RU2718780C9 - Способы лечения рака легкого - Google Patents

Способы лечения рака легкого Download PDF

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Publication number
RU2718780C9
RU2718780C9 RU2017136863A RU2017136863A RU2718780C9 RU 2718780 C9 RU2718780 C9 RU 2718780C9 RU 2017136863 A RU2017136863 A RU 2017136863A RU 2017136863 A RU2017136863 A RU 2017136863A RU 2718780 C9 RU2718780 C9 RU 2718780C9
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RU
Russia
Prior art keywords
fra
seq
antibody
expression
patient
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RU2017136863A
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English (en)
Russian (ru)
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RU2718780C2 (ru
RU2017136863A (ru
RU2017136863A3 (https=
Inventor
Даниель Джон О'ШАННЕССИ
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Эйсай Инк.
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Publication of RU2017136863A publication Critical patent/RU2017136863A/ru
Publication of RU2017136863A3 publication Critical patent/RU2017136863A3/ru
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2017136863A 2015-04-17 2016-04-14 Способы лечения рака легкого RU2718780C9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562149184P 2015-04-17 2015-04-17
US62/149,184 2015-04-17
PCT/US2016/027497 WO2016168440A1 (en) 2015-04-17 2016-04-14 Methods for treating lung cancer

Publications (4)

Publication Number Publication Date
RU2017136863A RU2017136863A (ru) 2019-05-17
RU2017136863A3 RU2017136863A3 (https=) 2019-08-21
RU2718780C2 RU2718780C2 (ru) 2020-04-14
RU2718780C9 true RU2718780C9 (ru) 2020-07-08

Family

ID=55809240

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017136863A RU2718780C9 (ru) 2015-04-17 2016-04-14 Способы лечения рака легкого

Country Status (13)

Country Link
US (1) US20180125970A1 (https=)
EP (1) EP3283886B1 (https=)
JP (1) JP2018516244A (https=)
KR (1) KR20170137848A (https=)
CN (1) CN107624071A (https=)
AU (1) AU2016248222A1 (https=)
BR (1) BR112017022320A2 (https=)
CA (1) CA2983126A1 (https=)
IL (1) IL255079A0 (https=)
MX (1) MX2017013390A (https=)
RU (1) RU2718780C9 (https=)
SG (1) SG11201708546UA (https=)
WO (1) WO2016168440A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2172487A1 (en) * 2005-04-22 2010-04-07 Morphotek Inc. Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells
EP3153178A4 (en) * 2014-06-06 2017-12-20 Kyowa Hakko Kirin Co., Ltd. Method for treating cancer patients using folr1 targeted drug and antifolate, and drug
US10822410B2 (en) 2016-11-23 2020-11-03 Eisai R&D Management Co., Ltd. Anti-folate receptor alpha antibodies and uses thereof
CN115925952A (zh) 2018-03-13 2023-04-07 东莞凡恩世生物医药有限公司 抗叶酸受体1抗体及其用途
MA52300A (fr) * 2018-06-18 2021-04-21 Fundacio Privada Inst Dinvestigacio Oncològica De Vall Hebron Combinaison d'inhibiteurs de lif et d'agents anti-néoplasiques à base de platine à utiliser dans le traitement du cancer
CN110221052B (zh) * 2019-06-17 2022-09-23 昆山德诺瑞尔生物科技有限公司 Ppfibp1蛋白在制备肝癌术后预后评估试剂盒中的应用
IL314452A (en) * 2022-03-11 2024-09-01 Astrazeneca Ab Scoring method for anti-frα antibody-drug treatment

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2556027C (en) 2004-02-12 2015-11-24 Morphotek, Inc. Monoclonal antibodies that specifically block biological activity of a tumor antigen
EP2172487A1 (en) 2005-04-22 2010-04-07 Morphotek Inc. Antibodies with Immune Effector Activity that Internalize in Folate Receptor Alpha-Positive Cells
AU2011323124C1 (en) 2010-11-05 2016-09-22 Eisai Inc. Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers
PL2731972T3 (pl) * 2011-07-15 2018-06-29 Eisai R&D Management Co., Ltd. Przeciwciała skierowane przeciwko receptorowi folianowemu alfa i ich zastosowania

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, , найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. *
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, реферат, найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. "Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes". Oncotarget 2011;2:1227-1243. *

Also Published As

Publication number Publication date
IL255079A0 (en) 2017-12-31
US20180125970A1 (en) 2018-05-10
WO2016168440A1 (en) 2016-10-20
EP3283886B1 (en) 2020-01-15
MX2017013390A (es) 2018-06-13
AU2016248222A1 (en) 2017-11-09
BR112017022320A2 (en) 2018-07-24
RU2718780C2 (ru) 2020-04-14
SG11201708546UA (en) 2017-11-29
CN107624071A (zh) 2018-01-23
RU2017136863A (ru) 2019-05-17
JP2018516244A (ja) 2018-06-21
EP3283886A1 (en) 2018-02-21
RU2017136863A3 (https=) 2019-08-21
CA2983126A1 (en) 2016-10-20
KR20170137848A (ko) 2017-12-13

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Effective date: 20210415