IT1276860B1 - Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione - Google Patents

Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione

Info

Publication number
IT1276860B1
IT1276860B1 IT94MI002238A ITMI942238A IT1276860B1 IT 1276860 B1 IT1276860 B1 IT 1276860B1 IT 94MI002238 A IT94MI002238 A IT 94MI002238A IT MI942238 A ITMI942238 A IT MI942238A IT 1276860 B1 IT1276860 B1 IT 1276860B1
Authority
IT
Italy
Prior art keywords
determination
methods
antibodies against
natural antibodies
xenogenic proteins
Prior art date
Application number
IT94MI002238A
Other languages
English (en)
Inventor
Alberto Bartorelli
Original Assignee
Zetesis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zetesis Spa filed Critical Zetesis Spa
Publication of ITMI942238A0 publication Critical patent/ITMI942238A0/it
Priority to IT94MI002238A priority Critical patent/IT1276860B1/it
Priority to AT95936566T priority patent/ATE192166T1/de
Priority to DK95936566T priority patent/DK0789716T3/da
Priority to EP95936566A priority patent/EP0789716B1/en
Priority to DE69516534T priority patent/DE69516534T2/de
Priority to KR1019970702940A priority patent/KR100426029B1/ko
Priority to PT95936566T priority patent/PT789716E/pt
Priority to ES95936566T priority patent/ES2147617T3/es
Priority to BR9509556A priority patent/BR9509556A/pt
Priority to PL95319878A priority patent/PL181115B1/pl
Priority to JP8515018A priority patent/JPH10508591A/ja
Priority to PCT/EP1995/004239 priority patent/WO1996014340A1/en
Priority to AU38453/95A priority patent/AU690756B2/en
Priority to NZ295171A priority patent/NZ295171A/en
Priority to HU9701505A priority patent/HUT76880A/hu
Priority to CA002204380A priority patent/CA2204380A1/en
Priority to CZ19971314A priority patent/CZ288322B6/cs
Priority to RU97108978/14A priority patent/RU2160445C2/ru
Priority to CN95195990A priority patent/CN1046737C/zh
Priority to ZA959255A priority patent/ZA959255B/xx
Priority to TR95/01353A priority patent/TR199501353A2/xx
Priority to ARP950100034A priority patent/AR002243A1/es
Priority to IL11586295A priority patent/IL115862A/en
Publication of ITMI942238A1 publication Critical patent/ITMI942238A1/it
Priority to MXPA/A/1997/003191A priority patent/MXPA97003191A/xx
Priority to NO972046A priority patent/NO972046D0/no
Priority to FI971879A priority patent/FI971879A/fi
Application granted granted Critical
Publication of IT1276860B1 publication Critical patent/IT1276860B1/it
Priority to GR20000401641T priority patent/GR3033956T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT94MI002238A 1994-11-04 1994-11-04 Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione IT1276860B1 (it)

Priority Applications (27)

