RU2650778C2 - Композиции и способы применения для определения не4а - Google Patents
Композиции и способы применения для определения не4а Download PDFInfo
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- RU2650778C2 RU2650778C2 RU2013142334A RU2013142334A RU2650778C2 RU 2650778 C2 RU2650778 C2 RU 2650778C2 RU 2013142334 A RU2013142334 A RU 2013142334A RU 2013142334 A RU2013142334 A RU 2013142334A RU 2650778 C2 RU2650778 C2 RU 2650778C2
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- C—CHEMISTRY; METALLURGY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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| PCT/US2011/025321 WO2012112160A1 (en) | 2011-02-17 | 2011-02-17 | Compositions and methods of use for determination of he4a |
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| RU2013142334A RU2013142334A (ru) | 2015-03-27 |
| RU2650778C2 true RU2650778C2 (ru) | 2018-04-17 |
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| US7270960B2 (en) * | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
| CA2827618C (en) * | 2011-02-17 | 2019-08-06 | Fujirebio Diagnostics, Inc. | Compositions and methods of use for the determination of he4a |
| CN106432492A (zh) * | 2015-08-07 | 2017-02-22 | 广州瑞博奥生物技术有限公司 | 针对肿瘤标志物建立的抗体组合及其elisa方法 |
| US11435354B2 (en) * | 2016-02-19 | 2022-09-06 | University Of Miyazaki | Adenocarcinoma detection method |
| USD922352S1 (en) * | 2019-01-04 | 2021-06-15 | Dolby Laboratories Licensing Corporation | Speaker |
| WO2020203478A1 (ja) * | 2019-04-02 | 2020-10-08 | コニカミノルタ株式会社 | 病態情報生成方法、病態情報生成システム、ｈｅ４糖鎖分析キット及びｈｅ４ |
| CN111620939B (zh) * | 2019-10-25 | 2021-01-01 | 南京市妇幼保健院 | 一种用于治疗或辅助治疗卵巢癌的多肽zyx36-58 |
| USD940793S1 (en) * | 2019-11-22 | 2022-01-11 | Microsoft Corporation | Electronic device |
| US20230243835A1 (en) * | 2020-06-23 | 2023-08-03 | Mitsui Chemicals, Inc. | Adenocarcinoma detection method, and examination kit |
| WO2023195629A1 (ko) * | 2022-04-08 | 2023-10-12 | 아주대학교산학협력단 | He4 검출용 펩타이드 및 그 용도 |
| CN117487018B (zh) * | 2023-09-27 | 2024-05-17 | 武汉爱博泰克生物科技有限公司 | 抗人附睾分泌蛋白4的兔单克隆抗体及其应用 |
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| JP4744109B2 (ja) | 2004-07-20 | 2011-08-10 | トヨタ自動車株式会社 | 半導体装置とその製造方法 |
| US7553944B2 (en) * | 2004-07-21 | 2009-06-30 | The University Of Hong Kong | Human virus causing respiratory tract infection and uses thereof |
| ATE408828T1 (de) * | 2005-02-16 | 2008-10-15 | Dana Farber Cancer Inst Inc | Verfahren zur erkennung eines ovarialkarzinoms |
| EP2982761B1 (en) | 2006-01-04 | 2017-10-04 | Fujirebio America, Inc. | Use of he4 and other biochemical markers for assessment of endometrial and uterine cancers |
| AU2007211085A1 (en) | 2006-01-27 | 2007-08-09 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| KR20100015438A (ko) * | 2007-03-09 | 2010-02-12 | 트리패스 이미징, 인코포레이티드 | Ｈｅ4 모노클로날 항체 및 이의 사용 방법 |
| EP2126577B1 (en) | 2007-03-29 | 2013-03-13 | Fujirebio Diagnostics, Inc. | Use of he4 for assessment of breast cancers |
| CA2809368C (en) * | 2010-08-26 | 2021-08-24 | University Of Washington Through Its Center For Commercialization | Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells |
| CA2827618C (en) * | 2011-02-17 | 2019-08-06 | Fujirebio Diagnostics, Inc. | Compositions and methods of use for the determination of he4a |
| US9980982B2 (en) * | 2011-06-06 | 2018-05-29 | Women & Infants Hospital Of Rhode Island | HE4 based therapy for malignant disease |
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Patent Citations (1)
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|---|---|---|---|---|
| WO2003021273A2 (en) * | 2001-08-29 | 2003-03-13 | Pacific Northwest Research Institute | Diagnosis of carcinomas |
Non-Patent Citations (3)
| Title |
|---|
| BINGLE L. et al., The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms. Oncogene, 2002, vol.21, pp.2768-2773. * |
| BINGLE L. et al., The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms. Oncogene, 2002, vol.21, pp.2768-2773. HELLSTROM I. et al., The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma, Cancer Res 2003, vol.63, pp.3695-3700. АЛЬТШУЛЕР E.П. и др. Получение рекомбинантных антител и способы увеличения их аффинности. Успехи биологической химии, 2010, т.50, с.203-258. * |
| HELLSTROM I. et al., The HE4 (WFDC2) Protein Is a Biomarker for Ovarian Carcinoma, Cancer Res 2003, vol.63, pp.3695-3700. АЛЬТШУЛЕР E.П. и др. Получение рекомбинантных антител и способы увеличения их аффинности. Успехи биологической химии, 2010, т.50, с.203-258. * |
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| JP5887364B2 (ja) | 2016-03-16 |
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| AU2011359350B2 (en) | 2016-07-14 |
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| AU2011359350A2 (en) | 2014-05-01 |
| EP2675911A1 (en) | 2013-12-25 |
| KR101854110B1 (ko) | 2018-05-04 |
| IL227924B (en) | 2019-01-31 |
| US20150353629A1 (en) | 2015-12-10 |
| RU2013142334A (ru) | 2015-03-27 |
| KR102074141B1 (ko) | 2020-02-07 |
| BR112013021056B1 (pt) | 2022-03-29 |
| CN103492582B (zh) | 2016-06-22 |
| KR20140025348A (ko) | 2014-03-04 |
| US20180057575A1 (en) | 2018-03-01 |
| CN103492582A (zh) | 2014-01-01 |
| BR112013021056A2 (pt) | 2016-08-09 |
| AU2011359350A1 (en) | 2013-09-12 |
| WO2012112160A1 (en) | 2012-08-23 |
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