RU2764131C2 - Водорастворимые производные 3,5-дифенилдиазольных соединений - Google Patents
Водорастворимые производные 3,5-дифенилдиазольных соединений Download PDFInfo
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- RU2764131C2 RU2764131C2 RU2018125590A RU2018125590A RU2764131C2 RU 2764131 C2 RU2764131 C2 RU 2764131C2 RU 2018125590 A RU2018125590 A RU 2018125590A RU 2018125590 A RU2018125590 A RU 2018125590A RU 2764131 C2 RU2764131 C2 RU 2764131C2
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| CH713150A2 (fr) * | 2016-11-23 | 2018-05-31 | Eta Sa Mft Horlogere Suisse | Mécanisme régulateur à résonateur rotatif à guidage flexible entretenu par un échappement libre à ancre. |
| US10368502B2 (en) | 2017-09-25 | 2019-08-06 | Multiple Energy Technologies Llc | Bioceramic and carbon-based hydroponic systems, methods and devices |
| EP4368184A3 (en) | 2019-11-19 | 2024-07-31 | Modag GmbH | Novel compounds for the diagnosis, treatment and prevention of diseases associated with the aggregation of alpha-synuclein |
| US20250161273A1 (en) * | 2022-03-01 | 2025-05-22 | Modag Gmbh | Pharmaceutical composition comprising diphenyldiazole derivatives and methods of use |
| CN115337301A (zh) * | 2022-07-22 | 2022-11-15 | 汕头大学医学院第一附属医院 | Anle138b在制备改善饮食诱导胰岛素抵抗药物中的应用 |
| CN116399983B (zh) * | 2023-06-09 | 2023-08-15 | 天津辰欣药物研究有限公司 | 一种利用gc-ms法检测二叔丁基氯甲基磷酸酯残留量的方法 |
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| US20130330366A1 (en) * | 2012-06-08 | 2013-12-12 | Adam D. Hughes | Neprilysin inhibitors |
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| NZ564326A (en) * | 2005-06-16 | 2010-01-29 | Cv Therapeutics Inc | Prodrugs of A2B adenosine receptor antagonists |
| EP2272822A4 (en) * | 2008-03-31 | 2012-01-18 | Renascience Co Ltd | PLASMINOG ACTIVATOR-1 HEMMER |
| JP6069661B2 (ja) * | 2010-06-24 | 2017-02-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 種々のアミロイドβペプチドアロフォームレベルの調節における組成物及びその使用 |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2010154272A (ru) * | 2008-06-09 | 2012-07-20 | Людвиг-Максимилианс-Универзитет Мюнхен (De) | Новые лекарственные средства для ингибирования агрегации белков, вовлеченных в заболевания связанные с агрегацией белков, и нейродегенеративные заболевания |
| US20130330366A1 (en) * | 2012-06-08 | 2013-12-12 | Adam D. Hughes | Neprilysin inhibitors |
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| Christa E Muller et al. "Prodrug approaches for enhancing the bioavailability of drugs with low solubility", Chemistry & Biodiversity, 2009, 2071-2083. * |
| JARKKO RAUTIO et al. "Prodrugs: design and clinical applications", Nature Drug Descovery, 2008, vol. 7, N3, 255-270. * |
| S. JANA et al. "Prodrug design to improve pharmacokinetic and drug delivery properties: chellenges to the discovery scientists", Current Medicinal Chemistry, 2010, vol. 17, N32, 3874-3908. * |
| S. JANA et al. "Prodrug design to improve pharmacokinetic and drug delivery properties: chellenges to the discovery scientists", Current Medicinal Chemistry, 2010, vol. 17, N32, 3874-3908. JARKKO RAUTIO et al. "Prodrugs: design and clinical applications", Nature Drug Descovery, 2008, vol. 7, N3, 255-270. Christa E Muller et al. "Prodrug approaches for enhancing the bioavailability of drugs with low solubility", Chemistry & Biodiversity, 2009, 2071-2083. * |
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| DK3390412T3 (da) | 2021-06-21 |
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| MX2018006877A (es) | 2018-09-18 |
| IL260011A (en) | 2018-07-31 |
| CL2018001570A1 (es) | 2018-12-28 |
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| EP3390412B1 (en) | 2021-04-14 |
| MX379522B (es) | 2025-03-10 |
| WO2017102893A1 (en) | 2017-06-22 |
| KR102671166B1 (ko) | 2024-05-31 |
| CN108473516A (zh) | 2018-08-31 |
| RU2018125590A3 (enExample) | 2020-04-21 |
| AU2016372408A1 (en) | 2018-06-21 |
| NZ742979A (en) | 2022-05-27 |
| US10308671B2 (en) | 2019-06-04 |
| JP6898931B2 (ja) | 2021-07-07 |
| BR112018011994A2 (pt) | 2018-12-04 |
| BR112018011994B1 (pt) | 2022-07-19 |
| EP3390412A1 (en) | 2018-10-24 |
| HUE054815T2 (hu) | 2021-10-28 |
| AU2016372408B2 (en) | 2021-05-13 |
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