Application Number Priority Date Filing Date Title
IT94MI002238A IT1276860B1 (it) 1994-11-04 1994-11-04 Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione
HU9701505A HUT76880A (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof
CZ19971314A CZ288322B6 (en) 1994-11-04 1995-10-30 Immuno-detection method of natural antibodies
CA002204380A CA2204380A1 (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof
DE69516534T DE69516534T2 (de) 1994-11-04 1995-10-30 Antikörper gegen allogene und xenogene proteine, ihre verwendung in diagnose und therapie und verfahren zu ihrer bestimmung
DK95936566T DK0789716T3 (da) 1994-11-04 1995-10-30 Antistoffer mod allogene og xenogene proteiner, deres anvendelse ved diagnose og terapi og fremgangsmåder til bestemmelse h
PT95936566T PT789716E (pt) 1994-11-04 1995-10-30 Anticorpos contra proteinas alogenicas e xenogenicas sua utilizacao no diagnostico e na terapia e metodos para a sua determinacao
ES95936566T ES2147617T3 (es) 1994-11-04 1995-10-30 Anticuerpos contra proteinas alogenas y xenogenas, su uso en diagnostico y terapia y procedimientos para su determinacion.
BR9509556A BR9509556A (pt) 1994-11-04 1995-10-30 Anticorpos contra as proteínas alogênicas e xenogênicas seu uso em diagnóstico e terapia e processo para a determinação dos mesmos
PL95319878A PL181115B1 (pl) 1994-11-04 1995-10-30 Sposób immunologicznego wykrywania przeciwciał naturalnych, przeciwciała naturalne i preparaty cytotoksyczne
JP8515018A JPH10508591A (ja) 1994-11-04 1995-10-30 同種タンパク質および異種タンパク質に対する抗体、診断および治療におけるそれらの用途ならびにそれらを測定する方法
PCT/EP1995/004239 WO1996014340A1 (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof
RU97108978/14A RU2160445C2 (ru) 1994-11-04 1995-10-30 Антитела против аллогенных и ксеногенных белков, их применение в диагностике и терапии и способы их определения
NZ295171A NZ295171A (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins and their use in diagnosis
AT95936566T ATE192166T1 (de) 1994-11-04 1995-10-30 Antikörper gegen allogene und xenogene proteine, ihre verwendung in diagnose und therapie und verfahren zu ihrer bestimmung
EP95936566A EP0789716B1 (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof
KR1019970702940A KR100426029B1 (ko) 1994-11-04 1995-10-30 동종 및 이종 단백질에 대한 항체, 그 항체를 이용한 진단 및 치료방법 및 그 항체의 측정방법
AU38453/95A AU690756B2 (en) 1994-11-04 1995-10-30 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof
CN95195990A CN1046737C (zh) 1994-11-04 1995-10-30 同种异体和异基因蛋白的抗体,它们在诊断和治疗中的应用及其检测方法
ZA959255A ZA959255B (en) 1994-11-04 1995-11-02 Antibodies against allogenic and xenogenic proteins their use in diagnosis and therapy and methods for the determination thereof
TR95/01353A TR199501353A2 (tr) 1994-11-04 1995-11-02 Allojenik ve ksenojenik proteinlere karsi antikorlar, bunlarin teshis ve tedavide kullanilmasi ve bunlarin saptanmasi icin yöntemler.
ARP950100034A AR002243A1 (es) 1994-11-04 1995-11-02 Anticuerpos contra proteinas alogenicas y xenogenicas, su uso en diagnostico y terapia y metodos para la determinacion de los mismos.
IL11586295A IL115862A (en) 1994-11-04 1995-11-02 Antibodies against different proteins and gene bouquets, and methods for determining them
MXPA/A/1997/003191A MXPA97003191A (en) 1994-11-04 1997-04-30 Antibodies against allogenic and yxenogenic proteins, their use in diagnosis and therapy and methods for the determination of myths
NO972046A NO972046D0 (no) 1994-11-04 1997-05-02 Antistoff mot allogene og xenogene proteiner, deres bruk i diagnose og terapi samt fremgangsmåter for bestemmelse av slike
FI971879A FI971879A (fi) 1994-11-04 1997-05-02 Allogeenisten ja ksenogeenisten proteiinien vasta-aineet, niiden käyttö diagnoosissa ja hoidossa ja menetelmät niiden määrittämiseksi
GR20000401641T GR3033956T3 (en) 1994-11-04 2000-07-14 Antibodies against allogenic and xenogenic proteins, their use in diagnosis and therapy and methods for the determination thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT94MI002238A IT1276860B1 (it) 1994-11-04 1994-11-04 Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione

Publications (3)

Publication Number Publication Date
ITMI942238A0 ITMI942238A0 (it) 1994-11-04
ITMI942238A1 ITMI942238A1 (it) 1996-05-04
IT1276860B1 true IT1276860B1 (it) 1997-11-03

Family

ID=11369803

Family Applications (1)

