MX2008014550A (enExample)
NO (1) NO20084580L (enExample)
RU (1) RU2008149242A (enExample)
SA (1) SA07280243B1 (enExample)
TW (1) TW200813026A (enExample)
UA (1) UA95108C2 (enExample)
UY (1) UY30351A1 (enExample)
WO (1) WO2007132227A1 (enExample)
ZA (1) ZA200809172B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE446093T1 (de) * 2001-12-24 2009-11-15 Astrazeneca Ab Substituierte chinazolin-derivate als aurora- kinase inhibitoren
CA2526285A1 (en) * 2003-05-15 2004-12-23 Arqule, Inc. Inhibitors of p38 and methods of using the same
CA2584368A1 (en) * 2004-10-19 2006-04-27 Arqule, Inc. Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 map kinase
WO2007123892A2 (en) * 2006-04-17 2007-11-01 Arqule Inc. Raf inhibitors and their uses
CA2744713A1 (en) * 2008-12-05 2010-06-10 Arqule, Inc. Raf inhibitors and their uses
NZ598758A (en) * 2009-09-11 2013-12-20 Amgen Inc N-4 (-((3-(2-amino-4 pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine for use in the treatment of antimitotic agent resistant cancer
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
GB201020179D0 (en) 2010-11-29 2011-01-12 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201209609D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201307577D0 (en) 2013-04-26 2013-06-12 Astex Therapeutics Ltd New compounds
HUE034490T2 (en) 2013-09-16 2018-02-28 Astrazeneca Ab Therapeutic polymer nanoparticles and methods for their preparation and use
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
BR112016022056B1 (pt) 2014-03-26 2023-04-11 Astex Therapeutics Limited Combinação, composição farmacêutica, uso de uma combinação ou uma composição farmacêutica, e, produto farmacêutico
US10736900B2 (en) 2014-03-26 2020-08-11 Astex Therapeutics Ltd Combinations of an FGFR inhibitor and an IGF1R inhibitor
TWI719960B (zh) 2015-02-10 2021-03-01 英商阿斯迪克治療公司 新穎組成物
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
HUE050567T2 (hu) 2015-09-23 2020-12-28 Janssen Pharmaceutica Nv Triciklusos heterociklusok rák kezelésére
WO2017050865A1 (en) 2015-09-23 2017-03-30 Janssen Pharmaceutica Nv Bi-heteroaryl substituted 1,4-benzodiazepines and uses thereof for the treatment of cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE446093T1 (de) * 2001-12-24 2009-11-15 Astrazeneca Ab Substituierte chinazolin-derivate als aurora- kinase inhibitoren
UA83814C2 (ru) * 2002-12-24 2008-08-26 Астразенека Аб Производные фосфонооксихиназолина и их фармацевтическое применение

Also Published As

Publication number Publication date
US20080045481A1 (en) 2008-02-21
NO20084580L (no) 2009-02-05
UY30351A1 (es) 2008-01-02
GB0609621D0 (en) 2006-06-21
CA2650519A1 (en) 2007-11-22
ZA200809172B (en) 2009-12-30
KR20090009297A (ko) 2009-01-22
UA95108C2 (en) 2011-07-11
JP2009537498A (ja) 2009-10-29
IL194862A0 (en) 2009-08-03
US7625910B2 (en) 2009-12-01
BRPI0712791A2 (pt) 2012-09-04
WO2007132227A1 (en) 2007-11-22
CN101448823A (zh) 2009-06-03
MX2008014550A (es) 2008-11-27
EP2027114A1 (en) 2009-02-25
AR060963A1 (es) 2008-07-23
RU2008149242A (ru) 2010-06-27
AU2007251304A1 (en) 2007-11-22
CL2007001388A1 (es) 2008-01-18
ECSP088890A (es) 2008-12-30
TW200813026A (en) 2008-03-16

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