RU2728789C2 - Ингибиторы iap - Google Patents
Ингибиторы iap Download PDFInfo
- Publication number
- RU2728789C2 RU2728789C2 RU2016124658A RU2016124658A RU2728789C2 RU 2728789 C2 RU2728789 C2 RU 2728789C2 RU 2016124658 A RU2016124658 A RU 2016124658A RU 2016124658 A RU2016124658 A RU 2016124658A RU 2728789 C2 RU2728789 C2 RU 2728789C2
- Authority
- RU
- Russia
- Prior art keywords
- compound
- iap
- cell
- pharmaceutically acceptable
- acceptable salt
- Prior art date
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| WO2016097773A1 (en) | 2014-12-19 | 2016-06-23 | Children's Cancer Institute | Therapeutic iap antagonists for treating proliferative disorders |
| CN109705191B (zh) * | 2017-10-25 | 2022-04-29 | 广东东阳光药业有限公司 | Iap抑制剂及其在药物中的应用 |
| IL274598B2 (en) | 2017-11-13 | 2025-01-01 | Chia Tai Tianqing Pharmaceutical Group Co Ltd | SMAC mimetics used as IAP inhibitors and their use |
| CN112533898A (zh) | 2018-07-31 | 2021-03-19 | 日商泛美克斯股份有限公司 | 杂环化合物 |
| US20220402935A1 (en) | 2019-07-31 | 2022-12-22 | Fimecs, Inc. | Heterocyclic compound |
| US20230029259A1 (en) * | 2019-12-02 | 2023-01-26 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination of iap inhibitors and parp or mek inhibitors or other chemotherapeutic agents |
| EP4093394A1 (en) | 2020-01-20 | 2022-11-30 | Astrazeneca AB | Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer |
| AU2022463015A1 (en) | 2021-10-22 | 2024-05-09 | Tract Pharmaceuticals, Inc. | Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues |
| CN117110469B (zh) * | 2023-08-18 | 2025-12-09 | 中国检验检疫科学研究院 | 一种测定防脱发类化妆品中禁用组分的方法 |
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| US20060167066A1 (en) * | 2004-12-20 | 2006-07-27 | Genentech, Inc. | Pyrrolidine inhibitors of IAP |
| WO2008045905A1 (en) * | 2006-10-12 | 2008-04-17 | Novartis Ag | Pyrrolydine derivatives as iap inhibitors |
| WO2008134679A1 (en) * | 2007-04-30 | 2008-11-06 | Genentech, Inc. | Inhibitors of iap |
| RU2401840C2 (ru) * | 2004-07-02 | 2010-10-20 | Дженентек, Инк. | Ингибиторы iap |
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| USD690416S1 (en) | 2012-12-12 | 2013-09-24 | Pharmajet, Inc. | Needle-free syringe |
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| RU2401840C2 (ru) * | 2004-07-02 | 2010-10-20 | Дженентек, Инк. | Ингибиторы iap |
| US20060167066A1 (en) * | 2004-12-20 | 2006-07-27 | Genentech, Inc. | Pyrrolidine inhibitors of IAP |
| WO2008045905A1 (en) * | 2006-10-12 | 2008-04-17 | Novartis Ag | Pyrrolydine derivatives as iap inhibitors |
| WO2008134679A1 (en) * | 2007-04-30 | 2008-11-06 | Genentech, Inc. | Inhibitors of iap |
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