RU2658461C2 - Ингибиторы ангиотензинпревращающего фермента для лечения нейропатии зрительного нерва или врождённой атрофии зрительного нерва - Google Patents

Ингибиторы ангиотензинпревращающего фермента для лечения нейропатии зрительного нерва или врождённой атрофии зрительного нерва Download PDF

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RU2658461C2
RU2658461C2 RU2014152906A RU2014152906A RU2658461C2 RU 2658461 C2 RU2658461 C2 RU 2658461C2 RU 2014152906 A RU2014152906 A RU 2014152906A RU 2014152906 A RU2014152906 A RU 2014152906A RU 2658461 C2 RU2658461 C2 RU 2658461C2
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ace
inhibitor
converting enzyme
angiotensin converting
optic
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RU2014152906A
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Russian (ru)
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RU2014152906A (ru
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Рауф РЕКИК
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Рауф РЕКИК
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
RU2014152906A 2012-06-29 2013-06-28 Ингибиторы ангиотензинпревращающего фермента для лечения нейропатии зрительного нерва или врождённой атрофии зрительного нерва RU2658461C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
TN20120343 2012-06-29
TNTN2012/0343 2012-06-29
PCT/IB2013/001375 WO2014001889A1 (en) 2012-06-29 2013-06-28 Angiotensin converting enzyme inhibitors for treating optic neuropathy or congenital optic atrophy

Publications (2)

Publication Number Publication Date
RU2014152906A RU2014152906A (ru) 2016-08-20
RU2658461C2 true RU2658461C2 (ru) 2018-06-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014152906A RU2658461C2 (ru) 2012-06-29 2013-06-28 Ингибиторы ангиотензинпревращающего фермента для лечения нейропатии зрительного нерва или врождённой атрофии зрительного нерва

Country Status (7)

Country Link
US (1) US9730949B2 (enExample)
EP (1) EP2866805A1 (enExample)
JP (1) JP6238977B2 (enExample)
CA (1) CA2877590A1 (enExample)
RU (1) RU2658461C2 (enExample)
WO (1) WO2014001889A1 (enExample)
ZA (1) ZA201500103B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2704013C1 (ru) * 2019-04-18 2019-10-23 ФГБНУ "НИИ глазных болезней" Способ коррекции окислительного стресса при наследственной оптической нейропатии Лебера

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108452309B (zh) * 2018-03-05 2019-08-23 佳木斯大学附属第一医院 一种用于预防或治疗视神经炎的药物组合物及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0220107A2 (en) * 1985-10-09 1987-04-29 Merck & Co. Inc. Use of angiotensin-converting enzyme inhibitors in macular degeneration
WO2000076499A2 (fr) * 1999-06-16 2000-12-21 Rekik, Elyes, Ben, Mohamed, Raouf Medicaments ophtalmologiques neuro-et retino-protecteurs
FR2826276A1 (fr) * 2001-06-20 2002-12-27 Raouf Rekik Administration des inhibiteurs de l'enzyme de conversion de l'angiotensine dans les degradations visuelles des sujets ages dues a la presbytie
RU2281023C2 (ru) * 2004-10-26 2006-08-10 Наталия Ивановна Курышева Способ прогнозирования течения глаукоматозной оптической нейропатии

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010126911A1 (en) 2009-04-28 2010-11-04 Edison Pharmaceuticals, Inc. Treatment of leber's hereditary optic neuropathy and dominant optic atrophy with tocotrienol quinones
TN2010000251A1 (fr) 2010-06-03 2011-11-11 Rekik Raouf N-acetyl-dl-leucine medicament neuro et retino protecteur

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0220107A2 (en) * 1985-10-09 1987-04-29 Merck & Co. Inc. Use of angiotensin-converting enzyme inhibitors in macular degeneration
WO2000076499A2 (fr) * 1999-06-16 2000-12-21 Rekik, Elyes, Ben, Mohamed, Raouf Medicaments ophtalmologiques neuro-et retino-protecteurs
FR2826276A1 (fr) * 2001-06-20 2002-12-27 Raouf Rekik Administration des inhibiteurs de l'enzyme de conversion de l'angiotensine dans les degradations visuelles des sujets ages dues a la presbytie
RU2281023C2 (ru) * 2004-10-26 2006-08-10 Наталия Ивановна Курышева Способ прогнозирования течения глаукоматозной оптической нейропатии

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
RYU S et al. Mitigation of radiation-induced optic neuropathy in rats by ACE inhibitor ramipril: importance of ramipril dose and treatment time. J Neurooncol, 2007, 82(2), p.119-24. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2704013C1 (ru) * 2019-04-18 2019-10-23 ФГБНУ "НИИ глазных болезней" Способ коррекции окислительного стресса при наследственной оптической нейропатии Лебера

Also Published As

Publication number Publication date
US9730949B2 (en) 2017-08-15
JP2015522000A (ja) 2015-08-03
WO2014001889A1 (en) 2014-01-03
ZA201500103B (en) 2016-05-25
EP2866805A1 (en) 2015-05-06
RU2014152906A (ru) 2016-08-20
US20150174146A1 (en) 2015-06-25
CA2877590A1 (en) 2014-01-03
JP6238977B2 (ja) 2017-11-29

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Effective date: 20200629