RU2667634C2 - Способы диагностики хронического заболевания клапанов - Google Patents

Способы диагностики хронического заболевания клапанов Download PDF

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RU2667634C2
RU2667634C2 RU2014153109A RU2014153109A RU2667634C2 RU 2667634 C2 RU2667634 C2 RU 2667634C2 RU 2014153109 A RU2014153109 A RU 2014153109A RU 2014153109 A RU2014153109 A RU 2014153109A RU 2667634 C2 RU2667634 C2 RU 2667634C2
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sample
animal
valve disease
amount
metabolites
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RU2014153109A
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RU2014153109A (ru
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Цинхун ЛИ
Дороти П. ЛАФЛАМ
Стивен С. ХАННА
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Нестек Са
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6806—Determination of free amino acids
    • G01N33/6812—Assays for specific amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/326—Arrhythmias, e.g. ventricular fibrillation, tachycardia, atrioventricular block, torsade de pointes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/16—Phosphorus containing
    • Y10T436/163333—Organic [e.g., chemical warfare agents, insecticides, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
RU2014153109A 2012-06-05 2013-06-04 Способы диагностики хронического заболевания клапанов RU2667634C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261655704P 2012-06-05 2012-06-05
US61/655,704 2012-06-05
PCT/US2013/044008 WO2013184628A1 (en) 2012-06-05 2013-06-04 Methods for diagnosing chronic valvular disease

Publications (2)

Publication Number Publication Date
RU2014153109A RU2014153109A (ru) 2016-08-10
RU2667634C2 true RU2667634C2 (ru) 2018-09-21

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US (1) US20150153353A1 (enExample)
EP (1) EP2856170B1 (enExample)
JP (1) JP6174689B2 (enExample)
CN (1) CN104364658B (enExample)
AU (1) AU2013271879B2 (enExample)
BR (1) BR112014030243B1 (enExample)
CA (1) CA2875331C (enExample)
ES (1) ES2687979T3 (enExample)
IN (1) IN2014DN10127A (enExample)
MX (1) MX358561B (enExample)
RU (1) RU2667634C2 (enExample)
WO (1) WO2013184628A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826160C2 (ru) * 2018-12-27 2024-09-05 Сосьете Де Продюи Нестле Са Композиции и способы диагностики и лечения дегенеративного заболевания митрального клапана у животного из семейства собачьих

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10184932B2 (en) * 2015-12-07 2019-01-22 Zora Biosciences Oy Use of ceramides and LPLs in diagnosing CVD

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2435165C2 (ru) * 2005-01-25 2011-11-27 СиАйЭс БАЙОТЕК, ИНК. Биомаркеры ишемии и их применение для прогнозирования неблагоприятных неврологических последствий хирургической операции

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009243094B2 (en) * 2006-11-06 2015-02-12 Massachusetts Institute Of Technology Immunomodulating compositions and methods of use thereof
MX2010000414A (es) * 2007-07-17 2010-04-01 Metabolon Inc Biomarcadores para prediabetes, enfermedades cardiovasculares y otros trastornos relacionados con sindrome metabolico, y metodos de uso de los mismos.
MX2010005166A (es) * 2007-11-09 2010-10-07 Univ Texas Micro arn de la familia mir-15 que modulan la sobrevivencia de cardiomiocitos y reparacion cardiaca.
WO2009136157A2 (en) * 2008-05-07 2009-11-12 University Of Strathclyde A system and method for cell characterisation
CN102369217A (zh) * 2009-01-29 2012-03-07 雅培制药有限公司 Il-1结合蛋白
SG10201505724SA (en) * 2010-07-23 2015-09-29 Harvard College Methods of detecting diseases or conditions using phagocytic cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2435165C2 (ru) * 2005-01-25 2011-11-27 СиАйЭс БАЙОТЕК, ИНК. Биомаркеры ишемии и их применение для прогнозирования неблагоприятных неврологических последствий хирургической операции

