RU2654461C2 - Получение промежуточного соединения синтеза иоформинола - Google Patents
Получение промежуточного соединения синтеза иоформинола Download PDFInfo
- Publication number
- RU2654461C2 RU2654461C2 RU2015107016A RU2015107016A RU2654461C2 RU 2654461 C2 RU2654461 C2 RU 2654461C2 RU 2015107016 A RU2015107016 A RU 2015107016A RU 2015107016 A RU2015107016 A RU 2015107016A RU 2654461 C2 RU2654461 C2 RU 2654461C2
- Authority
- RU
- Russia
- Prior art keywords
- mixture
- compounds
- compound
- chain alcohol
- bis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20121102 | 2012-09-27 | ||
| NO20121102 | 2012-09-27 | ||
| PCT/US2013/060081 WO2014052091A1 (en) | 2012-09-27 | 2013-09-17 | Preparation of an intermediate compound of ioforminol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015107016A RU2015107016A (ru) | 2016-11-20 |
| RU2654461C2 true RU2654461C2 (ru) | 2018-05-18 |
Family
ID=49274871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015107016A RU2654461C2 (ru) | 2012-09-27 | 2013-09-17 | Получение промежуточного соединения синтеза иоформинола |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9884808B2 (enExample) |
| EP (1) | EP2900632B1 (enExample) |
| JP (1) | JP6431842B2 (enExample) |
| KR (1) | KR20150061635A (enExample) |
| CN (2) | CN110003038A (enExample) |
| AU (1) | AU2013323981B2 (enExample) |
| BR (1) | BR112015004591A2 (enExample) |
| CA (1) | CA2881852A1 (enExample) |
| IN (1) | IN2015DN01185A (enExample) |
| MX (1) | MX354604B (enExample) |
| RU (1) | RU2654461C2 (enExample) |
| WO (1) | WO2014052091A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150061635A (ko) | 2012-09-27 | 2015-06-04 | 지이 헬스케어 에이에스 | 아이오포르미놀의 중간체 화합물의 제조법 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000047549A1 (en) * | 1999-02-11 | 2000-08-17 | Nycomed Imaging As | Preparation of iodixanol |
| WO2009008734A2 (en) * | 2007-07-12 | 2009-01-15 | Ge Healthcare As | Contrast agents |
| RU2385316C2 (ru) * | 2004-08-09 | 2010-03-27 | Джи-И Хелткер АС | Получение иодиксанола |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0108638B1 (en) | 1982-11-08 | 1986-07-16 | NYEGAARD & CO. A/S | X-ray contrast agents |
| WO1997000240A1 (en) | 1995-06-16 | 1997-01-03 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
| GB9624612D0 (en) | 1996-11-26 | 1997-01-15 | Nycomed Imaging As | Process |
| NO20053687D0 (no) | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
| US20110021822A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents |
| KR20150061635A (ko) | 2012-09-27 | 2015-06-04 | 지이 헬스케어 에이에스 | 아이오포르미놀의 중간체 화합물의 제조법 |
| AU2013323982B2 (en) * | 2012-09-27 | 2017-11-23 | Ge Healthcare As | Preparation of Ioforminol, an X-ray contrast agent |
-
2013
- 2013-09-17 KR KR1020157007427A patent/KR20150061635A/ko not_active Ceased
- 2013-09-17 CA CA2881852A patent/CA2881852A1/en not_active Abandoned
- 2013-09-17 CN CN201910145184.3A patent/CN110003038A/zh active Pending
- 2013-09-17 US US14/430,155 patent/US9884808B2/en not_active Expired - Fee Related
- 2013-09-17 BR BR112015004591A patent/BR112015004591A2/pt not_active Application Discontinuation
- 2013-09-17 WO PCT/US2013/060081 patent/WO2014052091A1/en not_active Ceased
- 2013-09-17 CN CN201380050455.8A patent/CN104661996A/zh active Pending
- 2013-09-17 MX MX2015003912A patent/MX354604B/es active IP Right Grant
- 2013-09-17 RU RU2015107016A patent/RU2654461C2/ru not_active IP Right Cessation
- 2013-09-17 EP EP13771008.3A patent/EP2900632B1/en active Active
- 2013-09-17 AU AU2013323981A patent/AU2013323981B2/en not_active Ceased
- 2013-09-17 JP JP2015534549A patent/JP6431842B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-13 IN IN1185DEN2015 patent/IN2015DN01185A/en unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000047549A1 (en) * | 1999-02-11 | 2000-08-17 | Nycomed Imaging As | Preparation of iodixanol |
| RU2385316C2 (ru) * | 2004-08-09 | 2010-03-27 | Джи-И Хелткер АС | Получение иодиксанола |
| WO2009008734A2 (en) * | 2007-07-12 | 2009-01-15 | Ge Healthcare As | Contrast agents |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2900632B1 (en) | 2019-10-30 |
| US20150246871A1 (en) | 2015-09-03 |
| JP6431842B2 (ja) | 2018-11-28 |
| US9884808B2 (en) | 2018-02-06 |
| RU2015107016A (ru) | 2016-11-20 |
| MX354604B (es) | 2018-03-07 |
| KR20150061635A (ko) | 2015-06-04 |
| EP2900632A1 (en) | 2015-08-05 |
| JP2015532280A (ja) | 2015-11-09 |
| CN104661996A (zh) | 2015-05-27 |
| AU2013323981B2 (en) | 2017-09-14 |
| AU2013323981A1 (en) | 2015-03-05 |
| WO2014052091A1 (en) | 2014-04-03 |
| CA2881852A1 (en) | 2014-04-03 |
| CN110003038A (zh) | 2019-07-12 |
| MX2015003912A (es) | 2015-08-05 |
| BR112015004591A2 (pt) | 2017-07-04 |
| IN2015DN01185A (enExample) | 2015-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20200918 |