RU2685713C2 - Способ прогнозирования риска развития у субъекта сахарного диабета и/или метаболического синдрома или диагностирования метаболического синдрома у субъекта - Google Patents

Способ прогнозирования риска развития у субъекта сахарного диабета и/или метаболического синдрома или диагностирования метаболического синдрома у субъекта Download PDF

Info

Publication number
RU2685713C2
RU2685713C2 RU2014140427A RU2014140427A RU2685713C2 RU 2685713 C2 RU2685713 C2 RU 2685713C2 RU 2014140427 A RU2014140427 A RU 2014140427A RU 2014140427 A RU2014140427 A RU 2014140427A RU 2685713 C2 RU2685713 C2 RU 2685713C2
Authority
RU
Russia
Prior art keywords
subject
neurotensin
diabetes
pro
risk
Prior art date
Application number
RU2014140427A
Other languages
English (en)
Russian (ru)
Other versions
RU2014140427A (ru
Inventor
Андреас БЕРГМАНН
Олле МЕЛАНДЕР
Original Assignee
Сфинготек Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сфинготек Гмбх filed Critical Сфинготек Гмбх
Publication of RU2014140427A publication Critical patent/RU2014140427A/ru
Application granted granted Critical
Publication of RU2685713C2 publication Critical patent/RU2685713C2/ru

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2014140427A 2012-03-08 2013-03-08 Способ прогнозирования риска развития у субъекта сахарного диабета и/или метаболического синдрома или диагностирования метаболического синдрома у субъекта RU2685713C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261608350P 2012-03-08 2012-03-08
EP12158680 2012-03-08
EP12158680.4 2012-03-08
US61/608,350 2012-03-08
EP12165062 2012-04-20
EP12165062.6 2012-04-20
PCT/EP2013/054801 WO2013132090A1 (en) 2012-03-08 2013-03-08 A method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome or for diagnosing metabolic syndrome in a subject

Publications (2)

Publication Number Publication Date
RU2014140427A RU2014140427A (ru) 2016-04-27
RU2685713C2 true RU2685713C2 (ru) 2019-04-23

Family

ID=49115970

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014140427A RU2685713C2 (ru) 2012-03-08 2013-03-08 Способ прогнозирования риска развития у субъекта сахарного диабета и/или метаболического синдрома или диагностирования метаболического синдрома у субъекта

Country Status (9)

Country Link
US (2) US10520512B2 (enExample)
EP (1) EP2823316B1 (enExample)
JP (1) JP6262669B2 (enExample)
CN (1) CN103308670B (enExample)
ES (1) ES2684512T3 (enExample)
IN (1) IN2014MN01937A (enExample)
RU (1) RU2685713C2 (enExample)
TR (1) TR201811201T4 (enExample)
WO (1) WO2013132090A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022203533A1 (ru) * 2021-03-25 2022-09-29 Владимир Валерьевич ВОЛОБУЕВ Способ оценки предрасположенности к различным формам сахарного диабета 2го типа

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103308689B (zh) * 2012-03-08 2017-04-12 思芬构技术有限公司 用于预测雌性对象中患上癌症的风险或诊断癌症的方法
US20160097781A1 (en) * 2014-10-01 2016-04-07 Sphingotec Gmbh Method for stratifying a female subject for hormone replacement therapy
RU2745751C2 (ru) * 2015-02-27 2021-03-31 Сфинготек Гмбх Способ прогнозирования риска развития ожирения у субъекта
US10473670B2 (en) 2016-02-25 2019-11-12 University Of Kentucky Research Foundation Method of predicting obesity comprising measuring neurotensin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289287A2 (en) * 1987-04-27 1988-11-02 Amylin Pharmaceuticals, Inc. Amyloid peptides
US20090280501A1 (en) * 2005-04-11 2009-11-12 Astrazeneca Ab A Method And A Kit For Diagnosing Type 2 Diabetes, Metabolic Syndrome, Sub Clinical Atherosclerosis, Myocardial Infarct, Stroke Or Clinical Manifestations Of Diabetes
UA58612U (uk) * 2010-06-04 2011-04-26 Высшее Государственное Учебное Заведение «Украинская Медицинская Стоматологическая Академия» Спосіб діагностики інсулінорезистентності у хворих на метаболічний синдром та цукровий діабет 2 типу

