RU97108978A - Антитела против аллогенных и ксеногенных белков, их применение в диагностике и терапии и способы их определения - Google Patents
Антитела против аллогенных и ксеногенных белков, их применение в диагностике и терапии и способы их определенияInfo
- Publication number
- RU97108978A RU97108978A RU97108978/14A RU97108978A RU97108978A RU 97108978 A RU97108978 A RU 97108978A RU 97108978/14 A RU97108978/14 A RU 97108978/14A RU 97108978 A RU97108978 A RU 97108978A RU 97108978 A RU97108978 A RU 97108978A
- Authority
- RU
- Russia
- Prior art keywords
- proteins
- allogenous
- diagnostics
- therapy
- access numbers
- Prior art date
Links
- 108090001123 antibodies Proteins 0.000 title claims 6
- 102000004965 antibodies Human genes 0.000 title claims 6
- 102000004169 proteins and genes Human genes 0.000 title claims 5
- 108090000623 proteins and genes Proteins 0.000 title claims 5
- 238000007374 clinical diagnostic method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 210000004408 Hybridomas Anatomy 0.000 claims 3
- 229960000070 antineoplastic Monoclonal antibodies Drugs 0.000 claims 3
- 229960000060 monoclonal antibodies Drugs 0.000 claims 3
- 108010045030 monoclonal antibodies Proteins 0.000 claims 3
- 102000005614 monoclonal antibodies Human genes 0.000 claims 3
- 108010047814 Antigen-Antibody Complex Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N Perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 claims 2
- 210000000056 organs Anatomy 0.000 claims 2
- 241000283707 Capra Species 0.000 claims 1
- 241000282412 Homo Species 0.000 claims 1
- 210000004185 Liver Anatomy 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 230000001472 cytotoxic Effects 0.000 claims 1
- 231100000433 cytotoxic Toxicity 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000000521 hyperimmunizing Effects 0.000 claims 1
- 230000001900 immune effect Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Claims (4)
1. Способ иммунологического обнаружения природных антител, узнающих белок, экстрагируемый из органов млекопитающих, узнаваемый моноклональными антителами, секретируемыми гибридомами, депонированными в ЕСАСС под номерами доступа 930806103 или 930806104, и присутствующий приблизительно в 93% твердых опухолей человека, заключающийся в обнаружении иммунного комплекса между указанными природными антителами и необязательно мечеными указанными белками.
2. Способ по п. 1, в котором иммунный комплекс обнаруживают при помощи второго меченого антитела против вида.
3. Природные антитела, узнающие белки, экстрагируемые из органов млекопитающих, узнаваемые моноклональными антителами, секретируемыми гибридомами, депонированными в ЕСАСС под номерами доступа 930806103 или 930806104, и присутствующие приблизительно в 93% твердых опухолей человека.
4. Цитотоксические композиции, содержащие эффективное количество антител или гипериммунные сыворотки, индуцированные иммунизацией животных или людей белками, экстрагируемыми из печени козы перхлорной кислотой и узнаваемыми моноклональными антителами, секретируемыми гибридомами, депонированными в ЕСАСС под номерами доступа 930806103 или 930806104.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI94A002238 | 1994-11-04 | ||
| IT94MI002238A IT1276860B1 (it) | 1994-11-04 | 1994-11-04 | Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU97108978A true RU97108978A (ru) | 1999-05-27 |
| RU2160445C2 RU2160445C2 (ru) | 2000-12-10 |
Family
ID=11369803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU97108978/14A RU2160445C2 (ru) | 1994-11-04 | 1995-10-30 | Антитела против аллогенных и ксеногенных белков, их применение в диагностике и терапии и способы их определения |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0789716B1 (ru) |
| JP (1) | JPH10508591A (ru) |
| KR (1) | KR100426029B1 (ru) |
| CN (1) | CN1046737C (ru) |
| AR (1) | AR002243A1 (ru) |
| AT (1) | ATE192166T1 (ru) |
| AU (1) | AU690756B2 (ru) |
| BR (1) | BR9509556A (ru) |
| CA (1) | CA2204380A1 (ru) |
| CZ (1) | CZ288322B6 (ru) |
| DE (1) | DE69516534T2 (ru) |
| DK (1) | DK0789716T3 (ru) |
| ES (1) | ES2147617T3 (ru) |
| FI (1) | FI971879A (ru) |
| GR (1) | GR3033956T3 (ru) |
| HU (1) | HUT76880A (ru) |
| IL (1) | IL115862A (ru) |
| IT (1) | IT1276860B1 (ru) |
| NO (1) | NO972046D0 (ru) |
| NZ (1) | NZ295171A (ru) |
| PL (1) | PL181115B1 (ru) |
| PT (1) | PT789716E (ru) |
| RU (1) | RU2160445C2 (ru) |
| TR (1) | TR199501353A2 (ru) |
| WO (1) | WO1996014340A1 (ru) |
| ZA (1) | ZA959255B (ru) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1283634B1 (it) * | 1996-05-10 | 1998-04-23 | Zetesis Spa | Un metodo citofluorimetrico per la determinazione nel siero di anti- corpi anti-antigene tumorali |
| US20010014471A1 (en) * | 1999-04-15 | 2001-08-16 | Vytautas Naktinis | Recombinant protein and its use in therapy and diagnostics |
| IT201600127428A1 (it) * | 2016-12-16 | 2018-06-16 | Cusani Alberto Bartorelli | Nuova proteina ricombinante uk 114 in forma stabile polimerica per uso nella terapia, nella diagnostica e nella prevenzione di neoplasie maligne |
| IT201900022203A1 (it) * | 2019-11-26 | 2021-05-26 | Cusani Alberto Bartorelli | Proteine uk 114 da salmone per uso nella terapia, nella diagnostica e nella prevenzione di neoplasie maligne |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1244879B (it) * | 1990-12-11 | 1994-09-12 | Alberto Bartorelli | Estratti da tessuti animali, utili in terapia e in diagnostica. |
-
1994
- 1994-11-04 IT IT94MI002238A patent/IT1276860B1/it active IP Right Grant
-
1995
- 1995-10-30 CA CA002204380A patent/CA2204380A1/en not_active Abandoned
- 1995-10-30 WO PCT/EP1995/004239 patent/WO1996014340A1/en active IP Right Grant
- 1995-10-30 BR BR9509556A patent/BR9509556A/pt not_active Application Discontinuation
- 1995-10-30 DK DK95936566T patent/DK0789716T3/da active
- 1995-10-30 AT AT95936566T patent/ATE192166T1/de not_active IP Right Cessation
- 1995-10-30 PT PT95936566T patent/PT789716E/pt unknown
- 1995-10-30 RU RU97108978/14A patent/RU2160445C2/ru not_active IP Right Cessation
- 1995-10-30 NZ NZ295171A patent/NZ295171A/en unknown
- 1995-10-30 DE DE69516534T patent/DE69516534T2/de not_active Expired - Fee Related
- 1995-10-30 EP EP95936566A patent/EP0789716B1/en not_active Expired - Lifetime
- 1995-10-30 CZ CZ19971314A patent/CZ288322B6/cs not_active IP Right Cessation
- 1995-10-30 HU HU9701505A patent/HUT76880A/hu unknown
- 1995-10-30 PL PL95319878A patent/PL181115B1/pl not_active IP Right Cessation
- 1995-10-30 AU AU38453/95A patent/AU690756B2/en not_active Ceased
- 1995-10-30 KR KR1019970702940A patent/KR100426029B1/ko not_active IP Right Cessation
- 1995-10-30 JP JP8515018A patent/JPH10508591A/ja not_active Ceased
- 1995-10-30 CN CN95195990A patent/CN1046737C/zh not_active Expired - Fee Related
- 1995-10-30 ES ES95936566T patent/ES2147617T3/es not_active Expired - Lifetime
- 1995-11-02 IL IL11586295A patent/IL115862A/en active IP Right Grant
- 1995-11-02 AR ARP950100034A patent/AR002243A1/es unknown
- 1995-11-02 ZA ZA959255A patent/ZA959255B/xx unknown
- 1995-11-02 TR TR95/01353A patent/TR199501353A2/xx unknown
-
1997
- 1997-05-02 NO NO972046A patent/NO972046D0/no not_active Application Discontinuation
- 1997-05-02 FI FI971879A patent/FI971879A/fi unknown
-
2000
- 2000-07-14 GR GR20000401641T patent/GR3033956T3/el not_active IP Right Cessation
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