RU93004457A - 1-карба-(1-детиа)-цефемы и промежуточные продукты для их получения - Google Patents

1-карба-(1-детиа)-цефемы и промежуточные продукты для их получения

Info

Publication number
RU93004457A
RU93004457A RU93004457/33A RU93004457A RU93004457A RU 93004457 A RU93004457 A RU 93004457A RU 93004457/33 A RU93004457/33 A RU 93004457/33A RU 93004457 A RU93004457 A RU 93004457A RU 93004457 A RU93004457 A RU 93004457A
Authority
RU
Russia
Prior art keywords
cefits
carbes
detia
production
intermediate products
Prior art date
Application number
RU93004457/33A
Other languages
English (en)
Other versions
RU2107067C1 (ru
Inventor
Джон Тернански Роберт
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/643,244 external-priority patent/US5077287A/en
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of RU93004457A publication Critical patent/RU93004457A/ru
Application granted granted Critical
Publication of RU2107067C1 publication Critical patent/RU2107067C1/ru

Links

Claims (1)

  1. Представляются различные 3-замещенные 1-карба-(1-детиа)-3-цефемы, полезные в качестве антибактериальных средств. Предусматриваются также фармацевтические композиции, содержащие эти соединения, и методы лечения бактериальных инфекций у человека и других животных.
RU93004457A 1991-01-18 1993-01-22 Производные 1-карба-(1-детиа)-цефема RU2107067C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/643,244 US5077287A (en) 1991-01-18 1991-01-18 3-thiazolylthio carbacephem antibacterial agents
US643244 1991-01-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
RU5010519 Division 1992-01-03

Publications (2)

Publication Number Publication Date
RU93004457A true RU93004457A (ru) 1995-06-19
RU2107067C1 RU2107067C1 (ru) 1998-03-20

Family

ID=24579974

Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004457A RU2107067C1 (ru) 1991-01-18 1993-01-22 Производные 1-карба-(1-детиа)-цефема

Country Status (21)

Country Link
US (1) US5077287A (ru)
EP (1) EP0495585A1 (ru)
JP (1) JPH04321686A (ru)
KR (1) KR920014810A (ru)
CN (1) CN1063284A (ru)
AU (1) AU642334B2 (ru)
BR (1) BR9200058A (ru)
CA (1) CA2058592C (ru)
CZ (1) CZ281909B6 (ru)
FI (1) FI920110A (ru)
HU (1) HUT60268A (ru)
IE (1) IE920084A1 (ru)
IL (1) IL100575A (ru)
MX (1) MX9200105A (ru)
MY (1) MY131300A (ru)
NO (1) NO301328B1 (ru)
NZ (1) NZ241250A (ru)
PT (1) PT99984B (ru)
RU (1) RU2107067C1 (ru)
YU (1) YU2392A (ru)
ZA (1) ZA9225B (ru)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5179088A (en) * 1990-02-12 1993-01-12 Eli Lilly And Company 1-carba(dethia)cephalosporin antibiotics
US5272265A (en) * 1990-02-12 1993-12-21 Eli Lilly And Company 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems
IL100576A (en) * 1991-01-18 1995-11-27 Eli Lilley And Company Cephalosporin antibiotics
JP3238209B2 (ja) * 1992-09-30 2001-12-10 塩野義製薬株式会社 チオメチルチオカルバセファロスポリン誘導体
US5525599A (en) * 1993-07-21 1996-06-11 Eli Lilly And Company 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids
DE4333697A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
WO1995026966A1 (en) * 1994-04-01 1995-10-12 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
US5565445A (en) * 1995-02-22 1996-10-15 Merck & Co., Inc. 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use
WO1996038450A1 (en) * 1995-05-31 1996-12-05 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
AU7126198A (en) * 1997-04-17 1998-11-11 Microcide Pharmaceuticals, Inc. Improved beta-lactam antibiotics
US6025352A (en) * 1997-09-29 2000-02-15 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6030965A (en) * 1997-09-30 2000-02-29 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
CA2526875A1 (en) * 2003-04-30 2004-11-18 Trine Pharmaceuticals, Inc. Carbacephem beta-lactam antibiotics
US20080146535A1 (en) * 2003-04-30 2008-06-19 Tomasz Glinka Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors
WO2009055696A1 (en) * 2007-10-25 2009-04-30 Achaogen, Inc. CARBACEPHEM β-LACTAM ANTIBIOTICS
WO2010030810A1 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. Carbacephem beta-lactam antibiotics
WO2010123997A1 (en) * 2009-04-22 2010-10-28 Achaogen, Inc. Carbacephem beta-lactam antibiotics
US9433621B2 (en) 2010-02-18 2016-09-06 Merck Sharp & Dohme Corp. Substituted pyridine and pyrimidine derivatives and their use in treating viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
JPS6058920B2 (ja) * 1978-12-26 1985-12-23 協和醗酵工業株式会社 セフアロスポリン類縁体
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd ３位置換カルバセフエム化合物
JPH0653739B2 (ja) * 1984-11-15 1994-07-20 協和醗酵工業株式会社 ３位置換カルバセフエム化合物
US4885291A (en) * 1988-01-14 1989-12-05 Eli Lilly And Company 1-carba(dethia)-3-cephem derivatives
IL100576A (en) * 1991-01-18 1995-11-27 Eli Lilley And Company Cephalosporin antibiotics

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