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU634716B2 (en) 1988-08-01 1993-03-04 Ciba Corning Diagnostics Corp. Method for detection of an analyte using acridinium esters and liposomes
US5430047A (en) * 1994-04-07 1995-07-04 Warner-Lambert Company Neurotensin antagonists
US5968899A (en) * 1994-06-03 1999-10-19 Tsumura & Co. Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption
CA2321026A1 (en) * 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
US6248527B1 (en) * 1998-10-21 2001-06-19 Millennium Pharmaceuticals, Inc. Method of detecting risk of type II diabetes based on mutations found in carboxypeptidase E
US6818418B1 (en) 1998-12-10 2004-11-16 Compound Therapeutics, Inc. Protein scaffolds for antibody mimics and other binding proteins
IL142707A0 (en) * 2000-04-27 2002-03-10 Pfizer Prod Inc Methods of treating obesity using a neurotensin receptor ligand
US7271153B2 (en) * 2001-06-20 2007-09-18 Kissei Pharmaceutical Co., Ltd. Nitrogenous heterocyclic derivatives, medicinal compositions containing the same, medicinal uses thereof, and intermediates therefor
WO2003020746A1 (en) 2001-08-30 2003-03-13 Biorexis Pharmaceutical Corporation Modified transferrin fusion proteins
EP2298278B1 (en) 2002-06-07 2015-11-11 Dyax Corp. Prevention and reduction of blood loss and inflammatory response
EP1675878A2 (en) 2003-10-24 2006-07-05 Avidia, Inc. Ldl receptor class a and egf domain monomers and multimers
US20100028995A1 (en) 2004-02-23 2010-02-04 Anaphore, Inc. Tetranectin Trimerizing Polypeptides
EP1793847A2 (en) 2004-09-21 2007-06-13 NascaCell IP GmbH Use of microproteins as tryptase inhibitors
DE102005003687A1 (de) * 2005-01-26 2006-07-27 Sphingo Tec Gmbh Immunoassay zur Bestimmung der Freisetzung von Neurotensin in die Zirkulation
US8119358B2 (en) * 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
EP2231860B1 (en) 2007-12-19 2011-10-05 Affibody AB Polypeptide derived from protein a and able to bind pdgf
MX359570B (es) 2008-11-03 2018-10-01 Molecular Partners Ag Proteinas de union que inhiben la interaccion en el receptor de vegf-a.
MX2011005963A (es) * 2008-12-05 2011-09-01 Angiochem Inc Conjugados de neurotensina o analogos de neurotensina y sus usos.
EP2374003B1 (en) 2009-01-07 2015-03-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the treatment, the prognostic assessment and the detection of breast cancer
US9376477B2 (en) 2009-08-27 2016-06-28 Covagen Ag IL-17 binding compounds and medical uses thereof
JP2013509588A (ja) * 2009-10-29 2013-03-14 テシス バイオサイエンス， インコーポレイテッド ２型糖尿病の予防に対して一貫した改善をもたらすタンパク質バイオマーカーおよび脂質代謝物バイオマーカー
WO2011073214A2 (en) 2009-12-14 2011-06-23 Scil Proteins Gmbh A method for identifying hetero-multimeric modified ubiquitin proteins with binding capability to ligands
JP5902679B2 (ja) 2010-06-08 2016-04-13 ピエリス アーゲーＰｉｅｒｉｓ Ａｇ ＩＬ−４Ｒαに結合する涙液リポカリンムテイン
RU2745751C2 (ru) * 2015-02-27 2021-03-31 Сфинготек Гмбх Способ прогнозирования риска развития ожирения у субъекта

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289287A2 (en) * 1987-04-27 1988-11-02 Amylin Pharmaceuticals, Inc. Amyloid peptides
US20090280501A1 (en) * 2005-04-11 2009-11-12 Astrazeneca Ab A Method And A Kit For Diagnosing Type 2 Diabetes, Metabolic Syndrome, Sub Clinical Atherosclerosis, Myocardial Infarct, Stroke Or Clinical Manifestations Of Diabetes
UA58612U (uk) * 2010-06-04 2011-04-26 Высшее Государственное Учебное Заведение «Украинская Медицинская Стоматологическая Академия» Спосіб діагностики інсулінорезистентності у хворих на метаболічний синдром та цукровий діабет 2 типу

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
M.H. Fernstrom et al. Immunoreactive neurotensin levels in pancreas: Elevation in diabetic rats and mice. Metabolism, 1981, vol. 30, is. 9, pages 853-855. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022203533A1 (ru) * 2021-03-25 2022-09-29 Владимир Валерьевич ВОЛОБУЕВ Способ оценки предрасположенности к различным формам сахарного диабета 2го типа

Also Published As

Publication number Publication date
JP2015512048A (ja) 2015-04-23
EP2823316B1 (en) 2018-05-23
CN103308670B (zh) 2017-06-09
JP6262669B2 (ja) 2018-01-17
US20150056203A1 (en) 2015-02-26
ES2684512T3 (es) 2018-10-03
CN103308670A (zh) 2013-09-18
US10520512B2 (en) 2019-12-31
EP2823316A1 (en) 2015-01-14
RU2014140427A (ru) 2016-04-27
IN2014MN01937A (enExample) 2015-07-10
TR201811201T4 (tr) 2018-09-21
US20200326350A1 (en) 2020-10-15
WO2013132090A1 (en) 2013-09-12

Similar Documents

Publication Publication Date Title
US20210109102A1 (en) Method for predicting the risk of getting cancer or diagnosing cancer in a female subject
RU2652304C2 (ru) Способ прогнозирования риска развития сердечно-сосудистой патологии у особи женского пола
US20200326350A1 (en) Method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome or for diagnosing metabolic syndrome in a subject
ES2879023T3 (es) Niveles en ayunas de la hormona de crecimiento como marcador predictivo de riesgo cardiovascular
EP2904398B1 (en) A method for predicting the risk of getting cancer in a female subject
HK1189658B (en) A method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome
HK1189658A (en) A method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome
HK1189656B (en) A method for predicting the risk of getting cancer or diagnosing cancer in a female subject
HK1189656A (en) A method for predicting the risk of getting cancer or diagnosing cancer in a female subject
HK1189659A (en) A method for predicting the risk of getting a cardiovascular event in a female subject
HK1189659B (en) A method for predicting the risk of getting a cardiovascular event in a female subject