UY30351A1 - Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones - Google Patents

Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones

Info

Publication number
UY30351A1
UY30351A1 UY30351A UY30351A UY30351A1 UY 30351 A1 UY30351 A1 UY 30351A1 UY 30351 A UY30351 A UY 30351A UY 30351 A UY30351 A UY 30351A UY 30351 A1 UY30351 A1 UY 30351A1
Authority
UY
Uruguay
Prior art keywords
amino
quinazolin
fluorophenyl
dihydrogen phosphate
oxoetil
Prior art date
Application number
UY30351A
Other languages
English (en)
Spanish (es)
Inventor
George Joseph Sependa
Richard Storey
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36637528&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY30351(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY30351A1 publication Critical patent/UY30351A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UY30351A 2006-05-16 2007-05-15 Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones UY30351A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0609621.8A GB0609621D0 (en) 2006-05-16 2006-05-16 Novel co-crystal

Publications (1)

Publication Number Publication Date
UY30351A1 true UY30351A1 (es) 2008-01-02

Family

ID=36637528

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30351A UY30351A1 (es) 2006-05-16 2007-05-15 Cocristal maleato de 2-{etil[3-((4-((5-(2-3-fluorofenil)amino]-2-oxoetil}-1h-pirazol-3-il)amino)quinazolin-7-il)oxi)propil)amino]etil dihidrogeno fosfato, procesos de preparacion, composiciones y aplicaciones

Country Status (22)

Country Link
US (1) US7625910B2 (enExample)
EP (1) EP2027114A1 (enExample)
JP (1) JP2009537498A (enExample)
KR (1) KR20090009297A (enExample)
CN (1) CN101448823A (enExample)
AR (1) AR060963A1 (enExample)
AU (1) AU2007251304A1 (enExample)
BR (1) BRPI0712791A2 (enExample)
CA (1) CA2650519A1 (enExample)
CL (1) CL2007001388A1 (enExample)
EC (1) ECSP088890A (enExample)
GB (1) GB0609621D0 (enExample)
IL (1) IL194862A0 (enExample)
MX (1) MX2008014550A (enExample)
NO (1) NO20084580L (enExample)
RU (1) RU2008149242A (enExample)
SA (1) SA07280243B1 (enExample)
TW (1) TW200813026A (enExample)
UA (1) UA95108C2 (enExample)
UY (1) UY30351A1 (enExample)
WO (1) WO2007132227A1 (enExample)
ZA (1) ZA200809172B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4498741B2 (ja) * 2001-12-24 2010-07-07 アストラゼネカ アクチボラグ オーロラキナーゼ阻害剤としての置換キナゾリン誘導体
ATE534649T1 (de) * 2003-05-15 2011-12-15 Arqule Inc Imidazothiazole und imidazoxazolderivative als inhibitoren von p38
CA2584368A1 (en) * 2004-10-19 2006-04-27 Arqule, Inc. Synthesis of imidazooxazole and imidazothiazole inhibitors of p38 map kinase
US7501430B2 (en) * 2006-04-17 2009-03-10 Arqule, Inc. RAF inhibitors and their uses
CA2744713A1 (en) * 2008-12-05 2010-06-10 Arqule, Inc. Raf inhibitors and their uses
EP2818170B1 (en) * 2009-09-11 2018-12-05 Amgen, Inc N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridin yl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine for use in the treatment of antimitotic agent resistant cancer
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
GB201020179D0 (en) 2010-11-29 2011-01-12 Astex Therapeutics Ltd New compounds
GB201118675D0 (en) 2011-10-28 2011-12-14 Astex Therapeutics Ltd New compounds
GB201118656D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118654D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201118652D0 (en) 2011-10-28 2011-12-07 Astex Therapeutics Ltd New compounds
GB201209609D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
GB201307577D0 (en) 2013-04-26 2013-06-12 Astex Therapeutics Ltd New compounds
JP6543258B2 (ja) 2013-09-16 2019-07-10 アストラゼネカ アクチボラグ 治療用重合性ナノ粒子とそれを作製して使用する方法
JO3512B1 (ar) 2014-03-26 2020-07-05 Astex Therapeutics Ltd مشتقات كينوكسالين مفيدة كمعدلات لإنزيم fgfr كيناز
BR112016022062B1 (pt) 2014-03-26 2023-04-11 Astex Therapeutics Limited Combinação, composição farmacêutica, uso de uma combinação ou de uma composição farmacêutica, e, produto farmacêutico
PL3122358T3 (pl) 2014-03-26 2021-06-14 Astex Therapeutics Ltd. Połączenia inhibitorów fgfr i cmet w leczeniu nowotworu
JOP20200201A1 (ar) 2015-02-10 2017-06-16 Astex Therapeutics Ltd تركيبات صيدلانية تشتمل على n-(3.5- ثنائي ميثوكسي فينيل)-n'-(1-ميثيل إيثيل)-n-[3-(ميثيل-1h-بيرازول-4-يل) كينوكسالين-6-يل]إيثان-1.2-ثنائي الأمين
US10478494B2 (en) 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
HRP20220012T1 (hr) 2015-09-23 2022-04-01 Janssen Pharmaceutica Nv Bi-heteroaril supstituirani 1,4-benzodiazepini i njihova upotreba za liječenje raka
BR112018005637B1 (pt) 2015-09-23 2023-11-28 Janssen Pharmaceutica Nv Compostos derivados de quinoxalina, quinolina e quinazolinona,composições farmacêuticas que os compreende, e uso dos referidos compostos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4498741B2 (ja) * 2001-12-24 2010-07-07 アストラゼネカ アクチボラグ オーロラキナーゼ阻害剤としての置換キナゾリン誘導体
BRPI0317717B8 (pt) * 2002-12-24 2021-05-25 Astrazeneca Ab composto, composição farmacêutica, e uso de um composto

Also Published As

Publication number Publication date
IL194862A0 (en) 2009-08-03
CN101448823A (zh) 2009-06-03
GB0609621D0 (en) 2006-06-21
AU2007251304A1 (en) 2007-11-22
AR060963A1 (es) 2008-07-23
RU2008149242A (ru) 2010-06-27
SA07280243B1 (ar) 2010-12-01
TW200813026A (en) 2008-03-16
US7625910B2 (en) 2009-12-01
JP2009537498A (ja) 2009-10-29
CL2007001388A1 (es) 2008-01-18
BRPI0712791A2 (pt) 2012-09-04
CA2650519A1 (en) 2007-11-22
MX2008014550A (es) 2008-11-27
EP2027114A1 (en) 2009-02-25
UA95108C2 (en) 2011-07-11
ECSP088890A (es) 2008-12-30
KR20090009297A (ko) 2009-01-22
WO2007132227A1 (en) 2007-11-22
NO20084580L (no) 2009-02-05
ZA200809172B (en) 2009-12-30
US20080045481A1 (en) 2008-02-21

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Effective date: 20120606