MX354604B - Preparacion de un compuesto intermediario de ioforminol. - Google Patents
Preparacion de un compuesto intermediario de ioforminol.Info
- Publication number
- MX354604B MX354604B MX2015003912A MX2015003912A MX354604B MX 354604 B MX354604 B MX 354604B MX 2015003912 A MX2015003912 A MX 2015003912A MX 2015003912 A MX2015003912 A MX 2015003912A MX 354604 B MX354604 B MX 354604B
- Authority
- MX
- Mexico
- Prior art keywords
- preparation
- ioforminol
- relates
- intermediate compound
- bis
- Prior art date
Links
- BFVVDRUCXCIALU-UHFFFAOYSA-N 5-[[3-[3,5-bis(2,3-dihydroxypropylcarbamoyl)-n-formyl-2,4,6-triiodoanilino]-2-hydroxypropyl]-formylamino]-1-n,3-n-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide Chemical compound OCC(O)CNC(=O)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(N(CC(O)CN(C=O)C=2C(=C(C(=O)NCC(O)CO)C(I)=C(C(=O)NCC(O)CO)C=2I)I)C=O)=C1I BFVVDRUCXCIALU-UHFFFAOYSA-N 0.000 title abstract 3
- 229950004332 ioforminol Drugs 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000002872 contrast media Substances 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000010626 work up procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
- C07C231/24—Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20121102 | 2012-09-27 | ||
| PCT/US2013/060081 WO2014052091A1 (en) | 2012-09-27 | 2013-09-17 | Preparation of an intermediate compound of ioforminol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015003912A MX2015003912A (es) | 2015-08-05 |
| MX354604B true MX354604B (es) | 2018-03-07 |
Family
ID=49274871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015003912A MX354604B (es) | 2012-09-27 | 2013-09-17 | Preparacion de un compuesto intermediario de ioforminol. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9884808B2 (enExample) |
| EP (1) | EP2900632B1 (enExample) |
| JP (1) | JP6431842B2 (enExample) |
| KR (1) | KR20150061635A (enExample) |
| CN (2) | CN110003038A (enExample) |
| AU (1) | AU2013323981B2 (enExample) |
| BR (1) | BR112015004591A2 (enExample) |
| CA (1) | CA2881852A1 (enExample) |
| IN (1) | IN2015DN01185A (enExample) |
| MX (1) | MX354604B (enExample) |
| RU (1) | RU2654461C2 (enExample) |
| WO (1) | WO2014052091A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2900632B1 (en) | 2012-09-27 | 2019-10-30 | Ge Healthcare As | Preparation of an intermediate compound of ioforminol |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0108638B1 (en) | 1982-11-08 | 1986-07-16 | NYEGAARD & CO. A/S | X-ray contrast agents |
| WO1997000240A1 (en) | 1995-06-16 | 1997-01-03 | Biophysica Foundation | Formyl derivatives as nonionic contrast media |
| GB9624612D0 (en) | 1996-11-26 | 1997-01-15 | Nycomed Imaging As | Process |
| GB9903109D0 (en) * | 1999-02-11 | 1999-04-07 | Nycomed Imaging As | Process |
| NO20043305D0 (no) | 2004-08-09 | 2004-08-09 | Amersham Health As | Preparation of lodixanol |
| NO20053687D0 (no) * | 2005-07-29 | 2005-07-29 | Amersham Health As | Crystallisation Process. |
| KR20100033405A (ko) * | 2007-07-12 | 2010-03-29 | 지이 헬스케어 에이에스 | 조영제 |
| US20110021822A1 (en) * | 2009-07-21 | 2011-01-27 | Ge Healthcare As | continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents |
| JP6325547B2 (ja) * | 2012-09-27 | 2018-05-16 | ジーイー・ヘルスケア・アクスイェ・セルスカプ | Ｘ線造影剤イオホルミノールの調製 |
| EP2900632B1 (en) | 2012-09-27 | 2019-10-30 | Ge Healthcare As | Preparation of an intermediate compound of ioforminol |
-
2013
- 2013-09-17 EP EP13771008.3A patent/EP2900632B1/en active Active
- 2013-09-17 BR BR112015004591A patent/BR112015004591A2/pt not_active Application Discontinuation
- 2013-09-17 JP JP2015534549A patent/JP6431842B2/ja not_active Expired - Fee Related
- 2013-09-17 MX MX2015003912A patent/MX354604B/es active IP Right Grant
- 2013-09-17 US US14/430,155 patent/US9884808B2/en not_active Expired - Fee Related
- 2013-09-17 CA CA2881852A patent/CA2881852A1/en not_active Abandoned
- 2013-09-17 WO PCT/US2013/060081 patent/WO2014052091A1/en not_active Ceased
- 2013-09-17 KR KR1020157007427A patent/KR20150061635A/ko not_active Ceased
- 2013-09-17 AU AU2013323981A patent/AU2013323981B2/en not_active Ceased
- 2013-09-17 CN CN201910145184.3A patent/CN110003038A/zh active Pending
- 2013-09-17 RU RU2015107016A patent/RU2654461C2/ru not_active IP Right Cessation
- 2013-09-17 CN CN201380050455.8A patent/CN104661996A/zh active Pending
-
2015
- 2015-02-13 IN IN1185DEN2015 patent/IN2015DN01185A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2881852A1 (en) | 2014-04-03 |
| US20150246871A1 (en) | 2015-09-03 |
| MX2015003912A (es) | 2015-08-05 |
| IN2015DN01185A (enExample) | 2015-06-26 |
| JP6431842B2 (ja) | 2018-11-28 |
| BR112015004591A2 (pt) | 2017-07-04 |
| AU2013323981B2 (en) | 2017-09-14 |
| WO2014052091A1 (en) | 2014-04-03 |
| AU2013323981A1 (en) | 2015-03-05 |
| US9884808B2 (en) | 2018-02-06 |
| CN104661996A (zh) | 2015-05-27 |
| JP2015532280A (ja) | 2015-11-09 |
| KR20150061635A (ko) | 2015-06-04 |
| RU2015107016A (ru) | 2016-11-20 |
| CN110003038A (zh) | 2019-07-12 |
| RU2654461C2 (ru) | 2018-05-18 |
| EP2900632A1 (en) | 2015-08-05 |
| EP2900632B1 (en) | 2019-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |