ZA201803865B - Water-soluble derivatives of 3,5-diphenyl-diazole compounds - Google Patents
Water-soluble derivatives of 3,5-diphenyl-diazole compoundsInfo
- Publication number
- ZA201803865B ZA201803865B ZA2018/03865A ZA201803865A ZA201803865B ZA 201803865 B ZA201803865 B ZA 201803865B ZA 2018/03865 A ZA2018/03865 A ZA 2018/03865A ZA 201803865 A ZA201803865 A ZA 201803865A ZA 201803865 B ZA201803865 B ZA 201803865B
- Authority
- ZA
- South Africa
- Prior art keywords
- diphenyl
- water
- soluble derivatives
- diazole compounds
- diazole
- Prior art date
Links
- JXHKUYQCEJILEI-UHFFFAOYSA-N 3,5-diphenyl-1h-pyrazole Chemical class C=1C(C=2C=CC=CC=2)=NNC=1C1=CC=CC=C1 JXHKUYQCEJILEI-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/11—Esters of phosphoric acids with hydroxyalkyl compounds without further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15199972 | 2015-12-14 | ||
| PCT/EP2016/081084 WO2017102893A1 (en) | 2015-12-14 | 2016-12-14 | Water-soluble derivatives of 3,5-diphenyl-diazole compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201803865B true ZA201803865B (en) | 2019-04-24 |
Family
ID=54850017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2018/03865A ZA201803865B (en) | 2015-12-14 | 2018-06-11 | Water-soluble derivatives of 3,5-diphenyl-diazole compounds |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10308671B2 (enExample) |
| EP (1) | EP3390412B1 (enExample) |
| JP (1) | JP6898931B2 (enExample) |
| KR (1) | KR102671166B1 (enExample) |
| CN (1) | CN108473516B (enExample) |
| AU (1) | AU2016372408B2 (enExample) |
| BR (1) | BR112018011994B1 (enExample) |
| CA (1) | CA3008334C (enExample) |
| CL (1) | CL2018001570A1 (enExample) |
| DK (1) | DK3390412T3 (enExample) |
| ES (1) | ES2873510T3 (enExample) |
| HU (1) | HUE054815T2 (enExample) |
| IL (1) | IL260011B (enExample) |
| MX (1) | MX379522B (enExample) |
| NZ (1) | NZ742979A (enExample) |
| PH (1) | PH12018501276A1 (enExample) |
| PL (1) | PL3390412T3 (enExample) |
| PT (1) | PT3390412T (enExample) |
| RU (1) | RU2764131C2 (enExample) |
| WO (1) | WO2017102893A1 (enExample) |
| ZA (1) | ZA201803865B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH713150A2 (fr) * | 2016-11-23 | 2018-05-31 | Eta Sa Mft Horlogere Suisse | Mécanisme régulateur à résonateur rotatif à guidage flexible entretenu par un échappement libre à ancre. |
| US10368502B2 (en) | 2017-09-25 | 2019-08-06 | Multiple Energy Technologies Llc | Bioceramic and carbon-based hydroponic systems, methods and devices |
| EP4368184A3 (en) | 2019-11-19 | 2024-07-31 | Modag GmbH | Novel compounds for the diagnosis, treatment and prevention of diseases associated with the aggregation of alpha-synuclein |
| US20250161273A1 (en) * | 2022-03-01 | 2025-05-22 | Modag Gmbh | Pharmaceutical composition comprising diphenyldiazole derivatives and methods of use |
| CN115337301A (zh) * | 2022-07-22 | 2022-11-15 | 汕头大学医学院第一附属医院 | Anle138b在制备改善饮食诱导胰岛素抵抗药物中的应用 |
| CN116399983B (zh) * | 2023-06-09 | 2023-08-15 | 天津辰欣药物研究有限公司 | 一种利用gc-ms法检测二叔丁基氯甲基磷酸酯残留量的方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7745625B2 (en) * | 2004-03-15 | 2010-06-29 | Bristol-Myers Squibb Company | Prodrugs of piperazine and substituted piperidine antiviral agents |
| NZ564326A (en) * | 2005-06-16 | 2010-01-29 | Cv Therapeutics Inc | Prodrugs of A2B adenosine receptor antagonists |
| EP2272822A4 (en) * | 2008-03-31 | 2012-01-18 | Renascience Co Ltd | PLASMINOG ACTIVATOR-1 HEMMER |
| EP2687513B1 (en) * | 2008-06-09 | 2020-12-02 | Ludwig-Maximilians-Universität München | Drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases |
| JP6069661B2 (ja) * | 2010-06-24 | 2017-02-01 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 種々のアミロイドβペプチドアロフォームレベルの調節における組成物及びその使用 |
| SMT201700306T1 (it) * | 2012-06-08 | 2017-07-18 | Theravance Biopharma R&D Ip Llc | Inibitori di neprilisina |
-
2016
- 2016-12-14 KR KR1020187020192A patent/KR102671166B1/ko active Active
- 2016-12-14 EP EP16809425.8A patent/EP3390412B1/en active Active
- 2016-12-14 CA CA3008334A patent/CA3008334C/en active Active
- 2016-12-14 BR BR112018011994-6A patent/BR112018011994B1/pt active IP Right Grant
- 2016-12-14 ES ES16809425T patent/ES2873510T3/es active Active
- 2016-12-14 HU HUE16809425A patent/HUE054815T2/hu unknown
- 2016-12-14 WO PCT/EP2016/081084 patent/WO2017102893A1/en not_active Ceased
- 2016-12-14 RU RU2018125590A patent/RU2764131C2/ru active
- 2016-12-14 MX MX2018006877A patent/MX379522B/es unknown
- 2016-12-14 CN CN201680073089.1A patent/CN108473516B/zh active Active
- 2016-12-14 DK DK16809425.8T patent/DK3390412T3/da active
- 2016-12-14 US US16/062,258 patent/US10308671B2/en active Active
- 2016-12-14 JP JP2018532323A patent/JP6898931B2/ja active Active
- 2016-12-14 PL PL16809425T patent/PL3390412T3/pl unknown
- 2016-12-14 AU AU2016372408A patent/AU2016372408B2/en active Active
- 2016-12-14 NZ NZ742979A patent/NZ742979A/en unknown
- 2016-12-14 PT PT168094258T patent/PT3390412T/pt unknown
-
2018
- 2018-06-11 ZA ZA2018/03865A patent/ZA201803865B/en unknown
- 2018-06-13 IL IL260011A patent/IL260011B/en unknown
- 2018-06-13 CL CL2018001570A patent/CL2018001570A1/es unknown
- 2018-06-14 PH PH12018501276A patent/PH12018501276A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN108473516B (zh) | 2021-06-18 |
| RU2018125590A (ru) | 2020-01-20 |
| CA3008334C (en) | 2024-01-02 |
| DK3390412T3 (da) | 2021-06-21 |
| RU2764131C2 (ru) | 2022-01-13 |
| KR20180089511A (ko) | 2018-08-08 |
| PL3390412T3 (pl) | 2021-10-25 |
| CA3008334A1 (en) | 2017-06-22 |
| PH12018501276A1 (en) | 2019-01-28 |
| ES2873510T3 (es) | 2021-11-03 |
| IL260011B (en) | 2021-12-01 |
| PT3390412T (pt) | 2021-06-22 |
| US20180370997A1 (en) | 2018-12-27 |
| MX2018006877A (es) | 2018-09-18 |
| IL260011A (en) | 2018-07-31 |
| CL2018001570A1 (es) | 2018-12-28 |
| JP2019501167A (ja) | 2019-01-17 |
| EP3390412B1 (en) | 2021-04-14 |
| MX379522B (es) | 2025-03-10 |
| WO2017102893A1 (en) | 2017-06-22 |
| KR102671166B1 (ko) | 2024-05-31 |
| CN108473516A (zh) | 2018-08-31 |
| RU2018125590A3 (enExample) | 2020-04-21 |
| AU2016372408A1 (en) | 2018-06-21 |
| NZ742979A (en) | 2022-05-27 |
| US10308671B2 (en) | 2019-06-04 |
| JP6898931B2 (ja) | 2021-07-07 |
| BR112018011994A2 (pt) | 2018-12-04 |
| BR112018011994B1 (pt) | 2022-07-19 |
| EP3390412A1 (en) | 2018-10-24 |
| HUE054815T2 (hu) | 2021-10-28 |
| AU2016372408B2 (en) | 2021-05-13 |
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