RU2718780C9 - Способы лечения рака легкого - Google Patents

Способы лечения рака легкого Download PDF

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Publication number
RU2718780C9
RU2718780C9 RU2017136863A RU2017136863A RU2718780C9 RU 2718780 C9 RU2718780 C9 RU 2718780C9 RU 2017136863 A RU2017136863 A RU 2017136863A RU 2017136863 A RU2017136863 A RU 2017136863A RU 2718780 C9 RU2718780 C9 RU 2718780C9
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RU
Russia
Prior art keywords
fra
seq
antibody
expression
patient
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RU2017136863A
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English (en)
Russian (ru)
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RU2718780C2 (ru
RU2017136863A3 (cg-RX-API-DMAC7.html
RU2017136863A (ru
Inventor
Даниель Джон О'ШАННЕССИ
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Эйсай Инк.
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Publication of RU2017136863A publication Critical patent/RU2017136863A/ru
Publication of RU2017136863A3 publication Critical patent/RU2017136863A3/ru
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57423Specifically defined cancers of lung
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
RU2017136863A 2015-04-17 2016-04-14 Способы лечения рака легкого RU2718780C9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562149184P 2015-04-17 2015-04-17
US62/149,184 2015-04-17
PCT/US2016/027497 WO2016168440A1 (en) 2015-04-17 2016-04-14 Methods for treating lung cancer

Publications (4)

Publication Number Publication Date
RU2017136863A RU2017136863A (ru) 2019-05-17
RU2017136863A3 RU2017136863A3 (cg-RX-API-DMAC7.html) 2019-08-21
RU2718780C2 RU2718780C2 (ru) 2020-04-14
RU2718780C9 true RU2718780C9 (ru) 2020-07-08

Family

ID=55809240

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017136863A RU2718780C9 (ru) 2015-04-17 2016-04-14 Способы лечения рака легкого

Country Status (13)

Country Link
US (1) US20180125970A1 (cg-RX-API-DMAC7.html)
EP (1) EP3283886B1 (cg-RX-API-DMAC7.html)
JP (1) JP2018516244A (cg-RX-API-DMAC7.html)
KR (1) KR20170137848A (cg-RX-API-DMAC7.html)
CN (1) CN107624071A (cg-RX-API-DMAC7.html)
AU (1) AU2016248222A1 (cg-RX-API-DMAC7.html)
BR (1) BR112017022320A2 (cg-RX-API-DMAC7.html)
CA (1) CA2983126A1 (cg-RX-API-DMAC7.html)
IL (1) IL255079A0 (cg-RX-API-DMAC7.html)
MX (1) MX2017013390A (cg-RX-API-DMAC7.html)
RU (1) RU2718780C9 (cg-RX-API-DMAC7.html)
SG (1) SG11201708546UA (cg-RX-API-DMAC7.html)
WO (1) WO2016168440A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009521206A (ja) * 2005-04-22 2009-06-04 モルフォテック、インク. 免疫エフェクター活性を有する葉酸受容体アルファ陽性細胞に内部移行する抗体
TW201625301A (zh) * 2014-06-06 2016-07-16 Kyowa Hakko Kirin Co Ltd 藉由folr1標靶藥及葉酸代謝拮抗劑用於癌症患者之治療方法與醫藥
JP7072571B2 (ja) 2016-11-23 2022-05-20 エーザイ・アール・アンド・ディー・マネジメント株式会社 抗葉酸受容体アルファ抗体およびその使用
MX2020009522A (es) 2018-03-13 2020-10-22 Phanes Therapeutics Inc Anticuerpos anti-folato del receptor 1 y usos de los mismos.
CA3103369A1 (en) * 2018-06-18 2019-12-26 Medimmune Limited Combination of lif inhibitors and platinum-based antineoplastic agents for use in treating cancer
CN110221052B (zh) * 2019-06-17 2022-09-23 昆山德诺瑞尔生物科技有限公司 Ppfibp1蛋白在制备肝癌术后预后评估试剂盒中的应用
US20250177550A1 (en) * 2022-03-11 2025-06-05 Astrazeneca Ab A scoring method for an anti-fr alpha antibody drug conjugate therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050232919A1 (en) * 2004-02-12 2005-10-20 Morphotek, Inc. Monoclonal antibodies that specifically block biological activity of a tumor antigen
JP2009521206A (ja) * 2005-04-22 2009-06-04 モルフォテック、インク. 免疫エフェクター活性を有する葉酸受容体アルファ陽性細胞に内部移行する抗体
RU2630608C2 (ru) 2010-11-05 2017-09-11 Морфотек Инк. Рецептор фолиевой кислоты альфа в качестве диагностического и прогностического маркера злокачественных опухолей, экспрессирующих рецептор фолиевой кислоты альфа
PL2731972T3 (pl) 2011-07-15 2018-06-29 Eisai R&D Management Co., Ltd. Przeciwciała skierowane przeciwko receptorowi folianowemu alfa i ich zastosowania

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2529797C2 (ru) * 2007-09-18 2014-09-27 Кэнсер Рисёч Текнолоджи Лтд Раковый маркер и терапевтическая мишень

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, , найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. *
THOMAS A. et al. " Farletuzumab in lung cancer". Lung Cancer 2013 April;80(1):15-18, doi: 10/1016/j.1ungcan.2012.12.021. O'SHANNESSY DJ. et al. "Folate receptor alpha expression in lung cancer: diagnostic and prognostic significance". Oncotarget 2012 Apr;3(4):414-25, реферат, найдено 19.08.2019 из PubMed PMID:22547449. O'SHANNESSY DJ. et al. "Characterization of the Human Folate Receptor Alpha Via Novel Antibody-Based Probes". Oncotarget 2011;2:1227-1243. *

Also Published As

Publication number Publication date
EP3283886A1 (en) 2018-02-21
EP3283886B1 (en) 2020-01-15
RU2718780C2 (ru) 2020-04-14
KR20170137848A (ko) 2017-12-13
AU2016248222A1 (en) 2017-11-09
CN107624071A (zh) 2018-01-23
WO2016168440A1 (en) 2016-10-20
SG11201708546UA (en) 2017-11-29
JP2018516244A (ja) 2018-06-21
CA2983126A1 (en) 2016-10-20
US20180125970A1 (en) 2018-05-10
IL255079A0 (en) 2017-12-31
RU2017136863A3 (cg-RX-API-DMAC7.html) 2019-08-21
MX2017013390A (es) 2018-06-13
BR112017022320A2 (pt) 2018-07-24
RU2017136863A (ru) 2019-05-17

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Effective date: 20210415