Application Number Title Priority Date Filing Date
IT94MI002238A IT1276860B1 (it) 1994-11-04 1994-11-04 Anticorpi naturali contro proteine allogeniche e xenogeniche e metodi per la loro determinazione

Country Status (26)

Country Link
EP (1) EP0789716B1 (it)
JP (1) JPH10508591A (it)
KR (1) KR100426029B1 (it)
CN (1) CN1046737C (it)
AR (1) AR002243A1 (it)
AT (1) ATE192166T1 (it)
AU (1) AU690756B2 (it)
BR (1) BR9509556A (it)
CA (1) CA2204380A1 (it)
CZ (1) CZ288322B6 (it)
DE (1) DE69516534T2 (it)
DK (1) DK0789716T3 (it)
ES (1) ES2147617T3 (it)
FI (1) FI971879A (it)
GR (1) GR3033956T3 (it)
HU (1) HUT76880A (it)
IL (1) IL115862A (it)
IT (1) IT1276860B1 (it)
NO (1) NO972046D0 (it)
NZ (1) NZ295171A (it)
PL (1) PL181115B1 (it)
PT (1) PT789716E (it)
RU (1) RU2160445C2 (it)
TR (1) TR199501353A2 (it)
WO (1) WO1996014340A1 (it)
ZA (1) ZA959255B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283634B1 (it) * 1996-05-10 1998-04-23 Zetesis Spa Un metodo citofluorimetrico per la determinazione nel siero di anti- corpi anti-antigene tumorali
US20010014471A1 (en) * 1999-04-15 2001-08-16 Vytautas Naktinis Recombinant protein and its use in therapy and diagnostics
IT201600127428A1 (it) * 2016-12-16 2018-06-16 Cusani Alberto Bartorelli Nuova proteina ricombinante uk 114 in forma stabile polimerica per uso nella terapia, nella diagnostica e nella prevenzione di neoplasie maligne
IT201900022203A1 (it) * 2019-11-26 2021-05-26 Cusani Alberto Bartorelli Proteine uk 114 da salmone per uso nella terapia, nella diagnostica e nella prevenzione di neoplasie maligne

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1244879B (it) * 1990-12-11 1994-09-12 Alberto Bartorelli Estratti da tessuti animali, utili in terapia e in diagnostica.

Also Published As

Publication number Publication date
DE69516534T2 (de) 2000-11-30
ITMI942238A1 (it) 1996-05-04
PT789716E (pt) 2000-09-29
CN1166838A (zh) 1997-12-03
EP0789716A1 (en) 1997-08-20
WO1996014340A1 (en) 1996-05-17
KR100426029B1 (ko) 2004-07-31
KR970707161A (ko) 1997-12-01
FI971879A0 (fi) 1997-05-02
RU2160445C2 (ru) 2000-12-10
ATE192166T1 (de) 2000-05-15
ITMI942238A0 (it) 1994-11-04
PL181115B1 (pl) 2001-05-31
CA2204380A1 (en) 1996-05-17
HUT76880A (en) 1997-12-29
TR199501353A2 (tr) 1996-06-21
AR002243A1 (es) 1998-03-11
CZ288322B6 (en) 2001-05-16
IL115862A (en) 2001-06-14
CN1046737C (zh) 1999-11-24
NO972046L (no) 1997-05-02
JPH10508591A (ja) 1998-08-25
ES2147617T3 (es) 2000-09-16
ZA959255B (en) 1996-05-29
IL115862A0 (en) 1996-01-31
BR9509556A (pt) 1997-09-16
NO972046D0 (no) 1997-05-02
PL319878A1 (en) 1997-09-01
AU3845395A (en) 1996-05-31
MX9703191A (es) 1997-07-31
DK0789716T3 (da) 2000-10-09
AU690756B2 (en) 1998-04-30
FI971879A (fi) 1997-06-24
CZ131497A3 (en) 1997-12-17
EP0789716B1 (en) 2000-04-26
GR3033956T3 (en) 2000-11-30
NZ295171A (en) 1998-07-28
DE69516534D1 (de) 2000-05-31

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971126