RU2718780C9 - Способы лечения рака легкого - Google Patents

Способы лечения рака легкого Download PDF

Info

Publication number
RU2718780C9
RU2718780C9 RU2017136863A RU2017136863A RU2718780C9 RU 2718780 C9 RU2718780 C9 RU 2718780C9 RU 2017136863 A RU2017136863 A RU 2017136863A RU 2017136863 A RU2017136863 A RU 2017136863A RU 2718780 C9 RU2718780 C9 RU 2718780C9
Authority
RU
Russia
Prior art keywords
fra
seq
antibody
expression
patient
Prior art date
Application number
RU2017136863A
Other languages
English (en)
Russian (ru)
Other versions
RU2718780C2 (ru
RU2017136863A (ru
RU2017136863A3 (enExample
Inventor
Даниель Джон О'ШАННЕССИ
Original Assignee
Эйсай Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эйсай Инк. filed Critical Эйсай Инк.
Publication of RU2017136863A publication Critical patent/RU2017136863A/ru
Publication of RU2017136863A3 publication Critical patent/RU2017136863A3/ru
Application granted granted Critical
Publication of RU2718780C2 publication Critical patent/RU2718780C2/ru
Publication of RU2718780C9 publication Critical patent/RU2718780C9/ru

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
RU2017136863A 2015-04-17 2016-04-14 Способы лечения рака легкого RU2718780C9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562149184P 2015-04-17 2015-04-17
US62/149,184 2015-04-17
PCT/US2016/027497 WO2016168440A1 (en) 2015-04-17 2016-04-14 Methods for treating lung cancer

Publications (4)

Publication Number Publication Date
RU2017136863A RU2017136863A (ru) 2019-05-17
RU2017136863A3 RU2017136863A3 (enExample) 2019-08-21
RU2718780C2 RU2718780C2 (ru) 2020-04-14
RU2718780C9 true RU2718780C9 (ru) 2020-07-08

Family

ID=55809240

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017136863A RU2718780C9 (ru) 2015-04-17 2016-04-14 Способы лечения рака легкого

Country Status (13)

Country Link
US (1) US20180125970A1 (enExample)
EP (1) EP3283886B1 (enExample)
JP (1) JP2018516244A (enExample)
KR (1) KR20170137848A (enExample)
CN (1) CN107624071A (enExample)
AU (1) AU2016248222A1 (enExample)
BR (1) BR112017022320A2 (enExample)
CA (1) CA2983126A1 (enExample)
IL (1) IL255079A0 (enExample)
MX (1) MX2017013390A (enExample)
RU (1) RU2718780C9 (enExample)
SG (1) SG11201708546UA (enExample)
WO (1) WO2016168440A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006241099B2 (en) * 2005-04-22 2012-04-19 Eisai, Inc. Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells
WO2015186823A1 (ja) * 2014-06-06 2015-12-10 協和発酵キリン株式会社 Ｆｏｌｒ１標的薬および葉酸代謝拮抗剤によるがん患者のための治療方法並びに医薬
US10822410B2 (en) 2016-11-23 2020-11-03 Eisai R&D Management Co., Ltd. Anti-folate receptor alpha antibodies and uses thereof
CN115925952A (zh) 2018-03-13 2023-04-07 东莞凡恩世生物医药有限公司 抗叶酸受体1抗体及其用途
SG11202012576QA (en) * 2018-06-18 2021-01-28 Medimmune Ltd Combination of lif inhibitors and platinum-based antineoplastic agents for use in treating cancer
CN110221052B (zh) * 2019-06-17 2022-09-23 昆山德诺瑞尔生物科技有限公司 Ppfibp1蛋白在制备肝癌术后预后评估试剂盒中的应用
EP4490517A1 (en) * 2022-03-11 2025-01-15 Astrazeneca AB A scoring method for an anti-fr alpha antibody-drug conjugate therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005214331B2 (en) 2004-02-12 2011-09-15 Eisai, Inc. Monoclonal antibodies that specifically bind to folate receptor alpha
AU2006241099B2 (en) * 2005-04-22 2012-04-19 Eisai, Inc. Antibodies with immune effector activity and that internalize in folate receptor alpha-positive cells
WO2012061759A2 (en) 2010-11-05 2012-05-10 Morphotek Inc. Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers
CN107011439B (zh) * 2011-07-15 2020-11-10 卫材R&D管理有限公司 抗叶酸受体α抗体及其应用

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, , найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. *
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, реферат, найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. "Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes". Oncotarget 2011;2:1227-1243. *

Also Published As

Publication number Publication date
WO2016168440A1 (en) 2016-10-20
MX2017013390A (es) 2018-06-13
CN107624071A (zh) 2018-01-23
AU2016248222A1 (en) 2017-11-09
JP2018516244A (ja) 2018-06-21
KR20170137848A (ko) 2017-12-13
CA2983126A1 (en) 2016-10-20
RU2718780C2 (ru) 2020-04-14
IL255079A0 (en) 2017-12-31
RU2017136863A (ru) 2019-05-17
SG11201708546UA (en) 2017-11-29
EP3283886B1 (en) 2020-01-15
BR112017022320A2 (en) 2018-07-24
EP3283886A1 (en) 2018-02-21
US20180125970A1 (en) 2018-05-10
RU2017136863A3 (enExample) 2019-08-21

Similar Documents

Publication Publication Date Title
RU2718780C9 (ru) Способы лечения рака легкого
US8470542B2 (en) Methods and assays for measuring p95 and/or p95 complexes in a sample and antibodies specific for p95
Liu et al. Calreticulin as a potential diagnostic biomarker for lung cancer
US20190202930A1 (en) Methods for treatment of ovarian cancer
US10221240B2 (en) Methods for treatment of gastric cancer
US20190154694A1 (en) Detection and treatment of cancer
WO2022154037A1 (ja) がんの予後バイオマーカー
US12455289B2 (en) Monoclonal antibodies against loricrin
WO2019064073A1 (en) USE OF CA125 FOR PREDICTING ANTI-MESOTHELIC TREATMENT OF MESOTHELIOMES
US20250189528A1 (en) Biomarkers for disease progression and/or recurrence in squamous cell carcinoma
CN110546510A (zh) 预后方法和在所述方法中有用的试剂盒

Legal Events

Date Code Title Description
TH4A Reissue of patent specification
MM4A The patent is invalid due to non-payment of fees

Effective date: 20210415