JP6262669B2 - 対象が糖尿病及び／又はメタボリックシンドロームに罹患するリスクを予測するために、あるいは対象のメタボリックシンドローム発症の指標とするために、体液中のプロニューロテンシン１−１１７を検出する方法 - Google Patents

対象が糖尿病及び／又はメタボリックシンドロームに罹患するリスクを予測するために、あるいは対象のメタボリックシンドローム発症の指標とするために、体液中のプロニューロテンシン１−１１７を検出する方法 Download PDF

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JP6262669B2
JP6262669B2 JP2014560405A JP2014560405A JP6262669B2 JP 6262669 B2 JP6262669 B2 JP 6262669B2 JP 2014560405 A JP2014560405 A JP 2014560405A JP 2014560405 A JP2014560405 A JP 2014560405A JP 6262669 B2 JP6262669 B2 JP 6262669B2
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diabetes
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metabolic syndrome
proneurotensin
suffering
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JP2015512048A (ja
JP2015512048A5 (enExample
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ベルクマン アンドレアス
ベルクマン アンドレアス
メランデル ウッレ
メランデル ウッレ
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シュピーンゴテック ゲゼルシャフト ミット ベシュレンクテル ハフツング
シュピーンゴテック ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4706—Regulators; Modulating activity stimulating, promoting or activating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
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  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014560405A 2012-03-08 2013-03-08 対象が糖尿病及び／又はメタボリックシンドロームに罹患するリスクを予測するために、あるいは対象のメタボリックシンドローム発症の指標とするために、体液中のプロニューロテンシン１−１１７を検出する方法 Active JP6262669B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261608350P 2012-03-08 2012-03-08
EP12158680 2012-03-08
EP12158680.4 2012-03-08
US61/608,350 2012-03-08
EP12165062 2012-04-20
EP12165062.6 2012-04-20
PCT/EP2013/054801 WO2013132090A1 (en) 2012-03-08 2013-03-08 A method for predicting the risk of a subject for contracting diabetes mellitus and/or metabolic syndrome or for diagnosing metabolic syndrome in a subject

Publications (3)

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JP2015512048A JP2015512048A (ja) 2015-04-23
JP2015512048A5 JP2015512048A5 (enExample) 2015-11-05
JP6262669B2 true JP6262669B2 (ja) 2018-01-17

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JP2014560405A Active JP6262669B2 (ja) 2012-03-08 2013-03-08 対象が糖尿病及び／又はメタボリックシンドロームに罹患するリスクを予測するために、あるいは対象のメタボリックシンドローム発症の指標とするために、体液中のプロニューロテンシン１−１１７を検出する方法

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US (2) US10520512B2 (enExample)
EP (1) EP2823316B1 (enExample)
JP (1) JP6262669B2 (enExample)
CN (1) CN103308670B (enExample)
ES (1) ES2684512T3 (enExample)
IN (1) IN2014MN01937A (enExample)
RU (1) RU2685713C2 (enExample)
TR (1) TR201811201T4 (enExample)
WO (1) WO2013132090A1 (enExample)

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CN103308689B (zh) * 2012-03-08 2017-04-12 思芬构技术有限公司 用于预测雌性对象中患上癌症的风险或诊断癌症的方法
US20160097781A1 (en) * 2014-10-01 2016-04-07 Sphingotec Gmbh Method for stratifying a female subject for hormone replacement therapy
RU2745751C2 (ru) * 2015-02-27 2021-03-31 Сфинготек Гмбх Способ прогнозирования риска развития ожирения у субъекта
US10473670B2 (en) 2016-02-25 2019-11-12 University Of Kentucky Research Foundation Method of predicting obesity comprising measuring neurotensin
WO2022203533A1 (ru) * 2021-03-25 2022-09-29 Владимир Валерьевич ВОЛОБУЕВ Способ оценки предрасположенности к различным формам сахарного диабета 2го типа

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US5430047A (en) * 1994-04-07 1995-07-04 Warner-Lambert Company Neurotensin antagonists
US5968899A (en) * 1994-06-03 1999-10-19 Tsumura & Co. Medicinal compositions of peptides with EACA or tranexamic acid for enhanced mucosal absorption
CA2321026A1 (en) * 1998-03-09 1999-09-16 Zealand Pharmaceuticals A/S Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis
US6248527B1 (en) * 1998-10-21 2001-06-19 Millennium Pharmaceuticals, Inc. Method of detecting risk of type II diabetes based on mutations found in carboxypeptidase E
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IL142707A0 (en) * 2000-04-27 2002-03-10 Pfizer Prod Inc Methods of treating obesity using a neurotensin receptor ligand
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UA58612U (uk) * 2010-06-04 2011-04-26 Высшее Государственное Учебное Заведение «Украинская Медицинская Стоматологическая Академия» Спосіб діагностики інсулінорезистентності у хворих на метаболічний синдром та цукровий діабет 2 типу
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RU2745751C2 (ru) * 2015-02-27 2021-03-31 Сфинготек Гмбх Способ прогнозирования риска развития ожирения у субъекта

Also Published As

Publication number Publication date
JP2015512048A (ja) 2015-04-23
EP2823316B1 (en) 2018-05-23
RU2685713C2 (ru) 2019-04-23
CN103308670B (zh) 2017-06-09
US20150056203A1 (en) 2015-02-26
ES2684512T3 (es) 2018-10-03
CN103308670A (zh) 2013-09-18
US10520512B2 (en) 2019-12-31
EP2823316A1 (en) 2015-01-14
RU2014140427A (ru) 2016-04-27
IN2014MN01937A (enExample) 2015-07-10
TR201811201T4 (tr) 2018-09-21
US20200326350A1 (en) 2020-10-15
WO2013132090A1 (en) 2013-09-12

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