RU2689388C1 - Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами - Google Patents

Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами Download PDF

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RU2689388C1
RU2689388C1 RU2016122504A RU2016122504A RU2689388C1 RU 2689388 C1 RU2689388 C1 RU 2689388C1 RU 2016122504 A RU2016122504 A RU 2016122504A RU 2016122504 A RU2016122504 A RU 2016122504A RU 2689388 C1 RU2689388 C1 RU 2689388C1
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antibody
amino acid
drug
acid sequence
seq
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RU2016122504A
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Russian (ru)
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Джон ФЛИГАРЕ
Джанет ГУНЗНЕР-ТОСТЕ
Томас Пиллоу
Брайан САФИНА
Вишал Верма
Бинкинг УЭЙ
Гуилинг ЧЖАО
Леанна Стабен
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Дженентек, Инк.
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RU2016122504A 2013-12-16 2014-12-16 Пептидомиметические соединения и их конъюгаты антител с лекарственными средствами RU2689388C1 (ru)

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US201361916680P 2013-12-16 2013-12-16
US61/916,680 2013-12-16
PCT/US2014/070654 WO2015095223A2 (en) 2013-12-16 2014-12-16 Peptidomimetic compounds and antibody-drug conjugates thereof

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UA118113C2 (uk) 2013-12-16 2018-11-26 Дженентек, Інк. Пептидоміметичні сполуки та їх кон'югати антитіла з лікарським засобом
KR102337414B1 (ko) 2013-12-16 2021-12-10 제넨테크, 인크. 펩타이드 모방체 화합물 및 이의 항체-약물 컨쥬게이트
TW201625688A (zh) 2014-09-12 2016-07-16 建南德克公司 經半胱胺酸改造之抗體及接合物
MA40579A (fr) 2014-09-12 2016-03-17 Genentech Inc Anticorps anti-cll-1 et immunoconjugués
MX2017007169A (es) * 2014-12-03 2018-05-02 Genentech Inc Compuestos de amina cuaternaria y conjugados de anticuerpofármaco de los mismos.
US10017577B2 (en) 2015-06-15 2018-07-10 Genentech, Inc. Antibodies and immunoconjugates
KR102111338B1 (ko) 2015-10-02 2020-05-15 제넨테크, 인크. 피롤로벤조디아제핀 항체 약물 콘쥬게이트 및 이의 사용 방법
CN118436801A (zh) * 2016-05-20 2024-08-06 豪夫迈·罗氏有限公司 Protac抗体缀合物及其使用方法
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