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ATKINS C. et al, Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease, J Vet Intern Med., 2009, 23, pp.1142-1150, найдено 30.05.2017 в Интернете [on-line] на сайте http://www.ivis.org/proceedings/acvim/consensus/caninevalvularheartdz.pdf. *
КЛЮЕВ Н. А. и др. Современные методы масс-спектрометрического анализа органических соединений. Ж. Рос. хим. об-ва им. Д.И. Менделеева, 2002, XLVI, 4, стр. 57-63, найдено 30.05.2017 в Интернете [on-line] на сайте http://www.chem.msu.su/rus/jvho/2002-4/57.pdf. *
СКВОРЦОВ В.В. и др. Актуальные вопросы диагностики и лечения язвенной болезни желудка и 12-перстной кишки. Больница, 2010, 4, стр. 13-17, найдено 30.05.2017 в Интернете [on-line] на сайте http://www.gastroscan.ru/literature/authors/4232. *
ШЕСТОПАЛОВА И.М. и др. Принципы диагностики и лечения карциноидной болезни сердца при нейроэндокринных опухолях. Вестник РОНЦ им. Н. Н. Блохина РАМН, 2011, 3, 22, стр. 21-26, найдено 30.05.2017 в Интернете [on-line] на сайте http://cyberleninka.ru/article/n/printsipy-diagnostiki-i-lecheniya-kartsinoidnoy-bolezni-serdtsa-pri-neyroendokrinnyh-opuholyah. *
ШЕСТОПАЛОВА И.М. и др. Принципы диагностики и лечения карциноидной болезни сердца при нейроэндокринных опухолях. Вестник РОНЦ им. Н. Н. Блохина РАМН, 2011, 3, 22, стр. 21-26, найдено 30.05.2017 в Интернете [on-line] на сайте http://cyberleninka.ru/article/n/printsipy-diagnostiki-i-lecheniya-kartsinoidnoy-bolezni-serdtsa-pri-neyroendokrinnyh-opuholyah. КЛЮЕВ Н. А. и др. Современные методы масс-спектрометрического анализа органических соединений. Ж. Рос. хим. об-ва им. Д.И. Менделеева, 2002, XLVI, 4, стр. 57-63, найдено 30.05.2017 в Интернете [on-line] на сайте http://www.chem.msu.su/rus/jvho/2002-4/57.pdf. СКВОРЦОВ В.В. и др. Актуальные вопросы диагностики и лечения язвенной болезни желудка и 12-перстной кишки. Больница, 2010, 4, стр. 13-17, найдено 30.05.2017 в Интернете [on-line] на сайте http://www.gastroscan.ru/literature/authors/4232. ATKINS C. et al, Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease, J Vet Intern Med., 2009, 23, pp.1142-1150, найд *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2826160C2 (ru) * 2018-12-27 2024-09-05 Сосьете Де Продюи Нестле Са Композиции и способы диагностики и лечения дегенеративного заболевания митрального клапана у животного из семейства собачьих

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BR112014030243A2 (pt) 2017-06-27
US20150153353A1 (en) 2015-06-04
MX358561B (es) 2018-08-24
ES2687979T3 (es) 2018-10-30
EP2856170A1 (en) 2015-04-08
CN104364658A (zh) 2015-02-18
AU2013271879B2 (en) 2019-03-28
BR112014030243B1 (pt) 2022-07-05
JP6174689B2 (ja) 2017-08-02
CA2875331A1 (en) 2013-12-12
JP2015524066A (ja) 2015-08-20
CA2875331C (en) 2022-11-29
EP2856170B1 (en) 2018-07-25
WO2013184628A1 (en) 2013-12-12
CN104364658B (zh) 2017-06-30
RU2014153109A (ru) 2016-08-10
IN2014DN10127A (enExample) 2015-08-21
MX2014014791A (es) 2015-02-24
AU2013271879A1 (en) 2014-12-18

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